US4131597A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bioactive composite material process of producing and method of using same
Assignee: Ernst Leitz Wetzlar GmbH
•
Filing: 1976-01-12
•
Granted: 1978-12-26
•
Expires: 1996-01-12
Abstract
Abstract The composite material for prosthetic purposes of the present invention is essentially composed of a plastic matrix, preferably of a methacrylate plastic, and at least one bioactive filler material, preferably a glass ceramic material of apatite crystal structure. The finely comminuted bioactive material may be homogeneously or nonhomogeneously incorporated in the plastic matrix. Reinforcing additives such as glass fibers and the like may also be incorporated into the mixture of plastic matrix and bioactive material in order to improve the mechanical strength properties. The bioactive material may be admixed to a mixture of methacrylate monomer and curing agent or to a prepolymer obtained therefrom. The composite material is useful as bone cement bone or tooth replacement material, and in general for prosthetic purposes in surgery and orthopedics.
Inventors
- 👤 Waldemar Bluethgen
- 👤 Heinz Broemer
- 👤 Klaus K. Deutscher
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 21:01
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/56; A61B17/58; A61B17/88; A61B17/8802; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/30; A61F2/3094; A61F2/30965; A61L; A61L27/00; A61L27/40; A61L27/44; A61L27/46; C; C03; C03C; C03C10/00; C03C10/0009; C08; C08K; C08K3/00; C08K3/18; C08K3/20; C08K3/22; C08K3/34; A61F2/46; A61F2002/4631; Y; Y10; Y10S; Y10S623/00; Y10S623/924
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
29 words
A composite material for prosthetic purposes, said material consisting of a polymerizable plastic matrix and between about 10 and about 70% by volume of inorganic bioactive and biocompatible material.
Claim 2
Dependent Claim
29 words
A composite material for prosthetic purposes, said material consisting of a polymerizable plastic matrix and between about 10 and about 70% by volume of inorganic bioactive and biocompatible material.
Claim 3
Dependent Claim
102 words
The composite material of claim 1, in which the bioactive material is a bioactive glass ceramic material having an apatite crystal phase and being of the following composition, in weight percent: between about 20.0% and about 60.0% of silicon dioxide SiO 2 , between about 5.0% and about 40.0% of phosphorus pentoxide P 2 O 5 , between about 2.7% and about 20.0% of sodium oxide Na 2 O, between about 0.4% and about 20.0% of potassium oxide K 2 O, between about 2.0% and about 30.0% of magnesium oxide MgO, and between about 5.0% and about 40.0% of calcium oxide CaO.
Claim 4
Dependent Claim
19 words
The composite material of claim 2, additionally containing between about 0.005% and about 3.0% of fluroine F 2 .
Claim 5
Dependent Claim
29 words
The composite material of claim 1, in which the bioactive material is incorporated homogeneously in the plastic matrix so as to achieve isotropic particle distribution in said plastic matrix.
Claim 6
Dependent Claim
24 words
The composite material of claim 1, in which the bioactive material is of a particle size between about 90 μ m. and 250 μm.
Claim 7
Dependent Claim
25 words
The composite material of claim 2, in which the bioactive material is of a particle size between about 90 μ m. and about 250 μm.
Claim 8
Dependent Claim
25 words
The composite material of claim 3, in which the bioactive material is of a particle size between about 90 μ m. and about 250 μm.
Claim 9
Dependent Claim
29 words
The composite material of claim 1, in which the bioactive material is incorporated non-homogeneously in the plastic matrix so as to achieve anistropic particle distribution in said plastic matrix.
Claim 10
Dependent Claim
30 words
The composite material of claim 1, said composite material having admixed thereto at least one reinforcing component consisting of a fiber material so as to improve its mechanical strength properties.
Claim 11
Dependent Claim
15 words
The composite material of claim 9, in which the reinforcing component consists of glass fibers.
Claim 12
Dependent Claim
16 words
The composite material of claim 1, in which the polymerizable plastic matrix is a methacrylate matrix.
Claim 13
Dependent Claim
36 words
In a process of producing the composite material of claim 1, the steps comprising a) adding a hardening agent to a fluid monomeric plastic material, and b) mixing thereto the finely comminuted bioactive glass ceramic material.
Claim 14
Dependent Claim
112 words
The process of claim 12, in which the fluid monomeric plastic material is a methacrylate plastic and the bioactive glass ceramic material is the glass ceramic material having an apatite crystal phase and being of the following composition, in weight percent: between about 20.0% and about 60.0% of silicon dioxide SiO 2 , between about 5.0% and about 40.0% of phosphorus pentoxide P 2 O 5 , between about 2.7% and about 20.0% of sodium oxide Na 2 O, between about 0.4% and about 20.0% of potassium oxide K 2 0, between about 2.0% and about 30.0% of magnesium oxide MgO, and between about 5.0% and about 40.0% of calcium oxide CaO.
Claim 15
Dependent Claim
58 words
The process of claim 12, in which in steps (b) the finely comminuted glass ceramic material is added to a mixture of methyl methacrylate and hardening agent after prepolymerization of said mixture to a predetermined viscosity so as to achieve predetermined fractional segregation and anistropic distribution of the particles of bioactive glass ceramic material within the composite material.
Claim 16
Dependent Claim
23 words
The process of claim 12, in which a catalyst is added as additional component to the mixture of components of the composite material.
Claim 17
Dependent Claim
22 words
The process of claim 12, in which the resulting mixture is caused to polymerize completely so as to produce a prosthetic material.
Claim 18
Dependent Claim
33 words
The process of claim 12, in which the resulting mixture is applied to the bone and implant and is caused to polymerize completely "in vivo" to firmly attach the implant to the bone.
Claim 19
Dependent Claim
23 words
The process of claim 16, in which the mixture of components of the composite material is cooled during polymerization of the plastic material.
Claim 20
Dependent Claim
23 words
The process of claim 17, in which the mixture of components of the composite material is cooled during polymerization of the plastic material.
Claim 21
Dependent Claim
39 words
In a method of applying a bone cement to implants so as to firmly attach the implants to the respective skeleton parts of the body, the improvement comprising applying the bioactive composite material of claim 1 to said implants.
Claim 22
Dependent Claim
41 words
In a method of applying a bone cement to bone implants so as to firmly join the bone implants to the respective skeleton parts of the body, the improvement comprising applying the bioactive composite material of claim 1 to said implants.
Claim 23
Dependent Claim
21 words
In a method of repairing bone, the improvement comprising applying the bioactive composite material of claim 1 as a filling material.
Claim 24
Dependent Claim
38 words
In a method of using a fully polymerized material as bone or tooth prosthetic material, the improvement comprising using the fully polymerized bioactive composite material of claim 1 in the shape of bones or teeth or parts thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-12-25 | 1982-06-26 | 1982-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-12-25 | 1986-06-26 | 1986-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-12-25 | 1990-06-26 | 1990-12-26 | $7700.00 | Window Closed / Lapsed |