US4154936A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted acyl derivatives of amino acids
Assignee: ER Squibb and Sons LLC
•
Filing: 1978-03-24
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Granted: 1979-05-15
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Expires: 1998-03-24
Abstract
Abstract New substituted acyl derivatives of amino acids which have the general formula <IMAGE> are useful as angiotensin converting enzyme inhibitors.
Inventors
- 👤 Miguel A. Ondetti
- 👤 Frank L. Weisenborn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:40
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/60; A; A61; A61P; A61P9/00; A61P9/12; C07C; C07C323/00; C07C327/00; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/18; C07D209/20
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
59 words
A compound of the formula ##STR19## wherein R 1 is hydroxy or lower alkoxy; A and B together form a (CH 2 ) p bridge which completes an unsubstituted ring of 5 or 6 atoms with the nitrogen and carbon to which they are joined or said ring substituted with a hydroxy group; and p is 3 or 4.
Claim 2
Dependent Claim
59 words
A compound of the formula ##STR19## wherein R 1 is hydroxy or lower alkoxy; A and B together form a (CH 2 ) p bridge which completes an unsubstituted ring of 5 or 6 atoms with the nitrogen and carbon to which they are joined or said ring substituted with a hydroxy group; and p is 3 or 4.
Claim 3
Dependent Claim
20 words
A compound as in claim 1 wherein A and B together are (CH 2 ) 4 --completing a six-membered ring.
Claim 4
Dependent Claim
20 words
A compound as in claim 1 wherein A and B together are (CH 2 ) 3 --completing a five-membered ring.
References Cited (Backward Citations)
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US3510504A
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US3624143A
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US3835149A
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US4046889A
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US4116962A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-14 | 1982-11-13 | 1983-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-14 | 1986-11-13 | 1987-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-14 | 1990-11-13 | 1991-05-15 | $7700.00 | Window Closed / Lapsed |