Patent US2193361A successfully refreshed from Google Patents.
US3886947A
Expired / Lapsed
US
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Non-thrombogenic catheter
Assignee: Boston Scientific Scimed Inc
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Filing: 1973-04-13
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Granted: 1975-06-03
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Expires: 1993-04-13
Abstract
Abstract A catheter suitable for insertion into veins and arteries has an outer surface which is antithrombogenic. One such surface is acidic and is partially neutralized with metallic ions. A catheter in accordance with the present invention is nonthrombogenic and is essentially free of tendency to cause thrombosis, thrombophlebitis or periphlebitis.
Inventors
- 👤 Philip N Sawyer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 16:30
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/06; A61L33/064; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31855; Y10T428/31909; Y10T428/31928
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
109 words
A CATHETER SUITABLE FOR INTRODUCTION OF MONITORING DEVICES AND OF SOLUTION OF FOODS, DRUGS AND CONTRAST MEDIA INTO VEINS AND ARTERIES, AND HAVING NO MORE THAN NEGLIGIBLE TENDENCY TO DEPOSIT THROMBUS OR CAUSE THROMOBOSIS, THROMOBOPHLEBITIS, PERIPHLEBITIS OR FIBROSIS, COMPRISING A TUBULAR STRUCTURE SUITABLE FOR INSERTION INTO A NATURAL OR ARTIFICIAL OPENING IN A BODY, SAID TUBULAR STRUCTURE INCLUDING AN OUTER SURFACE CONSISTING OF AN ACIDIC COPOLYMER PARTIALLY NEUTRALIZED WITH SODIUM OR POTASSIUM SO THAT ON INTRAVASCULAR INSERTION OF SAID CATHETER THE OUTER SURFACE OF SAID CATHETER BECOMES NEGATIVELY CHARGED AS THE RESULT OF RELEASE OF POSITIVE NA+ OR K+ IONS INTO THE ENVIRONMENT, SAID NEGATIVELY CHARGED SURFACE BEING NONTHROMBOGENIC.
Claim 2
Dependent Claim
109 words
A CATHETER SUITABLE FOR INTRODUCTION OF MONITORING DEVICES AND OF SOLUTION OF FOODS, DRUGS AND CONTRAST MEDIA INTO VEINS AND ARTERIES, AND HAVING NO MORE THAN NEGLIGIBLE TENDENCY TO DEPOSIT THROMBUS OR CAUSE THROMOBOSIS, THROMOBOPHLEBITIS, PERIPHLEBITIS OR FIBROSIS, COMPRISING A TUBULAR STRUCTURE SUITABLE FOR INSERTION INTO A NATURAL OR ARTIFICIAL OPENING IN A BODY, SAID TUBULAR STRUCTURE INCLUDING AN OUTER SURFACE CONSISTING OF AN ACIDIC COPOLYMER PARTIALLY NEUTRALIZED WITH SODIUM OR POTASSIUM SO THAT ON INTRAVASCULAR INSERTION OF SAID CATHETER THE OUTER SURFACE OF SAID CATHETER BECOMES NEGATIVELY CHARGED AS THE RESULT OF RELEASE OF POSITIVE NA+ OR K+ IONS INTO THE ENVIRONMENT, SAID NEGATIVELY CHARGED SURFACE BEING NONTHROMBOGENIC.
Claim 3
Dependent Claim
109 words
A catheter suitable for introduction of monitoring devices and of solutions of foods, drugs and contrast media into veins and arteries, and having no more than negligible tendency to deposit thrombus or cause thrombosis, thrombophlebitis, periphlebitis or fibrosis, comprising a tubular structure suitable for insertion into a natural or artificial opening in a body, said tubular structure including an outer surface consisting of an acidic copolymer partially neutralized with sodium or potassium so that on intravascular insertion of said catheter the outer surface of said catheter becomes negatively charged as the result of release of positive Na or K ions into the environment, said negatively charged surface being non-thrombogenic.
Claim 4
Dependent Claim
109 words
A catheter suitable for introduction of monitoring devices and of solutions of foods, drugs and contrast media into veins and arteries, and having no more than negligible tendency to deposit thrombus or cause thrombosis, thrombophlebitis, periphlebitis or fibrosis, comprising a tubular structure suitable for insertion into a natural or artificial opening in a body, said tubular structure including an outer surface consisting of an acidic copolymer partially neutralized with sodium or potassium so that on intravascular insertion of said catheter the outer surface of said catheter becomes negatively charged as the result of release of positive Na or K ions into the environment, said negatively charged surface being non-thrombogenic.
Claim 5
Dependent Claim
19 words
A catheter as defined in claim 1, wherein said polymeric material is a copolymer of ethylene and acrylic acid.
Claim 6
Dependent Claim
29 words
A catheter as defined in claim 2, wherein said polymeric material has an acrylic acid content of about 10 to about 20% by weight, the remainder being copolymerized ethylene.
Claim 7
Dependent Claim
34 words
A catheter as defined in claim 3, wherein about 60% of the acid groups in said polymeric material are neutralized with a metallic ion chosen from the group consisting of Na and K .
Claim 8
Dependent Claim
55 words
A catheter as defined in claim 1, wherein said catheter further comprises an unstretched inner tube and an outer tube in the form of a coating on said inner tube, said coating being an acidic copolymer which is partly neutralized with one or more ions selected from the group consisting of Na and K .
Claim 9
Dependent Claim
33 words
A catheter as defined in claim 5, where said outer tube contains from about 10 to 20% by weight of acrylic acid copolymerized with ethylene, and neutralized to the extent of about 60%.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-06-02 | 1978-12-02 | 1979-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-06-02 | 1982-12-02 | 1983-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-06-02 | 1986-12-02 | 1987-06-03 | $7700.00 | Window Closed / Lapsed |