Cuvette positioning device for optical analytical apparatus

Claim 2

A spectrophotometer for alternately analyzing first and second material samples contained in individual cells including, means for forming an excitation radiation beam for application to a selected one of said samples, means for collecting an emission radiation beam from said selected one of said samples, means for detecting said emission radiation beam, means for positioning said samples in the path of said radiation beam including a cell carrier for supporting said cells in a substantially vertical relationship, said cells comprising elongate cuvettes of generally rectangular cross-section disposed in said cell carrier end-to-end and said cell carrier including a pair of complimentary dimensioned compartments for receiving said generally rectangular cuvettes with each compartment being configured in a manner to facilitate insertion and removal of said cuvette in and from said cell carrier and to facilitate impingement of said excitation radiation beam on, and emission of said emission radiation beam from, said samples, means for mounting said cell carrier in a substantially vertical operating path whereby one cell is disposed in the path of said excitation radiation beam at one position of travel and the other cell is disposed in the path of said excitation radiation beam at another position of travel, and drive means for reciprocating said cell carrier along said vertical operating path to alternately position said cells in said excitation radiation beam path.

Claim 3

The spectrophotometer as defined in claim 1, wherein said excitation beam impinges on each of said samples at an angle of approximately 90° to the path of said emission radiation beam.

Claim 4

The spectrophotometer as defined in claim 1 wherein said compartments are open on two sides to facilitate insertion and removal of said cuvettes in and from said cell carrier.

Claim 5

The spectrophotometer as defined in claim 1 wherein said drive means impart sinusoidal motion to said cell carrier along said defined operating path.

Claim 6

The spectrophotometer as defined in claim 4 wherein said drive means include a drive member operatively engaged to said cell carrier for reciprocation along a vertical axis therewith, and a rotatably driven wheel having a cam radially spaced thereon operatively engaged to a substantially horizontal drive slot on said drive member.

Claim 7

The spectrophotometer as defined in claim 1 wherein said drive means include a drive member mounted for reciprocation along said vertical axis, and said drive member is operatively engaged to said cell carrier by means including a magnet.

Claim 8

The spectrophotometer as defined in claim 1 wherein said cell carrier includes spring means for retaining said cells in position.

Claim 9

The spectrophotometer as defined in claim 1 wherein said drive means include means responsive to the position of said cell carrier along said operating path for generating a control effect indicative of the position thereof for application to external processing circuitry.

Claim 10

A spectrophotometer for optically analyzing first and second material samples contained in individual cells comprising, in combination: means for generating an analytical radiation beam for application to said samples; means for collecting an emission radiation beam from each of said samples; a cell carrier for supporting said cells in vertically aligned relationship, said cell carrier having two compartments, one located above the other, and each being configured in a manner to facilitate insertion and removal of said cells into and out of said compartments and to facilitate impingement of said analytical radiation beam on and collection of said emission radiation beam from each of said samples; means for mounting said cell carrier in a vertical path of reciprocation whereby said cells are individually exposed to said analytical radiation beam as said cell carrier traverses said path; and drive means for reciprocating said cell carrier along said path to alternately expose said cells to said analytical radiation beam.

Claim 11

A spectrophotometer for optically analyzing first and second material samples contained in individual cells comprising, in combination: means for generating an analytical radiation beam for application to said samples; means for collecting an emission radiation beam from each of said samples; a cell carrier for supporting said cells in vertically aligned relationship, said cell carrier having two compartments, one located above the other, and each being configured in a manner to facilitate insertion and removal of said cells into and out of said compartments and to facilitate impingement of said analytical radiation beam on and collection of said emission radiation beam from each of said samples; means for mounting said cell carrier in a vertical path of reciprocation whereby said cells are individually exposed to said analytical radiation beam as said cell carrier traverses said path; and drive means for reciprocating said cell carrier along said path to alternately expose said cells to said analytical radiation beam.

Claim 12

The spectrophotometer as defined in claim 9 wherein said drive means impart sinusoidal motion to said cell carrier.

Claim 13

A spectrofluorometer for analyzing first and second material samples contained in individual cells including means for generating an excitation radiation beam for application to said samples, mean for collecting an emission radiation beam from each of said samples, a detector for analyzing said emission radiation beam received from said samples, means for alternately positioning said samples in said radiation beam including a cell carrier for supporting said cells in a substantially vertical relationship, means for mounting said cell carrier for movement in a substantially vertical operating path whereby said first cell is disposed in said excitation radiation beam at one particular position of travel, and said second cell is disposed in said excitation radiation beam at another position of travel, said cells comprising elongate cuvettes of generally rectangular cross-section disposed in said cell carrier end-to-end, one above the other and said cell carrier including a pair of complementary dimensioned compartments for receiving said generally rectangular cuvettes with each compartment being configured in a manner to facilitate insertion and removal of said cuvettes in and from said cell carrier and to facilitate impingement of said excitation radiation beam on, and emission of said emission radiation beam from said samples, drive means for reciprocating said cell carrier along said operating path to alternately position said first and second cells in said radiation path, and signal processing means for developing an output signal indicative of the variation in characteristics between said samples, said processing means including, in combination: a first storage circuit serially including a first capacitor and a first switching means coupled between said detector and a plane of reference potential; a second storage circuit serially including a second switching means and a second capacitor coupled between the juncture of said first capacitor and said first switching means, and said plane of reference potential; synchronizing means responsive to the position of said cell carrier for selectively closing said first switching means only while said first cell is in said radiation beam, and for selectively closing said second switching means only while said second cell is in said radiation beam; and utilization means including an amplifier coupled to said second capacitor and said plane of reference potential for developing a differential output signal.

Claim 14

A spectrofluorometer for analyzing first and second material samples contained in individual cells including means for generating an excitation radiation beam for application to said samples, mean for collecting an emission radiation beam from each of said samples, a detector for analyzing said emission radiation beam received from said samples, means for alternately positioning said samples in said radiation beam including a cell carrier for supporting said cells in a substantially vertical relationship, means for mounting said cell carrier for movement in a substantially vertical operating path whereby said first cell is disposed in said excitation radiation beam at one particular position of travel, and said second cell is disposed in said excitation radiation beam at another position of travel, said cells comprising elongate cuvettes of generally rectangular cross-section disposed in said cell carrier end-to-end, one above the other and said cell carrier including a pair of complementary dimensioned compartments for receiving said generally rectangular cuvettes with each compartment being configured in a manner to facilitate insertion and removal of said cuvettes in and from said cell carrier and to facilitate impingement of said excitation radiation beam on, and emission of said emission radiation beam from said samples, drive means for reciprocating said cell carrier along said operating path to alternately position said first and second cells in said radiation path, and signal processing means for developing an output signal indicative of the variation in characteristics between said samples, said processing means including, in combination: a first storage circuit serially including a first capacitor and a first switching means coupled between said detector and a plane of reference potential; a second storage circuit serially including a second switching means and a second capacitor coupled between the juncture of said first capacitor and said first switching means, and said plane of reference potential; synchronizing means responsive to the position of said cell carrier for selectively closing said first switching means only while said first cell is in said radiation beam, and for selectively closing said second switching means only while said second cell is in said radiation beam; and utilization means including an amplifier coupled to said second capacitor and said plane of reference potential for developing a differential output signal.

Claim 15

The spectrofluorometer as defined in claim 11 wherein said first and second storage circuits each include a series impedance.

Claim 16

The spectrofluorometer as defined in claim 11, wherein said excitation beam inpinges on each of said samples at an angle of approximately 90° to the path of said emission radiation beam.