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US3792276A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and apparatus for programming liquid scintillation spectrometers

Assignee: Revvity Health Sciences Inc
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Filing: 1971-10-12
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Granted: 1974-02-12
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Expires: 1991-10-12
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Abstract

Abstract In an automatic scintillation counting device adapted to detect and measure the radioactivity of a multiplicity of samples supplied in trays or other sets, provisions are made for automatically changing one or more of the analog counting parameters, or analog-plus-digital parameters, for each set. The changes are effected automatically as each sample set comes into counting position, thereby permitting unattended automatic counting of samples requiring entirely different counting parameters. At the analyst''s option, two or more sets may be counted under conditions established for one of the sets. Provisions are also made for retaining the operation of the master, or front panel, control when it is unnecessary to vary the counting program parameters for particular sets.

Inventors

  • 👤 J Toman
  • 👤 E Frank

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 13:59
CPC Classifications
G; G01; G01T; G01T7/00; G01T7/08; G01T1/00; G01T1/16; G01T1/20; G01T1/204

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 277 words
In a scintillation spectrometer for automatically and sequentially handling and counting a multiplicty of radioactive samples, including A. a sample counting zone, B. means for counting said samples individually in said counting zone, including 1. means responsive to radioactivity decay events for producing electrical pulses having an amplitude related to the energy of corresponding decay events, 2. an amplification-discrimination channel receiving said electrical pulses, said channel having a. an electronic amplifier for amplifying pulses from said event responsive means, and b. upper and lower level discriminators for passing only a selected amplitude band of amplified pulses therethrough, and 3. means for counting discriminated amplified signals as a measure of the number of said decay events, C. a first analog parameter control for controlling at least one of (i) the gain of said electronic amplifier, (ii) said upper level discriminator and (iii) said lower level discriminator, and D. means for transferring said multiplicity of samples in a plurality of sets to said sample counting zone for individual counting of samples, the improvement whereby at least one of the pulse amplifying amplifier parameters is programmed to effect counting of samples within each set at at least one predetermined analog parameter different from parameters for other sets, which comprises: E. a replaceable analog parameter control having predetermined control settings and associated with an individual one of said plurality of sets, F. means for determining the particular one of said sets then having its samples transferred to said sample counting zone, and G. means responsive to said set determining means for disconnecting said first analog parameter control out of, and for connecting said replaceable analog parameter control into, said amplifier-discriminator channel.
Claim 2
Dependent Claim 277 words
In a scintillation spectrometer for automatically and sequentially handling and counting a multiplicty of radioactive samples, including A. a sample counting zone, B. means for counting said samples individually in said counting zone, including 1. means responsive to radioactivity decay events for producing electrical pulses having an amplitude related to the energy of corresponding decay events, 2. an amplification-discrimination channel receiving said electrical pulses, said channel having a. an electronic amplifier for amplifying pulses from said event responsive means, and b. upper and lower level discriminators for passing only a selected amplitude band of amplified pulses therethrough, and 3. means for counting discriminated amplified signals as a measure of the number of said decay events, C. a first analog parameter control for controlling at least one of (i) the gain of said electronic amplifier, (ii) said upper level discriminator and (iii) said lower level discriminator, and D. means for transferring said multiplicity of samples in a plurality of sets to said sample counting zone for individual counting of samples, the improvement whereby at least one of the pulse amplifying amplifier parameters is programmed to effect counting of samples within each set at at least one predetermined analog parameter different from parameters for other sets, which comprises: E. a replaceable analog parameter control having predetermined control settings and associated with an individual one of said plurality of sets, F. means for determining the particular one of said sets then having its samples transferred to said sample counting zone, and G. means responsive to said set determining means for disconnecting said first analog parameter control out of, and for connecting said replaceable analog parameter control into, said amplifier-discriminator channel.
Claim 3
Dependent Claim 41 words
