US3975512A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Non-toxic brominated perfluorocarbons radiopaque agents
Assignee: University of Illinois System
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Filing: 1974-08-26
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Granted: 1976-08-17
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Expires: 1994-08-26
Abstract
Abstract Non-toxic bromofluorocarbon radiopaque agents are disclosed. Certain monobrominated acyclic fluorocarbons, e.g., CF3(CF2)6CF2Br, are improved non-toxic radiopaque agents useful in diagnostic roentgenology, for example in visualizing the gastrointestinal tract, the tracheobronchial tree, the alveolar spaces or parenchyma of the lung, the spleen, the urinary bladder and ureters, the common bile duct and its radicals, the pancreatic ducts, the blood vessels, etc.
Inventors
- 👤 David M. Long, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:29
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/04; A61K49/0433; A61K49/0447; A61K49/0461
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
35 words
In a process for radiologically examining a part of the body of an animal, the improvement comprising contacting said body part with an effective amount of a radiopaque agent comprising a non-toxic monobrominated acyclic perfluorocarbon.
Claim 2
Dependent Claim
35 words
In a process for radiologically examining a part of the body of an animal, the improvement comprising contacting said body part with an effective amount of a radiopaque agent comprising a non-toxic monobrominated acyclic perfluorocarbon.
Claim 3
Dependent Claim
22 words
The process of claim 1 wherein said radiopaque agent comprises a perfluoroalkyl bromide having 6 to 8 carbon atoms in the molecule.
Claim 4
Dependent Claim
19 words
The process of claim 1 wherein said radiopaque agent is CF 3 (CF 2 ) 6 CF 2 Br.
Claim 5
Dependent Claim
18 words
The process of claim 1 wherein said radiopaque agent is administered in the form of an aqueous emulsion.
Claim 6
Dependent Claim
17 words
The process of claim 1 wherein said radiopaque agent is administered in the form of an aerosol.
Claim 7
Dependent Claim
12 words
The process of claim 1 wherein said body part is the spleen.
Claim 8
Dependent Claim
13 words
The process of claim 1 wherein said body part is the gastrointestinal tract.
Claim 9
Dependent Claim
16 words
The process of claim 1 wherein said body part is the tracheobronchial tree and the lungs.
Claim 10
Dependent Claim
26 words
A non-toxic radiopaque emulsion consisting essentially of an aqueous phase, an effective amount of a monobrominated acyclic perfluorocarbon and a minor amount of an emulsifying agent.
Claim 11
Dependent Claim
26 words
A non-toxic radiopaque emulsion consisting essentially of an aqueous phase, an effective amount of a monobrominated acyclic perfluorocarbon and a minor amount of an emulsifying agent.
Claim 12
Dependent Claim
19 words
The emulsion of claim 9 wherein said perfluorocarbon is a perfluoroalkyl bromide having 6-8 carbon atoms in the molecule.
Claim 13
Dependent Claim
18 words
The emulsion of claim 10 wherein said perfluorocarbon is CF 3 (CF 2 ) 6 CF 2 Br.
Claim 14
Dependent Claim
33 words
The emulsion of claim 9 wherein said perfluorocarbon is present in a concentration in the range from about 1 to about 12 parts by weight for each part by weight of aqueous phase.
Claim 15
Dependent Claim
13 words
The emulsion of claim 9 wherein said aqueous phase comprises lactated Ringer's Solution.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-17 | 1980-02-16 | 1980-08-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-17 | 1984-02-16 | 1984-08-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-17 | 1988-02-16 | 1988-08-17 | $7700.00 | Window Closed / Lapsed |