US4016303A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of flocking blood-contacting surfaces on artificial implant devices
Assignee: Government of the United States of America
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Filing: 1975-08-06
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Granted: 1977-04-05
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Expires: 1995-08-06
Abstract
Abstract Blood-contacting surfaces of artificial implant devices which have been flocked with fibers of a blood-compatible polymeric material to promote formation of a stable and viable biological lining when the device has been implanted in a living body, are treated to strengthen the bonds between the fibers and the substrate surface and to interlock the fibers with each other so as to substantially reduce the possibility of fiber separation and release from the substrate surface into the blood stream. The treatment is effected by applying to the flocked surface a dilute solution of an adhesive material in a solvent therefor, the content of the adhesive material in the treating solution being controlled so as to be sufficient to coat the fibers only at their points of contact with each other and with the substrate surface. When the solvent is thereafter evaporated from the substrate surface, secondary bonds of adhesive material are formed at such points of contact, leaving the fibers otherwise uncoated so as not to interfere with their biological lining formation-promoting properties.
Inventors
- 👤 Victor L. Poirier
- 👤 John T. Keiser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:50
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/0077; A61L; A61L27/00; A61L27/14; A61L27/18; Y; Y10; Y10S; Y10S623/00; Y10S623/901; Y10T; Y10T428/00; Y10T428/23907; Y10T428/23943
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
218 words
In a method for the manufacture of an artificial implant device adapted to be implanted in blood-contacting position in the body of a living creature such as a human being, said method including the steps of flocking the bloodcontacting surface of said device with fibers of a bloodcompatible polymeric material by first applying to said surface a coating of blood-compatible adhesive material and thereafter applying said fibers to the adhesive-coated surface so as to adhesively secure said fibers to said surface, the improvement whereby the bonds between said fibers and said surface are strengthened and said fibers are interlocked with each other so as to substantially reduce the possibility of fiber separation and release from said surface when said device is in implanted position, comprising the steps of applying to said flocked surface a dilute solution of said adhesive material in a solvent therefor whereby said adhesive material is preferentially attracted by capillary action to the points of contact of said fibers with each other and with said surface, the content of said adhesive material in said solution being sufficient to coat said fibers only at said points of contact, and thereafter evaporating said solvent from said surface to thereby form secondary bonds of said adhesive material at said points of contact and leave said fibers otherwise uncoated.
Claim 2
Dependent Claim
218 words
In a method for the manufacture of an artificial implant device adapted to be implanted in blood-contacting position in the body of a living creature such as a human being, said method including the steps of flocking the bloodcontacting surface of said device with fibers of a bloodcompatible polymeric material by first applying to said surface a coating of blood-compatible adhesive material and thereafter applying said fibers to the adhesive-coated surface so as to adhesively secure said fibers to said surface, the improvement whereby the bonds between said fibers and said surface are strengthened and said fibers are interlocked with each other so as to substantially reduce the possibility of fiber separation and release from said surface when said device is in implanted position, comprising the steps of applying to said flocked surface a dilute solution of said adhesive material in a solvent therefor whereby said adhesive material is preferentially attracted by capillary action to the points of contact of said fibers with each other and with said surface, the content of said adhesive material in said solution being sufficient to coat said fibers only at said points of contact, and thereafter evaporating said solvent from said surface to thereby form secondary bonds of said adhesive material at said points of contact and leave said fibers otherwise uncoated.
Claim 3
Dependent Claim
11 words
The method of claim 1, wherein said fibers are polyester fibers.
Claim 4
Dependent Claim
12 words
The method of claim 2, wherein said fibers are polyethylene terephthalate fibers.
Claim 5
Dependent Claim
26 words
The method of claim 1, wherein said dilute solution of adhesive material is applied to said flocked surface by dipping said flocked surface into said solution.
Claim 6
Dependent Claim
12 words
The method of claim 1, wherein said adhesive material is a polyurethane.
Claim 7
Dependent Claim
11 words
The method of claim 5, wherein said solvent is methylethyl ketone.
Claim 8
Dependent Claim
21 words
The method of claim 5, wherein the polyurethane content in said dilute solution is from 5 to 20 percent by volume.
Claim 9
Dependent Claim
18 words
The method of claim 7, wherein the polyurethane content in said dilute solution is 10 percent by volume.
Claim 10
Dependent Claim
49 words
The method of claim 1, wherein said fibers are provided with an anti-agglomerating surface finish to facilitate their handling during the flocking operation, and said finish is removed from said fibers after the flocking operation and prior to applying said dilute solution of adhesive material to said flocked surface.
References Cited (Backward Citations)
US3098755A
Cited
US3956553A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-04-04 | 1980-10-04 | 1981-04-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-04-04 | 1984-10-04 | 1985-04-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-04-04 | 1988-10-04 | 1989-04-05 | $7700.00 | Window Closed / Lapsed |