US3853471A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Diagnostic composition for the detection of peroxidatively active substances in body fluids
Assignee: Roche Diagnostics GmbH
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Filing: 1973-07-03
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Granted: 1974-12-10
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Expires: 1993-07-03
Abstract
Abstract Test strips are provided for detecting even small amounts of blood or other peroxidatively active substances in body fluids; the strips comprising a carrier containing a hydroperoxide, at least one chromogen and, as a stabilizer, at least one phosphoric or phosphonic acid amide of the formula WHEREIN R1 is a dimethylamino, alkoxy, aryloxy, alkyl, aryl or Nmorpholine radical; and R2 and R3, which may be the same or different, are dimethylamino or N-morpholine radicals.
Inventors
- 👤 W Rittersdorf
- 👤 H Rey
- 👤 P Rieckmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:24
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; Y; Y10; Y10S; Y10S436/00; Y10S436/904
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
37 words
TEST STRIP FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES IN BODY FLUIDS, COMPRISING A CARRIER CONTAINING A HYDROPEROXIDE, AT LEAST ONE CHROMOGEN AND, AS A STABILIZER, AT LEAST ONE PHOSPHORIC OR PHOSPHONIC ACID AMIDE OF THE FORMULA
Claim 2
Dependent Claim
37 words
TEST STRIP FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES IN BODY FLUIDS, COMPRISING A CARRIER CONTAINING A HYDROPEROXIDE, AT LEAST ONE CHROMOGEN AND, AS A STABILIZER, AT LEAST ONE PHOSPHORIC OR PHOSPHONIC ACID AMIDE OF THE FORMULA
Claim 3
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R1 in the formula is dimethylamino.
Claim 4
Dependent Claim
15 words
Test strip as claimed in claim 1, wherein R1 in the formula is lower alkoxy.
Claim 5
Dependent Claim
20 words
Test strip as claimed in claim 1, wherein R1 in the formula is aryloxy of up to 10 carbon atoms.
Claim 6
Dependent Claim
15 words
Test strip as claimed in claim 1, wherein R1 in the formula is lower alkyl.
Claim 7
Dependent Claim
20 words
Test strip as claimed in claim 1, wherein R1 in the formula is aryl of up to 10 carboN atoms.
Claim 8
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R1 in the formula is N-morpholino.
Claim 9
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R2 in the formula is dimethylamino.
Claim 10
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R2 in the formula is N-morpholino.
Claim 11
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R3 in the formula is dimethylamino.
Claim 12
Dependent Claim
14 words
Test strip as claimed in claim 1, wherein R3 in the formula is N-morpholino.
Claim 13
Dependent Claim
15 words
Test strip as claimed in claim 1, wherein said acid amide is phosphoric acid trimorpholide.
Claim 14
Dependent Claim
16 words
Test strip as claimed in claim 1, wherein said acid amide is phosphoric acid dimethylamide dimorpholide.
Claim 15
Dependent Claim
17 words
Test strip as claimed in claim 1, wherein said acid amide is phosphoric acid ethyl ester dimorpholide.
Claim 16
Dependent Claim
16 words
Test strip as claimed in claim 1, wherein said acid amide is ethane phosphonic acid dimorpholide.
Claim 17
Dependent Claim
18 words
Test strip as claimed in claim 1, wherein the carrier is an absorbent material impregnated with the reagents.
Claim 18
Dependent Claim
17 words
Test strip as claimed in claim 1, wherein the carrier is a water-stable film containing the reagents.
Claim 19
Dependent Claim
22 words
Test strip as claimed in claim 1, wherein there is at least one mole of said acid amide per mole of hydroperoxide.
Claim 20
Dependent Claim
17 words
Test strip as claimed in claim 1, wherein a buffer is additionally contained in the test strip.
Claim 21
Dependent Claim
26 words
Test strip as claimed in claim 19, wherein sufficient buffer is provided to give a pH of 4 to 7 to the test strip in use.
Claim 22
Dependent Claim
25 words
Test strip as claimed in claim 1, also containing at least one of a complex former, a thickening agent, an activator and a wetting agent.
Claim 23
Dependent Claim
27 words
Method of detecting a peroxidatively active substance in a body fluid, which method comprises contacting a test sample with a test strip as claimed in claim 1.
Claim 24
Dependent Claim
13 words
Method as claimed in claim 22, wherein said peroxidatively active substance is blood.
References Cited (Backward Citations)
US3252762A
Cited
US3290117A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-09 | 1978-06-10 | 1978-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-09 | 1982-06-10 | 1982-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-09 | 1986-06-10 | 1986-12-10 | $7700.00 | Window Closed / Lapsed |