US4248634A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Preservative solutions containing sodium dehydroacetate with or without sodium borate decahydrate and/or disodium edetate
Assignee: Individual
•
Filing: 1979-05-04
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Granted: 1981-02-03
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Expires: 1999-05-04
Abstract
Abstract Sodium azide is used as a preservative or bacteriostatic agent of various solutions such as hypertonic phosphate solution, cleaning solutions used in electronic counting equipment, Sorensen's phosphate buffers, lytic agents E and F and the like. Unfortunately, sodium azide, when combined with lead or copper in sink plumbing can produce explosive substances and also is capable of generating toxic gases. By using sodium dehydroacetate with or without sodium borate decahydrate and/or disodium edetate, the disadvantages are removed and at the same time the efficiency of the various solutions is not affected adversely.
Inventors
- 👤 John Forester
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:12
CPC Classifications
A; A01; A01N; A01N43/00; A01N43/02; A01N43/04; A01N43/14; A01N43/16; A01N59/00; A01N59/14; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/101666; Y10T436/105831; Y10T436/107497; Y10T436/108331
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
72 words
A multi-purpose hypertonic phosphate solution for use in automated cell counters, as a cleaning solution in hemoglobinometry and cleaning solutions used on all types of automated cell counters with a lytic agent concentrate consisting essentially of: (a) an osmotically balanced solution of sodium chloride, potassium chloride, sodium phosphate dibasic and sodium phosphate monobasic, and: (b) sodium dehydroacetate, said solution being an aqueous electrolyte solution wherein the sodium dehydroacetate is bacteriostatic in nature.
Claim 2
Dependent Claim
72 words
A multi-purpose hypertonic phosphate solution for use in automated cell counters, as a cleaning solution in hemoglobinometry and cleaning solutions used on all types of automated cell counters with a lytic agent concentrate consisting essentially of: (a) an osmotically balanced solution of sodium chloride, potassium chloride, sodium phosphate dibasic and sodium phosphate monobasic, and: (b) sodium dehydroacetate, said solution being an aqueous electrolyte solution wherein the sodium dehydroacetate is bacteriostatic in nature.
Claim 3
Dependent Claim
10 words
The solution according to claim 1 which includes disodium edetate.
Claim 4
Dependent Claim
11 words
The solution according to claim 1 which includes sodium borate decahydrate.
Claim 5
Dependent Claim
11 words
The solution according to claim 2 which includes sodium borate decahydrate.
Claim 6
Dependent Claim
43 words
The solution according to claim 1 in which the approximate proportions by volume comprise sodium chloride 0.8% to 0.83%, sodium phosphate dibasic 0.170% to 0.175%, sodium phosphate monobasic 0.029% to 0.035%, potassium chloride 0.038% to 0.040%, and the sodium dehydroacetate 0.45% to 0.50%.
Claim 7
Dependent Claim
18 words
The solution according to claim 5 which includes disodium edetate in the proportion of approximately 0.1% by volume.
Claim 8
Dependent Claim
18 words
The solution according to claim 5 which includes sodium borate decahydrate in the proporation of 0.06% to 0.10%.
Claim 9
Dependent Claim
18 words
The solution according to claim 6 which includes sodium borate decahydrate in the proportion of 0.06% to 0.10%.
Claim 10
Dependent Claim
49 words
The solution according to claims 1, 2 or 3 together with a lytic agent concentrate, said lytic agent concentrate comprising approximately 3.2 grams of potassium cyanide, 78.0 grams of cetyl trimethyl ammonium bromide, approximately 110.0 ml of glycerol USP, with said solution making up the amount of one liter.
Claim 11
Dependent Claim
54 words
The solution according to claims 1, 2 or 3 together with a lytic agent concentrate, said lytic agent concentrate comprising approximately 0.25 grams of potassium cyanide, 20.0 grams of cetyl trimethyl ammonium bromide, with said solution making up a volume of one liter, the pH being adjusted to approximately 7.4 with concentrated phosphoric acid.
Claim 12
Dependent Claim
37 words
The solution according to claims 1, 2 or 3 together with a non-ionic surfactant selected from the group comprising Triton X-100, Brij 35 and Triton CF-54, said non-ionic surfactant comprising approximately 0.1% by volume of the total.
References Cited (Backward Citations)
US3962125A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-03 | 1984-08-04 | 1985-02-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-03 | 1988-08-04 | 1989-02-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-03 | 1992-08-04 | 1993-02-03 | $7700.00 | Window Closed / Lapsed |