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US3788305A Expired / Lapsed US ⏱️ 0.0 years remaining

Intratracheal sampling device

Assignee: United States Atomic Energy Commission
•
Filing: 1972-10-19
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Granted: 1974-01-29
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Expires: 1992-10-19
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Abstract

Abstract An intratracheal sampling device comprising an inner collection tube coextensively and retractably mounted within a hollow probe for insertion within the larynx of a subject animal with the collection tube in a retracted position. Depression of a plunger mounted at the external end of the probe extends the collection tube within the animal''s trachea and at the same time activates means for supplying wash fluid to the probe as well as vacuum means communicating, via a sample collection vessel, with the collection tube. Wash fluid is ejected in a jetting action through an annular clearance between the distal end of the probe and the extended collection tube. The ejected fluid, together with contained exfoliated cells from the tracheal walls, is recovered in the sample collection vessel after returning through the collection tube.

Inventors

  • 👤 H Schreiber

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 22:30
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/02

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 175 words
Apparatus for collecting cells from animal respiratory tracts comprising: a. an elongated hollow probe having a handle portion and a tapered extension portion for insertion into the respiratory tract to be sampled, said extension portion terminating in a wash liquid discharge end; b. a flexible sample collection tube having first and second ends, said sample collection tube being slidably mounted within said probe and selectively extensible from said wash liquid discharge end thereof; c. means for selectively extending said first end of said sample collection tube from said wash liquid discharge end; d. means for ejecting wash liquid from said wash liquid discharge end of said probe; e. means, in fluid communication with said second end of said collection tube, for maintaining reduced pressure in said tube so as to cause ejected wash liquid and exfoliated cels contained therein to enter said first end of saiD tube and flow therethrough; and f. a collection chamber in fluid communication with said second end of said collection tube for receiving sample material removed through said collection tube.
Claim 2
Dependent Claim 175 words
Apparatus for collecting cells from animal respiratory tracts comprising: a. an elongated hollow probe having a handle portion and a tapered extension portion for insertion into the respiratory tract to be sampled, said extension portion terminating in a wash liquid discharge end; b. a flexible sample collection tube having first and second ends, said sample collection tube being slidably mounted within said probe and selectively extensible from said wash liquid discharge end thereof; c. means for selectively extending said first end of said sample collection tube from said wash liquid discharge end; d. means for ejecting wash liquid from said wash liquid discharge end of said probe; e. means, in fluid communication with said second end of said collection tube, for maintaining reduced pressure in said tube so as to cause ejected wash liquid and exfoliated cels contained therein to enter said first end of saiD tube and flow therethrough; and f. a collection chamber in fluid communication with said second end of said collection tube for receiving sample material removed through said collection tube.
Claim 3
Dependent Claim 58 words
The apparatus of claim 1 wherein said wash liquid discharge end of said probe comprises a polytetrafluorethylene sleeve having an internal diameter which is greater than the external diameter of said sample collection tube, said sample collection tube extending coaxially through said sleeve, wash liquid being ejected through the annular clearance between said sleeve and said collection tube.
Claim 4
Dependent Claim 42 words
The apparatus of claim 1 wherein said means for selectively extending said first end of said sample collection tube from said wash liquid discharge end comprises a plunger fixed to said tube and slidably disposed within said handle portion of said probe.
Claim 5
Dependent Claim 33 words
The apparatus of claim 3 wherein said plunger activates said means for ejecting wash liquid from said wash liquid discharge end and said means for maintaining reduced pressure in said sample collection tube.
Claim 6
Dependent Claim 36 words
The apparatus of claim 4 further including a timer for shutting off said means for ejecting wash liquid from said wash liquid discharge end and said means for maintaining reduced pressure in said sample collection tube.

References Cited (Backward Citations)

US989839A Cited
US3096764A Cited
US3429313A Cited
US3426759A Cited
US3635220A Cited
US3626928A Cited
US3735751A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-01-28 1977-07-30 1978-01-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-01-28 1981-07-30 1982-01-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-01-28 1985-07-30 1986-01-29 $7700.00 Window Closed / Lapsed

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