Method for the manufacture of effervescent tablets
Abstract
Abstract METHOD FOR THE MANUFACTURE OF EFFERVESCENT TABLETS CONTAINING ON THE ONE HAND AT LEAST ONE MEDICINE, ON THE OTHER HAND AN EFFERVESCENT MIXTURE COMPRISING THE GRANULATION OF THE EFFERVESCENT MIXTURE POSSIBLY CONTAINING THE MEDICINE IN THREE STAGES: (1) THE HUMIDIFICATION OF THE EFFERVESCENT MIXTURE BY MEANS OF A QUANTITY OF WATER LESS THAN 1% BY WEIGHT WITH RESPECT TO THE ALKALINE BICARBONATE; (2) THE PRE-DRYING OF THE HUMIDIFIED EFFERVESCENT MIXTURE IN A FLUIDIZED BED, BY HOT AIR, THE MOISTURE CONTENT OF WHICH DOES NOT EXCEED 5 G./M.3 AND THE TEMPERATURE OF WHICH DOES NOT EXCEED 60*C., THIS OPERATION TAKING PLACE BY A SEQUENCE OF SHORT DRYING OPERATIONS SO AS TO STOP THE CHEMICAL REACTION; AND (3) THE FINAL DRYING OF THE GRANULATED MIXTURE BY HOT AIR, THE MOISTURE CONTENT OF WHICH DOES NOT EXCEED 5 G./M.3 AND THE TEMPERATURE OF WHICH DOES NOT EXCEED 60*C., IN A FLUIDIZED BED, UNTIL THE RESIDUAL CONTENT OF WATER IN THE GRANULES IS LESS THAN 0.25% BY WEIGHT AND, PREFERABLY COMPRISED BETWEEN 0.05 AND 0.15%.
Inventors
- 👤 G Gergely
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-11-19 | 1977-05-21 | 1977-11-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-11-19 | 1981-05-21 | 1981-11-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-11-19 | 1985-05-21 | 1985-11-20 | $7700.00 | Window Closed / Lapsed |