Dental cement containing poly(carboxylic acid), chelating agent and glass cement powder

Claim 2

A process for the production of a poly(carboxylate) cement which comprises mixing a water soluble poly(carboxylic acid) having a relative viscosity of from 1.05 to 2.00 measured with a capillary viscometer of a 1% by weight to volume solution of the poly(carboxylic acid) in twice molar sodium hydroxide solution at 25° C. relative to the viscosity of the twice molar sodium hydroxide solution with an ion leachable glass cement powder in the presence of a water soluble chelating agent selected from the group consisting of compounds containing both chelating hydroxyl and carboxyl groups and metal chelates, and water to give a plastic mass which rapidly hardens to form a poly(carboxylate) cement, the amount of the chelating agent being at least 0.01% by weight based on the weight of the poly(carboxylic acid) and sufficient to improve the rate of hardening of the cement, as compared to the rate of hardening of the cement in the absence of said compound.

Claim 3

A process according to claim 1, in which the poly(carboxylic acid) is in the form of an aqueous solution containing from 20 to 65% by weight of the poly(carboxylic acid).

Claim 4

A process according to claim 2 in which the powder/liquid ratio is in the range of 0.5:1 to 5:1.

Claim 5

A process according to claim 1 in which the chelating agent is tartaric acid or citric acid.

Claim 6

A process according to claim 2 in which the chelating agent is a di- or tri-valent metal chelate.

Claim 7

A process according to claim 1, in which the poly(carboxylic acid) is a homopolymer of acrylic acid or a copolymer of acrylic acid and at least one comonomer selected from the group consisting of 2-chloroacrylic acid, 3-chloroacrylic acid, 2-bromoacrylic acid, 3-bromoacrylic acid, methacrylic acid, itaconic acid, maleic aid, glutaconic acid, aconitic acid, citraconic acid, mesaconic acid, fumaric acid, tiglicinic acid, acrylamide, acrylonitrile, vinyl chloride, allyl chloride, vinyl acetate and 2-hydroxymethyl methacrylate.

Claim 8

A process according to claim 1 in which the cement powder is selected from the group consisting of aluminosilicate glass powders and fluoroaluminosilicate glass powders.

Claim 9

A cement composition consisting essentially of an intimately blended mixture of an ion-leachable surgically acceptable glass cement powder, a water soluble poly(carboxylic acid) having a relative viscosity of from 1.05 to 2.00 measured with a capillary viscometer of a 1% by weight to volume solution of the poly(carboxylic acid) in twice molar sodium hydroxide solution at 25° C. relative to the viscosity of the twice molar sodium hydroxide solution and a water-soluble chelating agent selected from the group consisting of compounds containing both chelating hydroxyl and carboxyl groups and metal chelates, the ratio of cement powder to poly(carboxylic acid) being from 1:1 to 10:1, and said chelating agent being present in an amount of at least 0.01% by weight based on the weight of the poly(carboxylic acid) and sufficient to increase the rate of hardening of the cement as compared to the rate of hardening of the cement in the absence of said chelating agent, said cement composition being characterized by forming a poly(carboxylate) cement upon the addition of water thereto.

Claim 10

A cement composition consisting essentially of an intimately blended mixture of an ion-leachable surgically acceptable glass cement powder, a water soluble poly(carboxylic acid) having a relative viscosity of from 1.05 to 2.00 measured with a capillary viscometer of a 1% by weight to volume solution of the poly(carboxylic acid) in twice molar sodium hydroxide solution at 25° C. relative to the viscosity of the twice molar sodium hydroxide solution and a water-soluble chelating agent selected from the group consisting of compounds containing both chelating hydroxyl and carboxyl groups and metal chelates, the ratio of cement powder to poly(carboxylic acid) being from 1:1 to 10:1, and said chelating agent being present in an amount of at least 0.01% by weight based on the weight of the poly(carboxylic acid) and sufficient to increase the rate of hardening of the cement as compared to the rate of hardening of the cement in the absence of said chelating agent, said cement composition being characterized by forming a poly(carboxylate) cement upon the addition of water thereto.

Claim 11

The cement composition according to claim 8, in which the chelating agent is tartaric acid or citric acid.

Claim 12

The cement composition according to claim 8, in which the chelating agent is a di- or tri-valent metal chelate.

