Acetoxy methyl and pivaloyloxymethyl 5-acetamido-2,4,6-triiodo-n-methylisophthalamates
Abstract
Abstract IODINE-CONTAINING ORGANIC ACIDS OF THE FORMULA XYCH-COOR WHEREIN R IS AN ELECTRON-ATTRACTING GROUP AND EITHER X IS HYDROGEN AND Y IS A GROUP OF THE FORMULA: 3,5-DI(I-),2-(O=)PYRIDINO OR 1,3,5-TRI(I-),2-(CH3-NH-CO-),4-(CH3-CO-NH-)PHENYL OR X IS CH3-(CH3)N WHEREIN N IS 0 TO 6 AND Y IS A GROUP OF THE FORMULA: (TRI(I-)PHENYL)-Z- WHEREIN Z IS OXYGEN, SULPHUR OR (CH2)M WHEREIN M IS 0 TO 6 AND WHEN Z IS CH2 THERE MAY BE A NH2 GROUP IN THE 3-POSITION, ARE USEFUL AS X-RAY CONTRAST AGENTS. ACETOXYMETHYL 5-ACETAMIDO-2,4,6-TRIIODO-N-METHYLISOPHTHALAMATE, PIVALOYLOXYMETHYL 5-ACETAMIDO-2,4,6-TRIIODO-N-METHYLISOPHPHTHALAMATE, ACETOXYMETHYL 3-AMINO-A-ETHYL-2,4,6-TRIIODOHYDROCINNAMATE, AND PIVALOYLOXYMETHYL 3-AMINO-AETHYL-2,4,6-TRIIODOHYDROCINNAMATE ARE ALSO USEFUL AS XRAY CONTRAST AGENTS.
Inventors
- 👤 M Soulal
- 👤 K Utting
Bibliographic Details
Claims Analysis
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