US4165632A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of measuring the fluidity of liquids for medical and pharmaceutical purposes, and apparatus for performing the method
Assignee: Individual
•
Filing: 1977-03-25
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Granted: 1979-08-28
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Expires: 1997-03-25
Abstract
Abstract A method and apparatus for determining the fluidity of a liquid such as blood or serum having the steps of drawing the liquid from the source through a capillary tube measuring cell into a reservoir unit and returning the liquid back through the tube at a constant flow velocity while measurements are made. The pressure difference between the ends of the capillary tube are directly related to the viscosity of the liquid.
Inventors
- 👤 Gerhard Weber
- 👤 Siegfried Peters
- 👤 Jurgen Kunzel
- 👤 Torsten Kreisel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 07:55
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6866; A61B5/02; A61B5/02028; A61B5/02035; A61B5/026; A61B5/0275; G; G01; G01N; G01N11/00; G01N11/02; G01N11/04; G01N11/08; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49
Claims Analysis
Total Claims: 30
Claim 1
Independent Claim
101 words
A method of determining the fluidity of a liquid, such as of blood or serum, in a capillary, for medical and pharmaceutical purposes, comprising the steps of drawing the liquid from a vessel, through a measuring cell containing a capillary tube into a reservoir unit and thereafter returning the liquid to its original vessel through the measuring cell while performing viscosity measurements at a velocity of flow that remains constant for a given period of time, said measured liquid being drawn into and expelled from the measuring cell by pump means through an interposed buffer liquid, such as an infusion solution.
Claim 2
Independent Claim
101 words
A method of determining the fluidity of a liquid, such as of blood or serum, in a capillary, for medical and pharmaceutical purposes, comprising the steps of drawing the liquid from a vessel, through a measuring cell containing a capillary tube into a reservoir unit and thereafter returning the liquid to its original vessel through the measuring cell while performing viscosity measurements at a velocity of flow that remains constant for a given period of time, said measured liquid being drawn into and expelled from the measuring cell by pump means through an interposed buffer liquid, such as an infusion solution.
Claim 3
Dependent Claim
54 words
The method according to claim 1, in which the liquid to be measured is drawn no further than will ensure that the pump means are wetted only by the buffer liquid and in which the entire volume of the apparatus not filled with the liquid to be measured is filled with the buffer liquid.
Claim 4
Dependent Claim
41 words
The method according to claim 2, in which at the end of a measurement fresh buffer liquid is drawn in through a branch supply pipe and that the measuring cell and the reservoir unit are flushed out with this buffer liquid.
Claim 5
Dependent Claim
32 words
The method according to claim 1, in which the pressure difference between the two ends of the measuring capillary tube is determined during the return of the liquid to its original vessel.
Claim 6
Dependent Claim
28 words
The method according to claim 4, in which the result of the measurement of the pressure difference is converted into electrical signals which are fed to a computer.
Claim 7
Dependent Claim
30 words
The method according to claim 5, in which a programmed control is provided to time the operation of the means for drawing in and returning the liquid to be measured.
Claim 8
Dependent Claim
21 words
The method according to claim 1, in which the measuring cell and the reservoir unit are maintained at a constant temperature.
Claim 9
Independent Claim
149 words
An apparatus for determining the fluidity of a liquid, such as blood or serum, in a capillary, for medical and pharmaceutical purposes comprising: a measuring capillary tube having two ends, a diameter, a length and a cross sectional area; a source of the liquid; first connecting means for interconnecting said source to one end of said capillary tube; a reservoir unit having two ends; second connecting means connecting one end of said reservoir unit to the other end of said capillary tube; means for drawing in and returning said liquid through said capillary tube operatively associated with the other end of said reservoir unit; third connecting means connecting said means for drawing and returning liquid to the other end of said reservoir unit; and measuring means for measuring the fluidity of the liquid being passed through said capillary tube, said measuring means being operatively connected to said capillary tube.
Claim 10
Independent Claim
149 words
An apparatus for determining the fluidity of a liquid, such as blood or serum, in a capillary, for medical and pharmaceutical purposes comprising: a measuring capillary tube having two ends, a diameter, a length and a cross sectional area; a source of the liquid; first connecting means for interconnecting said source to one end of said capillary tube; a reservoir unit having two ends; second connecting means connecting one end of said reservoir unit to the other end of said capillary tube; means for drawing in and returning said liquid through said capillary tube operatively associated with the other end of said reservoir unit; third connecting means connecting said means for drawing and returning liquid to the other end of said reservoir unit; and measuring means for measuring the fluidity of the liquid being passed through said capillary tube, said measuring means being operatively connected to said capillary tube.
Claim 11
Dependent Claim
71 words
The apparatus according to claim 8, wherein said reservoir comprises a tube having a diameter and a length, said diameter of said reservoir tube being of the same order of magnitude as the diameter of the capillary tube, both of said diameters being greater than the largest diameter of any object suspended in the liquid, and said length of said reservoir tube being longer than said length of said capillary tube.
Claim 12
Dependent Claim
31 words
The apparatus according to claim 9, wherein said first, second, and third connecting means are made from a material selected from the group consisting of polyamide plastic, platinum, and stainless steel.
