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US3867366A
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Opiate imidates and protein conjugates thereof
Assignee: SYNVAR ASSOCIATES A K A SYVA C
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Filing: 1973-05-09
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Granted: 1975-02-18
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Expires: 1993-05-09
Abstract
Abstract Novel water soluble opiate poly(amino acid) conjugates are provided, wherein the opiate is bound to the poly(amino acid) by an imidoyl linkage. The conjugates find use in the formation of antibodies or as reagents in immunoassays.
Inventors
- 👤 Kenneth E Rubenstein
- 👤 Edwin F Ullman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:52
CPC Classifications
C; C07; C07D; C07D489/00; C07D489/02; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/94; G01N33/946; G01N33/948; G01N33/9486; Y; Y10; Y10S; Y10S435/00; Y10S435/961; Y10S436/00; Y10S436/805; Y10S436/815; Y10S436/816; Y10S436/823; Y10S530/00; Y10S530/806
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
5 words
A CONJUGATE OF THE FORMULA:
Claim 2
Dependent Claim
5 words
A CONJUGATE OF THE FORMULA:
Claim 3
Dependent Claim
28 words
A conjugate according to claim 1, wherein Y is hydrogen, R is alkylene of from 1-4 carbon atoms, and n is in the range of 10 to 200.
Claim 4
Dependent Claim
12 words
An antibody prepared in response to a conjugate according to claim 2.
Claim 5
Dependent Claim
12 words
An antibody prepared in response to a conjugate according to claim 1.
Claim 6
Dependent Claim
16 words
A conjugate of bovine serum albumin and 2-(O3-morphinyl)acetimidoyl, wherein the linkage is through an amidine group.
Claim 7
Dependent Claim
16 words
A conjugate of bovine serum albumin and 2-(O3-morphinyl)acetimidoyl, wherein the linkage is through an amidine group.
References Cited (Backward Citations)
US3690834A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-02-17 | 1978-08-19 | 1979-02-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-02-17 | 1982-08-19 | 1983-02-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-02-17 | 1986-08-19 | 1987-02-18 | $7700.00 | Window Closed / Lapsed |