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US3986962A Expired / Lapsed US ⏱️ 0.0 years remaining

Novel assembly for separating blood

Assignee: Becton Dickinson and Co
•
Filing: 1975-07-10
•
Granted: 1976-10-19
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Expires: 1995-07-10
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Abstract

Abstract Disclosure is made of an improved assembly for the collection, separation and isolation of serum or plasma from blood without subjecting the desired serum or plasma to contamination by exposure to the atmosphere and which utilizes a thixotropic barrier material to effect the isolation. A representative embodiment of the improved assembly comprises an air-evacuated collection chamber, a self-sealing airtight elastomeric closure for the container which is penetrable by a blood bearing cannula and a thixotrope having a specific gravity of from about 1.03 to about 1.09, held in a specially constructed reservoir positioned within the closure member and in communication with the air-evacuated chamber.

Inventors

  • 👤 Stephen B. Kessler

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 13:50
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/491; B; B01; B01D; B01D21/00; B01D21/26; B01D21/262; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5021; B01L3/50215; B01D2221/00; B01D2221/10

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 204 words
An assembly for the collection, separation and isolation of serum or plasma from blood, which comprises; a. a tubular container having an open end and which defines a blood collection chamber; b. a self-sealing, cannula-penetrable, elastomeric closure member hermetically sealing said open end; c. a recess in the inner surface of said closure member; d. a thixotrope barrier dispenser secured in said recess, said dispenser comprising; i. a tubular body fabricated of hemorepellant material and having an open lower end which defines a thixotrope reservoir, said open lower end being insufficient in size to permit pasage of said thixotrope under the force of one gravity but of sufficient size to permit passage of said thixotrope when the thixotrope is subjected to a centrifugal force in substantial excess of one gravity; and ii. a conduit passing through the center of said reservoir and providing communication between the adjacent closure member and the blood collection chamber said conduit extending partially into said blood collection chamber; and e. a thixotrope sealant disposed in said reservoir, said thixotrope having a specific gravity within the range of from about 1.03 to about 1.09; said assembly being air-evacuated to provide at least a partial vacuum in said blood collection chamber.
Claim 2
Dependent Claim 204 words
An assembly for the collection, separation and isolation of serum or plasma from blood, which comprises; a. a tubular container having an open end and which defines a blood collection chamber; b. a self-sealing, cannula-penetrable, elastomeric closure member hermetically sealing said open end; c. a recess in the inner surface of said closure member; d. a thixotrope barrier dispenser secured in said recess, said dispenser comprising; i. a tubular body fabricated of hemorepellant material and having an open lower end which defines a thixotrope reservoir, said open lower end being insufficient in size to permit pasage of said thixotrope under the force of one gravity but of sufficient size to permit passage of said thixotrope when the thixotrope is subjected to a centrifugal force in substantial excess of one gravity; and ii. a conduit passing through the center of said reservoir and providing communication between the adjacent closure member and the blood collection chamber said conduit extending partially into said blood collection chamber; and e. a thixotrope sealant disposed in said reservoir, said thixotrope having a specific gravity within the range of from about 1.03 to about 1.09; said assembly being air-evacuated to provide at least a partial vacuum in said blood collection chamber.
Claim 3
Dependent Claim 10 words
The assembly of claim 1 wherein said container is glass.
Claim 4
Dependent Claim 14 words
The assembly of claim 1 wherein said thixotrope has a specific gravity of 1.06.
Claim 5
Dependent Claim 17 words
The assembly of claim 1 wherein said thixotrope has a viscosity of at least about 30,000 centistokes.

References Cited (Backward Citations)

GB399702A Cited
US2584397A Cited
US2608972A Cited
US2812231A Cited
US3139121A Cited
US3608550A Cited
US3780935A Cited
US3852194A Cited
US3920557A Cited
US3901219A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-10-19 1980-04-19 1980-10-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-10-19 1984-04-19 1984-10-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-10-19 1988-04-19 1988-10-19 $7700.00 Window Closed / Lapsed

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