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US3864492A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treating depression using 1,4{40 -dihydroxy-3-n-pentyl-6,6,9-trimethyl-6a,7,10,10a-tetra-hydrodibenzo{8 b,d{9 pyran

Assignee: Abbott Laboratories
•
Filing: 1974-03-21
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Granted: 1975-02-04
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Expires: 1994-03-21
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Abstract

Abstract The compound 1,4''-dihydroxy-3-n-pentyl-6,6,9-trimethyl-6a, 7,10,10a-tetrahydrodibenzo(b,d)pyran, which can be prepared by microbial transformation of 1-hydroxy-3-n-pentyl-6,6,9-trimethyl6a,7,10,10a-tetrahydrobidenzo (b,d)pyran. The compound is useful as an antidepressant agent.

Inventors

  • 👤 Earl Elmer Fager
  • 👤 Norman Earl Wideburg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 05:35
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/35

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 25 words
A METHOD OF TREATING THE SYMPTOMS OF DEPRESSION COMPRISING ADMINISTERING A THERAPEUTICALLY EFFECTIVE AMOUNT OF 1,4''-DIHYDROXY-3-N-PENTYL-6,6,9-TRIMETHYL -6A,7,10,10ATETRAHYDRODIBENZO(B,D)PYRAN TO A PATIENT IN NEED OF SUCH TREATMENT.
Claim 2
Independent Claim 25 words
A METHOD OF TREATING THE SYMPTOMS OF DEPRESSION COMPRISING ADMINISTERING A THERAPEUTICALLY EFFECTIVE AMOUNT OF 1,4''-DIHYDROXY-3-N-PENTYL-6,6,9-TRIMETHYL -6A,7,10,10ATETRAHYDRODIBENZO(B,D)PYRAN TO A PATIENT IN NEED OF SUCH TREATMENT.
Claim 3
Dependent Claim 25 words
A method in accordance with claim 1 wherein a compound is administered in a dosage of from 0.5 to 100 mg./kg. of body weight daily.
Claim 4
Dependent Claim 28 words
A pharmaceutical composition in unit dosage form for treatment of symptoms of depression, comprising a therapeutically effective amount of 1,4''-dihydroxy-3-n-pentyl-6,6,9-trimethyl-6a, 7,10,10a-tetrahydrodibenzo(b,d)pyran and a pharmaceutically acceptable carrier or diluent.
Claim 5
Dependent Claim 28 words
A pharmaceutical composition in unit dosage form for treatment of symptoms of depression, comprising a therapeutically effective amount of 1,4''-dihydroxy-3-n-pentyl-6,6,9-trimethyl-6a, 7,10,10a-tetrahydrodibenzo(b,d)pyran and a pharmaceutically acceptable carrier or diluent.

References Cited (Backward Citations)

US3388136A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-02-03 1978-08-05 1979-02-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-02-03 1982-08-05 1983-02-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-02-03 1986-08-05 1987-02-04 $7700.00 Window Closed / Lapsed

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