US4153686A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the preparation of glucoproteins as well as the use thereof
Assignee: Individual
•
Filing: 1977-01-18
•
Granted: 1979-05-08
•
Expires: 1997-01-18
Abstract
Abstract The use of a stabilized glucoprotein for the preparation of medicaments with a potentiating action of active substances is described wherein the separate glucoprotein is stabilized with an inorganic electrolyte and/or a saccharide and albumin mixture combinations with antibiotics, ampicillin, etc., are described.
Inventors
- 👤 Hans-Hugo Nagel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 07:44
CPC Classifications
C; C12; C12P; C12P21/00; C12P21/005; A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/78
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
87 words
Use of stabilised glucoprotein for the preparation of medicaments with a potentiating action on the active substances, whereby 10 2 to 10 6 parts by weight of the active medicament substance is used per 1 part by weight of glucoprotein, wherein said stabilized glucoprotein is prepared by reacting an aqueous suspension of yeast with monosaccharides and native albumin as starting substance, and separating the glucoprotein from the resulting reaction medium, and thereafter adding an inorganic electrolyte and/or a saccharide and albumin mixture thereto to stabilize the same.
Claim 2
Dependent Claim
87 words
Use of stabilised glucoprotein for the preparation of medicaments with a potentiating action on the active substances, whereby 10 2 to 10 6 parts by weight of the active medicament substance is used per 1 part by weight of glucoprotein, wherein said stabilized glucoprotein is prepared by reacting an aqueous suspension of yeast with monosaccharides and native albumin as starting substance, and separating the glucoprotein from the resulting reaction medium, and thereafter adding an inorganic electrolyte and/or a saccharide and albumin mixture thereto to stabilize the same.
Claim 3
Dependent Claim
19 words
Use according to claim 1, characterised in that the glucoprotein has an average molecular weight of 55,000 to 65,000.
Claim 4
Dependent Claim
14 words
Use according to claim 1, wherein lactose or glucose is used as the monosaccharide.
Claim 5
Dependent Claim
14 words
Use according to claim 1, wherein lactalbumin or gelatin is used as the albumin.
Claim 6
Dependent Claim
13 words
Use according to claim 1, wherein said reacting is performed at ambient temperature.
Claim 7
Dependent Claim
18 words
Use according to claim 1, wherein said reacting is performed at pH values of approximately 6 to 7.5.
Claim 8
Dependent Claim
14 words
Use according to claim 1, wherein said glucoprotein is separated by dialysis and dried.
References Cited (Backward Citations)
US3637640A
Cited
US3847890A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-07 | 1982-11-06 | 1983-05-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-07 | 1986-11-06 | 1987-05-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-07 | 1990-11-06 | 1991-05-08 | $7700.00 | Window Closed / Lapsed |