US3980766A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Orally administered drug composition for therapy in the treatment of narcotic drug addiction
Assignee: Phoenix Pharmaceuticals Inc
•
Filing: 1975-01-27
•
Granted: 1976-09-14
•
Expires: 1995-01-27
Abstract
Abstract Drugs which are suitable for such therapy in treatment of narcotic drug addiction by oral use, e.g., methadone, are formulated to prevent injection abuse through concentration of the active component in aqueous solution by incorporating in a solid dosage or tablet form of such drug an ingestible solid having thickening properties which causes rapid increase in viscosity upon concentration of an aqueous solution thereof.
Inventors
- 👤 Irving F. Shaw
- 👤 Jerome Berk
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:32
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K31/00; A61K31/13; A61K31/135; A61K31/137
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
91 words
A solid composition for the oral treatment of narcotic addiction which is dispersible for dissolution before ingestion, said composition comprising: a. an effective amount of methadone or its acid salts, and b. an ingestible solid in a weight ratio of 10:1 to 40:1 per part of methadone in an amount sufficient to cause a rapid increase in viscosity during evaporation of an aqueous solution of the composition, wherein said ingestible solid is lactose, sucrose, mannitol, sorbitol, starch, microcrytalline cellulose, sodium carboxymethyl cellulose, methylcellulose ethylcellulose, carrageenin, gum tragacanth, gum acacia or polyvinylpyrrolidone.
Claim 2
Dependent Claim
91 words
A solid composition for the oral treatment of narcotic addiction which is dispersible for dissolution before ingestion, said composition comprising: a. an effective amount of methadone or its acid salts, and b. an ingestible solid in a weight ratio of 10:1 to 40:1 per part of methadone in an amount sufficient to cause a rapid increase in viscosity during evaporation of an aqueous solution of the composition, wherein said ingestible solid is lactose, sucrose, mannitol, sorbitol, starch, microcrytalline cellulose, sodium carboxymethyl cellulose, methylcellulose ethylcellulose, carrageenin, gum tragacanth, gum acacia or polyvinylpyrrolidone.
Claim 3
Dependent Claim
14 words
The composition of claim 1 which further contains NHCO 3 as a precipitating agent.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-14 | 1980-03-15 | 1980-09-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-14 | 1984-03-15 | 1984-09-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-14 | 1988-03-15 | 1988-09-14 | $7700.00 | Window Closed / Lapsed |