US4049803A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Augmentation of blood levels of aspirin
Assignee: Bristol Myers Co
•
Filing: 1976-04-26
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Granted: 1977-09-20
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Expires: 1996-04-26
Abstract
Abstract The normal dosage of 10 grains (648 mg.) of aspirin, when combined with about 5 to 15, preferably about 10, grains of acetaminophen, yields increased blood levels of unhydrolyzed aspirin shortly and for extended periods after oral ingestion; a small addition of caffeine enables attainment of still higher blood levels of aspirin.
Inventors
- 👤 Val F. Cotty
- 👤 Francis J. Sterbenz
- 👤 Kenneth J. Melman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:09
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/60; A61K31/618; A61K31/621
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
58 words
As a composition of matter, a dose of a mixture containing about 10 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
Claim 2
Dependent Claim
58 words
As a composition of matter, a dose of a mixture containing about 10 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
Claim 3
Dependent Claim
30 words
A composition according to claim 1 in which said dose takes the form of two tablets each containing about 5 grains of acetaminophen and about 5 grains of acetylsalicylic acid.
Claim 4
Dependent Claim
30 words
A composition according to claim 1 in which said dose takes the form of two capsules each containing about 5 grains of acetaminophen and about 5 grains of acetylsalicylic acid.
Claim 5
Dependent Claim
17 words
A composition according to claim 1 also containing from about 0.5 grains to 2 grains of caffeine.
Claim 6
Dependent Claim
58 words
As a composition of matter, a dose of a mixture containing about 5 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
Claim 7
Dependent Claim
58 words
As a composition of matter, a dose of a mixture containing about 5 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
Claim 8
Dependent Claim
29 words
A composition according to claim 5 in which said dose takes the form of two capsules each containing about 21/2 grains of acetaminophen and 5 grains of acetylsalicylic acid.
Claim 9
Dependent Claim
37 words
A compressed tablet comprising a homogeneous mixture of about 5 grains of acetaminophen and 5 grains of acetylsalicylic acid, said tablet being adapted for substantially concurrent release of said acetaminophen and said acetylsalicylic acid to the body.
Claim 10
Dependent Claim
37 words
A compressed tablet comprising a homogeneous mixture of about 5 grains of acetaminophen and 5 grains of acetylsalicylic acid, said tablet being adapted for substantially concurrent release of said acetaminophen and said acetylsalicylic acid to the body.
Claim 11
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 1.
Claim 12
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 2.
Claim 13
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 3.
Claim 14
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 4.
Claim 15
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 5.
Claim 16
Dependent Claim
28 words
A method for augmenting the blood levels of acetylsalicylic acid in animals which comprises orally administering to said animals a dosage quantity of the composition of claim 6.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-19 | 1981-03-21 | 1981-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-19 | 1985-03-21 | 1985-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-19 | 1989-03-21 | 1989-09-20 | $7700.00 | Window Closed / Lapsed |