US4148606A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sterilization of dialyzer
Assignee: Toray Industries Inc
•
Filing: 1977-09-22
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Granted: 1979-04-10
•
Expires: 1997-09-22
Abstract
Abstract Sterilization of a dialyzer, using a saturated and wet semipermeable membrane and irradiating said dialyzer in the presence of an antibacterial agent. The method is especially effective and safe, affords elimination of labor for preparation for dialysis, and has special utility when the dialyzer is an artificial kidney containing a multiplicity of hollow filament semipermeable membranes.
Inventors
- 👤 Minoru Morita
- 👤 Yoshishige Fujii
- 👤 Yasuo Taniguchi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:46
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/16; A61L2/18; A61L2/186; B; B01; B01D; B01D65/00; B01D65/02; B01D65/022; B01D2321/00; B01D2321/16; B01D2321/34; B01D2321/346
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
61 words
A wet state sterilization method for a semipermeable membrane of a dialyzer the steps which comprise: a. saturating a semipermeable membrane of a dialyzer with an antibacterial agent suspended in a liquid; and b. irradiating said saturated membrane with microbiocidal radiation rays in the presence of said agent, said rays being applied in an amount to kill substantially all remaining microorganisms.
Claim 2
Dependent Claim
61 words
A wet state sterilization method for a semipermeable membrane of a dialyzer the steps which comprise: a. saturating a semipermeable membrane of a dialyzer with an antibacterial agent suspended in a liquid; and b. irradiating said saturated membrane with microbiocidal radiation rays in the presence of said agent, said rays being applied in an amount to kill substantially all remaining microorganisms.
Claim 3
Dependent Claim
13 words
A method according to claim 1, wherein said dialyzer is an artificial kidney.
Claim 4
Dependent Claim
14 words
A method according to claim 1, wherein said semipermeable membrane is a hollow filament.
Claim 5
Dependent Claim
18 words
A method according to claim 1, wherein said liquid is water and said antibacterial agent is hydrogen peroxide.
Claim 6
Dependent Claim
13 words
A method according to claim 1, wherein said semipermeable membrane comprises polymethyl methacrylate.
Claim 7
Dependent Claim
12 words
A method according to claim 1, wherein said semipermeable membrane comprises cellulose.
Claim 8
Dependent Claim
12 words
A method according to claim 1, wherein said semipermeable membrane comprises polyacrylonitrile.
Claim 9
Dependent Claim
12 words
A method according to claim 1, wherein said semipermeable membrane comprises polycarbonate.
Claim 10
Dependent Claim
18 words
A method according to claim 1, wherein the amount of irradiated radiation rays is at least 2 Mrad.
Claim 11
Dependent Claim
12 words
A method according to claim 1, wherein said radiation rays are gamma-rays.
Claim 12
Dependent Claim
21 words
A method according to claim 1, wherein the amount of antibacterial agent in said aqueous solution is at least 4 ppm.
Claim 13
Dependent Claim
13 words
A method according to claim 1, wherein said radiation rays are electron rays.
Claim 14
Dependent Claim
52 words
A wet state sterilization method for a hollow filament semipermeable membrane, of an artificial kidney comprising: a. saturating a hollow filament semipermeable membrane of an artificial kidney in an aqueous solution containing hydrogen peroxide; and b. subjecting said saturated semipermeable membrane to irradiation with gamma-rays in the presence of said hydrogen peroxide.
Claim 15
Dependent Claim
52 words
A wet state sterilization method for a hollow filament semipermeable membrane, of an artificial kidney comprising: a. saturating a hollow filament semipermeable membrane of an artificial kidney in an aqueous solution containing hydrogen peroxide; and b. subjecting said saturated semipermeable membrane to irradiation with gamma-rays in the presence of said hydrogen peroxide.
Claim 16
Dependent Claim
21 words
A method according to claim 13, wherein the amount of hydrogen peroxide in said aqueous solution is at least 4 ppm.
Claim 17
Dependent Claim
13 words
A method according to claim 13, wherein said semipermeable membrane comprises polymethyl methacrylate.
Claim 18
Dependent Claim
12 words
A method according to claim 13, wherein said semipermeable membrane comprises cellulose.
Claim 19
Dependent Claim
12 words
A method according to claim 13, wherein said semipermeable membrane comprises polyacrylonitrile.
Claim 20
Dependent Claim
12 words
A method according to claim 13, wherein said semipermeable membrane comprises polycarbonate.
Claim 21
Dependent Claim
17 words
A method according to claim 13, wherein the amount of irradiated gamma-rays is at least 2 Mrad.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-09 | 1982-10-09 | 1983-04-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-09 | 1986-10-09 | 1987-04-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-09 | 1990-10-09 | 1991-04-10 | $7700.00 | Window Closed / Lapsed |