Abstract Natural or synthetic rubber surgical elements such as tubing, catheters, drains and gloves are "lubricated" so as to prevent sticking during storage, and permit easier emplacement, such as putting on the gloves by a surgeon or nurse, by applying to the surface of the rubber element A finely divided biodegradable powder consisting essentially of An enzymatically degradable form of poly(N-acetyl-D-glucosamine) selected from the group consisting of Poly[N-acetyl-6-O-(carboxymethyl)-D-glucosamine], Poly[N-acetyl-6-O-(2'-hydroxyethyl)-D-glucosamine], Poly[N-acetyl-6-O-(ethyl)-D-glucosamine], and Poly(N-acetyl-D-glucosamine) itself This powder is readily absorbed by living tissue without deleterious tissue reaction, thus minimizing tissue reaction from the transfer of the powder from the element such as a glove to internal sites in a subject. The gloves may be packaged in a strippable laminate package. The polymers are derived from chitin.
A surgical glove of natural or synthetic rubber having on the surface thereof in a small but lubricity imparting quantity a finely divided biodegradable powder consisting essentially of an enzymatically degradable form of poly(N-acetyl-D-glucosamine) selected from the group consisting of poly[N-acetyl-6-O-(carboxymethyl)-D-glucosamine], poly[N-acetyl-6-O-(2'-hydroxyethyl)-D-glucosamine], poly[N-acetyl-6-O-(ethyl)-D-glucosamine], and poly(N-acetyl-D-glucosamine) itself which form of poly(N-acetyl-D-glucosamine) is slowly enzymatically degraded by contact with body tissues.
Claim 2
Dependent Claim
59 words
A surgical glove of natural or synthetic rubber having on the surface thereof in a small but lubricity imparting quantity a finely divided biodegradable powder consisting essentially of an enzymatically degradable form of poly(N-acetyl-D-glucosamine) selected from the group consisting of poly[N-acetyl-6-O-(carboxymethyl)-D-glucosamine], poly[N-acetyl-6-O-(2'-hydroxyethyl)-D-glucosamine], poly[N-acetyl-6-O-(ethyl)-D-glucosamine], and poly(N-acetyl-D-glucosamine) itself which form of poly(N-acetyl-D-glucosamine) is slowly enzymatically degraded by contact with body tissues.
Claim 3
Dependent Claim
19 words
The glove of claim 1 in which the biodegradable powder has a particle size of 0.5 to 149 microns.
Claim 4
Dependent Claim
26 words
The glove of claim 2 in which the glove and powder are sterile, and the powder is poly[N-acetyl-6-O-(carboxymethyl)-D-glucosamine] which will pass through a 200 mesh screen.
Claim 5
Dependent Claim
26 words
The glove of claim 2 in which the glove and powder are sterile, and the powder is poly[N-acetyl-6-O-(2'-hydroxyethyl)-D-glucosamine] which will pass through a 200 mesh screen.
Claim 6
Dependent Claim
26 words
The glove of claim 2 in which the glove and powder are sterile, and the powder is poly[N-acetyl-6-O-(ethyl)-D-glucosamine] which will pass through a 200 mesh screen.
Claim 7
Dependent Claim
26 words
The glove of claim 2 in which the glove and powder are sterile, and the powder is poly(N-acetyl-D-glucosamine) which will pass through a 200 mesh screen.