US4096321A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process to produce oxazinomycin and intermediates
Assignee: Hoffmann La Roche Inc
•
Filing: 1976-11-22
•
Granted: 1978-06-20
•
Expires: 1996-11-22
Abstract
Abstract A novel synthetic process to produce the antibiotic oxazinomycin is presented along with novel intermediates utilized in said process.
Inventors
- 👤 Manfred Weigele
- 👤 Silvano DeBernardo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:12
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/04; C07D413/00; C07D413/02; C07D413/04; C07H; C07H15/00; C07H15/18; C07H23/00
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
62 words
A compound of the formula ##STR5## wherein R 8 is lower alkyl, R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR6## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR7## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 2
Dependent Claim
62 words
A compound of the formula ##STR5## wherein R 8 is lower alkyl, R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR6## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR7## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 3
Dependent Claim
62 words
A compound of the formula ##STR8## wherein R 8 is lower alkyl, R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR9## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR10## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 4
Dependent Claim
62 words
A compound of the formula ##STR8## wherein R 8 is lower alkyl, R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR9## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR10## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 5
Dependent Claim
57 words
A compound of the formula ##STR11## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR12## wherein R 4 is selected from the grup consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR13## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 6
Dependent Claim
57 words
A compound of the formula ##STR11## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR12## wherein R 4 is selected from the grup consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR13## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 7
Dependent Claim
57 words
A compound of the formula ##STR14## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR15## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR16## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 8
Dependent Claim
57 words
A compound of the formula ##STR14## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR15## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR16## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 9
Dependent Claim
57 words
A compound of the formula ##STR17## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR18## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR19## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 10
Dependent Claim
57 words
A compound of the formula ##STR17## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR18## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR19## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 11
Dependent Claim
57 words
A compound of the formula ##STR20## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR21## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR22## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 12
Dependent Claim
57 words
A compound of the formula ##STR20## wherein R 9 is hydrogen or lower alkyl and R 3 is selected from the group consisting of ##STR21## wherein R 4 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halo and nitro and ##STR22## wherein R 5 , R 6 and R 7 are lower alkyl.
Claim 13
Dependent Claim
26 words
A compound of the formula ##STR23## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 14
Dependent Claim
26 words
A compound of the formula ##STR23## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 15
Dependent Claim
9 words
The compound of claim 7 of the formula ##STR24##
Claim 16
Dependent Claim
26 words
A compound of the formula ##STR25## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 17
Dependent Claim
26 words
A compound of the formula ##STR25## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 18
Dependent Claim
9 words
The compound of claim 9 of the formula ##STR26##
Claim 19
Dependent Claim
26 words
A compound of the formula ##STR27## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 20
Dependent Claim
26 words
A compound of the formula ##STR27## wherein R 9 is hydrogen or lower alkyl and R 5 , R 6 and R 7 are lower alkyl.
Claim 21
Dependent Claim
9 words
The compound of claim 11 of the formula ##STR28##
Claim 22
Dependent Claim
26 words
A compound of the formula ##STR29## wherein R 9 is lower alkyl or hydrogen and R 5 , R 6 and R 7 are lower alkyl.
Claim 23
Dependent Claim
26 words
A compound of the formula ##STR29## wherein R 9 is lower alkyl or hydrogen and R 5 , R 6 and R 7 are lower alkyl.
Claim 24
Dependent Claim
9 words
The compound of claim 13 of the formula ##STR30##
Claim 25
Dependent Claim
18 words
The compound of claim 1 wherein R 3 is ##STR31## and R 8 and R 9 are methyl.
Claim 26
Dependent Claim
18 words
The compound of claim 2 wherein R 3 is ##STR32## and R 8 and R 9 are methyl.
Claim 27
Dependent Claim
15 words
The compound of claim 3 wherein R 3 is ##STR33## and R 9 is methyl.
Claim 28
Dependent Claim
15 words
The compound of claim 4 wherein R 3 is ##STR34## and R 9 is methyl.
References Cited (Backward Citations)
US4043937A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-19 | 1981-12-19 | 1982-06-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-19 | 1985-12-19 | 1986-06-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-19 | 1989-12-19 | 1990-06-20 | $7700.00 | Window Closed / Lapsed |