US4057394A
Expired / Lapsed
US
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Test device and method for determining blood hemoglobin
Assignee: Bayer Corp
•
Filing: 1976-05-24
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Granted: 1977-11-08
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Expires: 1996-05-24
Abstract
Abstract A test device and method are provided for determining the hemoglobin content of blood. The test device comprises a substantially opaque light reflecting matrix having a refractive index significantly different from the refractive index of blood. In use, a test sample of blood is contacted with the matrix of said test device and the light reflectance therefrom is measured as an indication of the quantitative amount of hemoglobin present in said sample.
Inventors
- 👤 Marvin Alden Genshaw
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:03
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
67 words
A method for determining the hemoglobin content of blood, which comprises contacting a test device with a sample of blood and measuring light at a wavelength of between about 300 and about 620 nanometers which is reflected from said test device, wherein said test device comprises a substantially opaque, light reflective, blood absorbent matrix having a refractive index of less than about 1.0 or above about 1.7.
Claim 2
Independent Claim
67 words
A method for determining the hemoglobin content of blood, which comprises contacting a test device with a sample of blood and measuring light at a wavelength of between about 300 and about 620 nanometers which is reflected from said test device, wherein said test device comprises a substantially opaque, light reflective, blood absorbent matrix having a refractive index of less than about 1.0 or above about 1.7.
Claim 3
Dependent Claim
31 words
The method of claim 1 in which the light reflected from said test device is measured within about 0.5 to about 3 minutes after the blood sample contacts said test device.
Claim 4
Dependent Claim
174 words
A test device for determining the hemaglobin content of a blood sample to an accuracy of about ± 0.5 grams of hemaglobin per 100 milliliters of the blood sample by a reflected light measurement made at a wavelength between about 300 and about 620 nanometers within about 0.5 and about 3 minutes after the blood sample is applied to said test device, which test device comprises a substantially opaque, light reflective, blood absorbent matrix having a refractive index of less than about 1.0 or above about 1.7 which is prepared by incorporating a blood absorbent member with a substantially opaque light reflecting substance selected from the class of white or light colored materials consisting of powdered metals, metallic carbonates, metallic oxide and metallic sulfides which are insoluble in and unreactive in said blood sample at a concentration providing a light reflectance of between about 30 and 70 percent of the incident light when the matrix is saturated with said blood sample, said test device including means for venting air from said blood absorbent matrix.
Claim 5
Dependent Claim
174 words
A test device for determining the hemaglobin content of a blood sample to an accuracy of about ± 0.5 grams of hemaglobin per 100 milliliters of the blood sample by a reflected light measurement made at a wavelength between about 300 and about 620 nanometers within about 0.5 and about 3 minutes after the blood sample is applied to said test device, which test device comprises a substantially opaque, light reflective, blood absorbent matrix having a refractive index of less than about 1.0 or above about 1.7 which is prepared by incorporating a blood absorbent member with a substantially opaque light reflecting substance selected from the class of white or light colored materials consisting of powdered metals, metallic carbonates, metallic oxide and metallic sulfides which are insoluble in and unreactive in said blood sample at a concentration providing a light reflectance of between about 30 and 70 percent of the incident light when the matrix is saturated with said blood sample, said test device including means for venting air from said blood absorbent matrix.
Claim 6
Dependent Claim
30 words
The test device according to claim 3 wherein said air venting means comprises an air venting layer interposed in laminate relation between the blood absorbent matrix and a carrier member.
Claim 7
Dependent Claim
16 words
A test device according to claim 3 wherein the opaque light reflecting substance is titanium dioxide.
Claim 8
Dependent Claim
24 words
A test device according to claim 3 wherein the blood absorbent member is also incorporated with a water soluble binder and a wetting agent.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-07 | 1981-05-09 | 1981-11-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-07 | 1985-05-09 | 1985-11-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-07 | 1989-05-09 | 1989-11-08 | $7700.00 | Window Closed / Lapsed |