an amplification-discrimination channel receiving said electrical pulses, said channel having a. an electronic amplifier for amplifying pulses from said event responsive means, and b. upper and lower level discriminators for passing only a selected amplitude band of amplified pulses therethrough, and
Claim 4
Dependent Claim 41 words
an amplification-discrimination channel receiving said electrical pulses, said channel having a. an electronic amplifier for amplifying pulses from said event responsive means, and b. upper and lower level discriminators for passing only a selected amplitude band of amplified pulses therethrough, and
Claim 5
Dependent Claim 34 words
Spectrometer of claim 1 including a plurality of said amplification-discrimination channels, wherein said first analog parameter control and said replaceable analog parameter control control at least one analog parameter in each of said channels.
Claim 6
Dependent Claim 18 words
Spectrometer of claim 1 wherein said replaceable analog parameter control controls said gain and both of said discriminators.
Claim 7
Dependent Claim 178 words
means for counting discriminated amplified signals as a measure of the number of said decay events, C. a first analog parameter control for controlling at least one of (i) the gain of said electronic amplifier, (ii) said upper level discriminator and (iii) said lower level discriminator, and D. means for transferring said multiplicity of samples in a plurality of sets to said sample counting zone for individual counting of samples, the improvement whereby at least one of the pulse amplifying amplifier parameters is programmed to effect counting of samples within each set at at least one predetermined analog parameter different from parameters for other sets, which comprises: E. a replaceable analog parameter control having predetermined control settings and associated with an individual one of said plurality of sets, F. means for determining the particular one of said sets then having its samples transferred to said sample counting zone, and G. means responsive to said set determining means for disconnecting said first analog parameter control out of, and for connecting said replaceable analog parameter control into, said amplifier-discriminator channel.
Claim 8
Dependent Claim 178 words
means for counting discriminated amplified signals as a measure of the number of said decay events, C. a first analog parameter control for controlling at least one of (i) the gain of said electronic amplifier, (ii) said upper level discriminator and (iii) said lower level discriminator, and D. means for transferring said multiplicity of samples in a plurality of sets to said sample counting zone for individual counting of samples, the improvement whereby at least one of the pulse amplifying amplifier parameters is programmed to effect counting of samples within each set at at least one predetermined analog parameter different from parameters for other sets, which comprises: E. a replaceable analog parameter control having predetermined control settings and associated with an individual one of said plurality of sets, F. means for determining the particular one of said sets then having its samples transferred to said sample counting zone, and G. means responsive to said set determining means for disconnecting said first analog parameter control out of, and for connecting said replaceable analog parameter control into, said amplifier-discriminator channel.
Claim 9
Dependent Claim 18 words
Spectrometer of claim 1 wherein said replaceable analog parameter control controls both said discriminators but not said gain.
Claim 10
Dependent Claim 24 words
Spectrometer of claim 1 wherein said replaceable analog parameter control additionally controls gain at 100 percent of gain and at 10 percent of gain.
Claim 11
Dependent Claim 34 words
Spectrometer of claim 1 including at least one additional replaceable analog parameter control associated with one of said sets and adapted to select the replaceable analog parameter control associated with another of said sets.
Claim 12
Dependent Claim 25 words
Spectrometer of claim 1 including manual switch means on said replaceable analog parameter control for retaining analog parameter controls by said first analog parameter control.
Claim 13
Dependent Claim 18 words
Spectrometer of claim 1 including a separate replaceable analog parameter control associated with each one of said sets.
Claim 14
Dependent Claim 75 words
Spectrometer of claim 1 including a first digital parameter control for controlling at least one digital parameter of said sample counting means, a replaceable digital parameter control having predetermined control settings and associated with said replaceable analog parameter control, and means responsive to said connecting or disconnecting of said replaceable analog parameter control for disconnecting said first digital parameter control out of, and for connecting said replaceable digital parameter control into, said sample counting means.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-02-11 1977-08-13 1978-02-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-02-11 1981-08-13 1982-02-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-02-11 1985-08-13 1986-02-12 $7700.00 Window Closed / Lapsed

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