US3975398A
Expired / Lapsed
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9-Substituted 3-aminocarbazole compounds
Assignee: Roche Diagnostics GmbH
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Filing: 1974-07-10
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Granted: 1976-08-17
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Expires: 1994-07-10
Abstract
Abstract Novel 3-aminocarbazole compounds of the formula: ##SPC1## Wherein X is hydrogen or halogen, Y is oxygen or represents two hydrogen atoms; and R 1 and R 2 , which can be the same or different, are hydrogen, lower alkyl or hydroxyalkyl or amino; and n is 1 or 2, with the proviso that when n is 2, X, Y, R 1 and R 2 cannot all be hydrogen atoms, As well as the salts thereof with inorganic and organic acids; are outstandingly effective indicators for the determination of glucose and provide stable compositions for such glucose determination.
Inventors
- 👤 Wolfgang Werner
- 👤 Peter Vogel
- 👤 Hugo Tiedemann
- 👤 Werner Guthlein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:25
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; C07; C07D; C07D209/00; C07D209/56; C07D209/80; C07D209/82; C07D209/88; C12Q1/54; C12Q2326/00; C12Q2326/10; C12Q2326/14; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/81
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
85 words
9-Substituted 3-aminocarbazole compound of the formula: ##SPC6## wherein X is hydrogen or halogen, Y is oxygen or represents two hydrogen atoms; and R 1 and R 2 , which can be the same or different, are hydrogen, lower alkyl or hydroxyalkyl of up to 6 carbon atoms, or amino; and n is 1 or 2, with the proviso that when n is 2, X, Y, R 1 and R 2 cannot all be hydrogen atoms, or a salt thereof with an inorganic or organic acid.
Claim 2
Dependent Claim
85 words
9-Substituted 3-aminocarbazole compound of the formula: ##SPC6## wherein X is hydrogen or halogen, Y is oxygen or represents two hydrogen atoms; and R 1 and R 2 , which can be the same or different, are hydrogen, lower alkyl or hydroxyalkyl of up to 6 carbon atoms, or amino; and n is 1 or 2, with the proviso that when n is 2, X, Y, R 1 and R 2 cannot all be hydrogen atoms, or a salt thereof with an inorganic or organic acid.
Claim 3
Dependent Claim
12 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein X is hydrogen.
Claim 4
Dependent Claim
12 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein X is halogen.
Claim 5
Dependent Claim
12 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein Y is oxygen.
Claim 6
Dependent Claim
14 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein Y represents two hydrogen atoms.
Claim 7
Dependent Claim
21 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein at least one of R 1 and R 2 is lower alkyl.
Claim 8
Dependent Claim
20 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein at least one of R 1 and R 2 is hydroxyalkyl.
Claim 9
Dependent Claim
20 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein at least one of R 1 and R 2 is amino.
Claim 10
Dependent Claim
28 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein n is 2 and at least one of X, Y, R 1 and R 2 is other than hydrogen.
Claim 11
Dependent Claim
18 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein X is halogen and Y represents two hydrogen atoms.
Claim 12
Dependent Claim
16 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein X is hydrogen and n is 1.
Claim 13
Dependent Claim
27 words
9-Substituted 3-aminocarbazole compound as claimed in claim 1 wherein said compound is selected from the group consisting of 9-(Carbamidomethyl)-3-aminocarbazole; 9-(β-Dimethylaminoethyl)-3-aminocarbazole; 9-(β-Dimethylaminoethyl)-6-chloro-3-aminocarbazole; 9-(β-Carbohydrazidoethyl (-3-aminocarbazole; 9-(β-Hydroxyethylaminocarbonylethyl)-3-aminocarbazole; 9-(γ-Dimethylaminopropyl)-3-aminocarbazole; and 9-(γ-Dimethylaminopropyl)-6-chloro-3-aminocarbazole.
References Cited (Backward Citations)
US3822285A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-17 | 1980-02-16 | 1980-08-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-17 | 1984-02-16 | 1984-08-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-17 | 1988-02-16 | 1988-08-17 | $7700.00 | Window Closed / Lapsed |