Claim 13
Dependent Claim
44 words
The apparatus according to claim 10, wherein said first, second, and third connecting means are flexible tubing made of polyamide plastic and said capillary tube and said reservoir tube are made of a material selected from the group consisting of platinum and stainless steel.
Claim 14
Dependent Claim
37 words
The apparatus according to claim 8, further comprising a first thermostatically controlled jacket surrounding in a temperature controlling relationship said capillary tube and a second thermostatically controlled jacket surrounding in a temperature controlling relationship said reservoir unit.
Claim 15
Dependent Claim
36 words
The apparatus according to claim 8, wherein said measuring means comprises two precision pressure measuring devices, each connected to one end of said capillary tube and means for determining the difference in measurement of the devices.
Claim 16
Dependent Claim
35 words
The apparatus according to claim 13, wherein said measuring means further comprises means for converting the measurements of each of the devices to electrical signals and said means for determining the difference comprises a computer.
Claim 17
Dependent Claim
38 words
The apparatus according to claim 13, further comprising a first pipe union joining said first connecting means and one end of said capillary tube having a cross-sectional area, said pressure measuring device being fitted to said pipe union.
Claim 18
Dependent Claim
24 words
The apparatus according to claim 15, wherein said cross-sectional area of said pipe union is greater than said cross-sectional area of said capillary tube.
Claim 19
Dependent Claim
29 words
The apparatus according to claim 15, wherein said pressure measuring devices each comprise a diaphragm mounted in said pipe union and a strain gauge operatively connected to said diaphragm.
Claim 20
Dependent Claim
40 words
The apparatus according to claim 8, further comprising additional fluid means for adding a buffer liquid connected to said third connecting means between said reservoir unit and said means for drawing in and returning said liquid through said capillary tube.
Claim 21
Dependent Claim
36 words
The apparatus according to claim 18, wherein said additional fluid means includes a first valve and said third connecting means includes a second valve between where said additional fluid means is connected and said reservoir unit.
Claim 22
Dependent Claim
35 words
The apparatus according to claim 8, wherein said measuring means are located at the edge of the flow cross-section of the ends of said capillary tube and are stressed by the pressure of the liquid.
Claim 23
Dependent Claim
82 words
The apparatus according to claim 20, said measuring means comprises two measuring channels, one being at each end of said capillary tube, and two measuring tubes, one at each end of said capillary tube mounted into the capillary tube and corresponding in size with the flow-cross-section of the liquid, said tubes being located within the measuring channels, the tubes and the measuring channels each consisting of an elastic, liquid-pressure-transmitting material, and a pressure-measuring device abutting the outer wall of the measuring channel.
Claim 24
Dependent Claim
25 words
The apparatus according to claim 21, wherein the outer diameter of each measuring tube is larger than the inner diameter of the respective measuring channel.
Claim 25
Dependent Claim
47 words
The apparatus according to claim 21, wherein the measuring channel comprises a piece of a tube which penetrates a borehole of a casing and is fastened therein, whereby the casing is provided with a cavity running vertical to the borehole, in which the pressure-measuring device is fastened.
Claim 26
Dependent Claim
25 words
The apparatus according to claim 21, wherein said pressure-measuring device comprises stretch-measuring tapes which are fastened immediately to the outside wall of the measuring channel.
Claim 27
Dependent Claim
38 words
The apparatus according to claim 21, wherein the tubes, at least in the area in which they affect the pressure-measuring device, within the measuring channel, are more elastic, being of a thinner wall, than in their remaining area.
Claim 28
Dependent Claim
30 words
The apparatus according to claim 21, wherein the tubes are arranged to be replaceable by being guidable through the measuring channels and insertable onto the ends of the capillary tube.
Claim 29
Independent Claim
159 words
A method of determining the fluidity of a liquid, such as a blood or serum, in a capillary, for medical and pharmaceutical purposes, comprising the steps of drawing the liquid from a vessel, through a measuring cell containing a capillary tube onto a reservoir unit and thereafter returning the liquid to its original vessel through the meauring cell while performing viscosity measurements by determining the pressure difference between the two ends of the measuring capillary tube and converting the result of the measurement into electrical signals which are fed to a computer, said measurements being taken at a velocity of flow that remains constant for a given period of time, the liquid to be measured being forced through the measuring capillary tube at consecutively different velocities which are each kept constant for predetermined periods of time by a means for drawing in and returning the liquid, said means having a programmed control for timing the operation of the same.
Claim 30
Independent Claim
159 words
A method of determining the fluidity of a liquid, such as a blood or serum, in a capillary, for medical and pharmaceutical purposes, comprising the steps of drawing the liquid from a vessel, through a measuring cell containing a capillary tube onto a reservoir unit and thereafter returning the liquid to its original vessel through the meauring cell while performing viscosity measurements by determining the pressure difference between the two ends of the measuring capillary tube and converting the result of the measurement into electrical signals which are fed to a computer, said measurements being taken at a velocity of flow that remains constant for a given period of time, the liquid to be measured being forced through the measuring capillary tube at consecutively different velocities which are each kept constant for predetermined periods of time by a means for drawing in and returning the liquid, said means having a programmed control for timing the operation of the same.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-08-27 | 1983-02-26 | 1983-08-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-08-27 | 1987-02-26 | 1987-08-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-08-27 | 1991-02-26 | 1991-08-28 | $7700.00 | Window Closed / Lapsed |