US4151349A
Expired / Lapsed
US
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Crystalline potassium salt of β-nicotinamide adenine dinucleotide phosphoric acid and method for its preparation
Assignee: Roche Diagnostics GmbH
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Filing: 1977-09-23
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Granted: 1979-04-24
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Expires: 1997-09-23
Abstract
Abstract The invention provides a novel crystalline potassium salt of β-nicotinamide adenine dinucleotide phosphoric acid (β-NADP-K), having a primitively orthorhombic crystal system, which salt is more pure and more stable than the conventional amorphous form, and is advantageously not hygroscopic. The novel salt is produced by treating a dilute aqueous solution of the potassium salt of β-nicotinamide adenine dinucleotide phosphoric acid with a hydrophilic water soluble organic solvent at a pH value of 2 to 5 until turbidity sets in, permitting crystallization and then separating the crystals.
Inventors
- 👤 Heinrich Traeger
- 👤 Herbert Brustmann
- 👤 Erich Haid
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:09
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; C07H19/20; C07H19/207
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
41 words
Crystalline potassium salt of β-nicotinamide adenine dinucleotide phosphoric acid in a primitively orthorhombic crystal system, with the space group P2 1 2 1 2 1 or P2 1 2 1 2, and the cell dimensions a=52.23 A±0.03, b=16.89 A±0.03, c=8.45 A±0.03.
Claim 2
Dependent Claim
41 words
Crystalline potassium salt of β-nicotinamide adenine dinucleotide phosphoric acid in a primitively orthorhombic crystal system, with the space group P2 1 2 1 2 1 or P2 1 2 1 2, and the cell dimensions a=52.23 A±0.03, b=16.89 A±0.03, c=8.45 A±0.03.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-23 | 1982-10-23 | 1983-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-23 | 1986-10-23 | 1987-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-23 | 1990-10-23 | 1991-04-24 | $7700.00 | Window Closed / Lapsed |