Claim 13

The cement composition according to claim 8, in which the poly(carboxylic acid) is a homopolymer of acrylic acid or copolymer of acrylic acid and at least one comonomer selected from the group consisting of 2-chloroacrylic acid, 3-chloroacrylic acid, 2-bromoacrylic acid, 3-bromoacrylic acid, methacrylic acid, itaconic acid, maleic acid, glutaconic acid, aconitic acid, citraconic acid, mesaconic acid, fumaric acid, tiglicinic acid, acrylamide, acrylonitrile, vinyl chloride, allyl chloride, vinyl acetate and 2-hydroxyethyl methacrylate.

Claim 14

The cement composition according to claim 8, in which the cement powder is selected from the group consisting of aluminosilicate glass powders and fluoroaluminosilicate glass powders.

Claim 15

The cement composition according to claim 8, wherein said chelating agent is tartaric acid.

Claim 16

The cement composition according to claim 8, wherein said chelating agent is selected from the group consisting of salicylic acid, citric acid, 2,4- and 2,6-dihydroxybenzoic acids, dihydroxy tartaric acid, tartaric acid, and complexes of β-diketones with aluminum and chromium.

Claim 17

The cement composition according to claim 8, wherein said glass powder is an aluminosilicate glass powder.

Claim 18

The cement composition according to claim 13, wherein said glass powder is a fluoroaluminosilicate glass powder.

Claim 19

A hardened poly(carboxylate) cement, particularly for dental purposes, which has been prepared by the process consisting essentially of mixing a water soluble poly(carboxylic acid) having a relative viscosity of from 1.05 to 2.00 measured with a capillary viscometer of a 1% by weight to volume solution of the poly(carboxylic acid) in twice molar sodium hydroxide solution at 25° C. relative to the viscosity of the twice molar sodium hydroxide solution with an ion-leachable surgically acceptable glass cement powder in the presence of water and in the presence of a water soluble chelating agent selected from the group consisting of compounds containing both chelating hydroxyl and carboxyl groups and metal chelates, the chelating agent being present in an amount of at least 0.01% by weight based on the weight of the poly(carboxylic acid) and sufficient to improve the rate of hardening of the cement as compared to the rate of hardening of the cement in the absence of said chelating agent.

Claim 20

A hardened poly(carboxylate) cement, particularly for dental purposes, which has been prepared by the process consisting essentially of mixing a water soluble poly(carboxylic acid) having a relative viscosity of from 1.05 to 2.00 measured with a capillary viscometer of a 1% by weight to volume solution of the poly(carboxylic acid) in twice molar sodium hydroxide solution at 25° C. relative to the viscosity of the twice molar sodium hydroxide solution with an ion-leachable surgically acceptable glass cement powder in the presence of water and in the presence of a water soluble chelating agent selected from the group consisting of compounds containing both chelating hydroxyl and carboxyl groups and metal chelates, the chelating agent being present in an amount of at least 0.01% by weight based on the weight of the poly(carboxylic acid) and sufficient to improve the rate of hardening of the cement as compared to the rate of hardening of the cement in the absence of said chelating agent.

Claim 21

The cement according to claim 17, wherein the reaction mixture consists essentially of from 15 to 85% by weight of the cement powder, from 3 to 50% by weight of the poly(carboxylic acid) and from 5 to 70% by weight of water, based on the total weight of the composition, and from at least 0.01% by weight, based on the poly(carboxylic acid), of said chelating agent.

Claim 22

The cement according to claim 17, in which the chelating agent is tartaric acid or citric acid.

Claim 23

The cement according to claim 17, in which the chelating agent is a di- or tri-valent metal chelate.

Claim 24

The cement according to claim 17, in which the poly(carboxylic acid) is a homopolymer of acrylic acid or a copolymer of acrylic acid and at least one comonomer selected from the group consisting of 2-chloroacrylic acid, 3-chloroacrylic acid, 2-bromoacrylic acid, 3-bromoacrylic acid, methacrylic acid, itaconic acid, maleic acid, glutaconic acid, aconitic acid, citraconic acid, mesaconic acid, fumaric acid, tiglicinic acid, acrylamide, acrylonitrile, vinyl chloride, allyl chloride, vinyl acetate and 2-hydroxyethyl methacrylate.

Claim 25

The cement according to claim 17, in which the cement powder is selected from the group consisting of aluminosilicate glass powders and fluoroaluminosilicate glass powders.