Abstract An intratracheal sampling device comprising an inner collection tube coextensively and retractably mounted within a hollow probe for insertion within the larynx of a subject animal with the collection tube in a retracted position. Depression of a plunger mounted at the external end of the probe extends the collection tube within the animal''s trachea and at the same time activates means for supplying wash fluid to the probe as well as vacuum means communicating, via a sample collection vessel, with the collection tube. Wash fluid is ejected in a jetting action through an annular clearance between the distal end of the probe and the extended collection tube. The ejected fluid, together with contained exfoliated cells from the tracheal walls, is recovered in the sample collection vessel after returning through the collection tube.
Inventors
👤 H Schreiber
Bibliographic Details
Application Number—
JurisdictionUS
Data Sourcegoogle_patents
Last Synchronized2026-10-22 22:30
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/02
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
175 words
Apparatus for collecting cells from animal respiratory tracts comprising: a. an elongated hollow probe having a handle portion and a tapered extension portion for insertion into the respiratory tract to be sampled, said extension portion terminating in a wash liquid discharge end; b. a flexible sample collection tube having first and second ends, said sample collection tube being slidably mounted within said probe and selectively extensible from said wash liquid discharge end thereof; c. means for selectively extending said first end of said sample collection tube from said wash liquid discharge end; d. means for ejecting wash liquid from said wash liquid discharge end of said probe; e. means, in fluid communication with said second end of said collection tube, for maintaining reduced pressure in said tube so as to cause ejected wash liquid and exfoliated cels contained therein to enter said first end of saiD tube and flow therethrough; and f. a collection chamber in fluid communication with said second end of said collection tube for receiving sample material removed through said collection tube.
Claim 2
Dependent Claim
175 words
Apparatus for collecting cells from animal respiratory tracts comprising: a. an elongated hollow probe having a handle portion and a tapered extension portion for insertion into the respiratory tract to be sampled, said extension portion terminating in a wash liquid discharge end; b. a flexible sample collection tube having first and second ends, said sample collection tube being slidably mounted within said probe and selectively extensible from said wash liquid discharge end thereof; c. means for selectively extending said first end of said sample collection tube from said wash liquid discharge end; d. means for ejecting wash liquid from said wash liquid discharge end of said probe; e. means, in fluid communication with said second end of said collection tube, for maintaining reduced pressure in said tube so as to cause ejected wash liquid and exfoliated cels contained therein to enter said first end of saiD tube and flow therethrough; and f. a collection chamber in fluid communication with said second end of said collection tube for receiving sample material removed through said collection tube.
Claim 3
Dependent Claim
58 words
The apparatus of claim 1 wherein said wash liquid discharge end of said probe comprises a polytetrafluorethylene sleeve having an internal diameter which is greater than the external diameter of said sample collection tube, said sample collection tube extending coaxially through said sleeve, wash liquid being ejected through the annular clearance between said sleeve and said collection tube.
Claim 4
Dependent Claim
42 words
The apparatus of claim 1 wherein said means for selectively extending said first end of said sample collection tube from said wash liquid discharge end comprises a plunger fixed to said tube and slidably disposed within said handle portion of said probe.
Claim 5
Dependent Claim
33 words
The apparatus of claim 3 wherein said plunger activates said means for ejecting wash liquid from said wash liquid discharge end and said means for maintaining reduced pressure in said sample collection tube.
Claim 6
Dependent Claim
36 words
The apparatus of claim 4 further including a timer for shutting off said means for ejecting wash liquid from said wash liquid discharge end and said means for maintaining reduced pressure in said sample collection tube.