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US4041152A Expired / Lapsed US ⏱️ 0.0 years remaining

Pharmaceutical formulation of interferon insolubilized by fixation on a support

Assignee: Individual
•
Filing: 1974-07-22
•
Granted: 1977-08-09
•
Expires: 1994-07-22
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Abstract

Abstract A pharmaceutical product consists of interferon which has been rendered insoluble by being coupled to a support, such as sepharose.

Inventors

  • 👤 Charles Chany
  • 👤 Brigitte Galliot
  • 👤 Marie-Josephe Chevalier
  • 👤 Helmut Ankel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 11:41
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; C07K14/555; A; A61; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/61; A61K38/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 39 words
A pharmaceutical product comprising an effective amount of interferon rendered insoluble by fixation by way of covalent bonds on a previously activated support selected from the group consisting of agarose, dextran, levan, mannan, pectin, xylan, galactan, glycerol-pectate and heparin.
Claim 2
Dependent Claim 39 words
A pharmaceutical product comprising an effective amount of interferon rendered insoluble by fixation by way of covalent bonds on a previously activated support selected from the group consisting of agarose, dextran, levan, mannan, pectin, xylan, galactan, glycerol-pectate and heparin.
Claim 3
Dependent Claim 47 words
A process for the preparation of the pharmaceutical product according to claim 1 which comprises activating the support by means of the Porath process and then reacting the activated support with the interferon to provide a pharmaceutical product having interferon fixed by covalent bonds to said support.
Claim 4
Dependent Claim 15 words
A pharmaceutical composition comprising the product of claim 1 in association with a pharmaceutical carrier.
Claim 5
Dependent Claim 15 words
A pharmaceutical product comprising interferon fixed by electrostatic bonds on a support comprising concavallin A.
Claim 6
Dependent Claim 15 words
A pharmaceutical product comprising interferon fixed by electrostatic bonds on a support comprising concavallin A.
Claim 7
Dependent Claim 47 words
A process for the preparation of the pharmaceutical product according to claim 4 which comprises mixing of a solution of interferon with a suspension of concavallin A in M.E.M. medium, the contact being maintained for a sufficient period of time to couple the maximum amount of interferon.
Claim 8
Dependent Claim 15 words
A pharmaceutical composition comprising the product of claim 1 in association with a pharmaceutical carrier.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-08-08 1981-02-07 1981-08-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-08-08 1985-02-07 1985-08-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-08-08 1989-02-07 1989-08-09 $7700.00 Window Closed / Lapsed

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