US3899296A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Whole blood analysis rotor for a multistation dynamic photometer
Assignee: United States Department of Energy
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Filing: 1974-07-17
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Granted: 1975-08-12
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Expires: 1994-07-17
Abstract
Abstract A rotor for performing photometric analyses using whole blood samples. Following static loading of a gross blood sample in the rotor the red blood cells in the gross sample are centrifugally separated from the plasma and measured subvolumes of plasma distributed to respective sample analysis cuvettes positioned in an annular array about the rotor periphery. Means for adding reagents to the respective cuvettes are also described.
Inventors
- 👤 James C Mailen
- 👤 Wayne F Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:22
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/01; G01N21/03; G01N21/07; B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/502738; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0409; B01L2400/043; B01L2400/06; B01L2400/0605; B01L2400/0616; B01L2400/0633
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
158 words
AN IMPROVED ROTOR FOR A PHOTOMERTIC SOLUTION ANALYZER OF THE ROTARY CUVETTE TYPE SUITABLE FOR USE IN ANALYZING WHOLE BLOOD SAMPLES COMPRISING A GENERALLY DISK-SHAPED MEMBER A. A PLURALITY OF SAMPLE ANALYSIS CUVETTES DISPOSED IN A CIRCULAR ARRAY FOR RECEIVING LIQUID SAMPLES AND REAGENTS, SAID DISK-SHAPED MEMBER HAVING TRANSPARENT ALLS ADJACENT SAID SAMPLE ANALYSIS CUVETTES FOR PERMITTING THE PASSAGEWAY OF LIGHT THERETHROUGH, B. A CENTRALLY LOCATED STRATIC LOADING CHAMBER HAVING A LOADING PORT FOR RECEIVING GROSS WHOLE BLOOD SAMPLES, C. A CENTRAL FLUID TRANSFER CAVITY IN OPEN COMMUNICATION WITH THE OUTSIDE OF SAID DISK-SHAPED MEMBER, D. A CONTINUOUS ANNULUS POSITIONED ON A RADIUS INTERMEDIATE SAID CUVETTES AND SAID STATIC LOADING CHAMBER, E. AT LEAST ONE FIRST PASSAGEWAY COMMUNICATING BETWEEN SAID ANNULUS AND SAID STATIC LOADING CHAMBER, F. AT LEAST ONE OVERFLOW CHAMBER POSITIONED INTERMEDIATE SAID ANNULUS AND SAID STATIC LOADING CHAMBER, G. AT LEAST ONE SECOND PASSAGEWAY COMMUNICATING BETWEEN SAID ANNULUS AND SAID AT LEAST ONE OVERFLOW CHAMBER,
Claim 2
Dependent Claim
158 words
AN IMPROVED ROTOR FOR A PHOTOMERTIC SOLUTION ANALYZER OF THE ROTARY CUVETTE TYPE SUITABLE FOR USE IN ANALYZING WHOLE BLOOD SAMPLES COMPRISING A GENERALLY DISK-SHAPED MEMBER A. A PLURALITY OF SAMPLE ANALYSIS CUVETTES DISPOSED IN A CIRCULAR ARRAY FOR RECEIVING LIQUID SAMPLES AND REAGENTS, SAID DISK-SHAPED MEMBER HAVING TRANSPARENT ALLS ADJACENT SAID SAMPLE ANALYSIS CUVETTES FOR PERMITTING THE PASSAGEWAY OF LIGHT THERETHROUGH, B. A CENTRALLY LOCATED STRATIC LOADING CHAMBER HAVING A LOADING PORT FOR RECEIVING GROSS WHOLE BLOOD SAMPLES, C. A CENTRAL FLUID TRANSFER CAVITY IN OPEN COMMUNICATION WITH THE OUTSIDE OF SAID DISK-SHAPED MEMBER, D. A CONTINUOUS ANNULUS POSITIONED ON A RADIUS INTERMEDIATE SAID CUVETTES AND SAID STATIC LOADING CHAMBER, E. AT LEAST ONE FIRST PASSAGEWAY COMMUNICATING BETWEEN SAID ANNULUS AND SAID STATIC LOADING CHAMBER, F. AT LEAST ONE OVERFLOW CHAMBER POSITIONED INTERMEDIATE SAID ANNULUS AND SAID STATIC LOADING CHAMBER, G. AT LEAST ONE SECOND PASSAGEWAY COMMUNICATING BETWEEN SAID ANNULUS AND SAID AT LEAST ONE OVERFLOW CHAMBER,
Claim 3
Dependent Claim
20 words
The improved rotor of claim 1 wherein said annulus and said first, second, third and connecting passageways are capillary sized.
Claim 4
Dependent Claim
21 words
The improved rotor of claim 1 wherein said second and third segments of said third passageways define a preselected sample volume.
Claim 5
Dependent Claim
50 words
The improved rotor of claim 1 wherein said magnetically actuated ball trap valve includes a radially oriented ball traverse chamber and a ball of magnetic material disposed within said ball traverse chamber; the centrifugal end of each of said ball traverse chamber being in communication with a respective connecting passageway.
Claim 6
Dependent Claim
48 words
The improved rotor of claim 1 wherein said means for injecting reagents into said sample analysis cuvettes includes a static reagent loading chamber disposed centripetally to each cuvette, and a radially-extending reagent transfer passageway communicating between the centrifUgal end of each reagent loading chamber and a respective cuvette.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-08-11 | 1979-02-10 | 1979-08-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-08-11 | 1983-02-10 | 1983-08-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-08-11 | 1987-02-10 | 1987-08-12 | $7700.00 | Window Closed / Lapsed |