Abstract The disclosure is directed to an improvement in a universal dispensing package for medicaments to be dissolved in a parenteral container prior to use. The package is made up of a container and a cap which has a hollow piercing device for dispensing medicament from the container into a closed system parenteral solution bottle, and second has a frusto-conical shank adapted to engage the interior surface of the neck of an open system parenteral solution container. A hydrophobic membrane filter is provided as a vent in the cap to relive the vacuum to allow for dispensing of the medicament. The present improvement comprises spacers, or studs, formed at the base of the piercing device to space the hydrophobic vent at a predetermined distance from the parenteral container when used in conjunction with a closed system parenteral solution bottle.
A medicament-dispensing package for use with a parenteral solution container comprising: A. A variable volume reservoir adapted to contain a medicament; ii. A plurality of spaced sealing members defined on the distal end of said reservoir and adapted to engage the interior surfaces of an open system parenteral solution container; B. A single fitment connected to said reservoir and further comprising a conduit adapted to convey said medicament from said reservoir to the parenteral solution container; i. Said conduit being located on the proximal end of said fitment and located offcenter of said fitment; ii. An orifice defined in the proximal end of said fitment and adapted to receive a vent filter; C. Means connected to said fitment and adapted to sealably engage a closed system parenteral solution container; D. A vent filter mounted in said orifice in the proximal end of said fitmEnt and adapted to equalize pressure within and without said reservoir; i. Said vent filter being located offcenter of said fitment opposite said offcenter conduit; E. At least one spacer connected to said fitment and extending axially away from said fitment adjacent to said offcenter conduit, said spacer being higher than the vertical height of the vent filter mounting and adapted to space said vent filter a predetermined distance from a closed parenteral solution bottle; and F. Means to retain the medicament in said reservoir.
Claim 2
Dependent Claim
228 words
A medicament-dispensing package for use with a parenteral solution container comprising: A. A variable volume reservoir adapted to contain a medicament; ii. A plurality of spaced sealing members defined on the distal end of said reservoir and adapted to engage the interior surfaces of an open system parenteral solution container; B. A single fitment connected to said reservoir and further comprising a conduit adapted to convey said medicament from said reservoir to the parenteral solution container; i. Said conduit being located on the proximal end of said fitment and located offcenter of said fitment; ii. An orifice defined in the proximal end of said fitment and adapted to receive a vent filter; C. Means connected to said fitment and adapted to sealably engage a closed system parenteral solution container; D. A vent filter mounted in said orifice in the proximal end of said fitmEnt and adapted to equalize pressure within and without said reservoir; i. Said vent filter being located offcenter of said fitment opposite said offcenter conduit; E. At least one spacer connected to said fitment and extending axially away from said fitment adjacent to said offcenter conduit, said spacer being higher than the vertical height of the vent filter mounting and adapted to space said vent filter a predetermined distance from a closed parenteral solution bottle; and F. Means to retain the medicament in said reservoir.
Claim 3
Dependent Claim
17 words
A package as defined in claim 1 wherein said vent filter is comprised of a hydrophobic membrane.
Claim 4
Dependent Claim
20 words
The package as defined in claim 1 in which said spacer provides a predetermined distance of at least one-sixteenth inches.
Claim 5
Dependent Claim
17 words
The package as defined in claim 2 wherein said medicament retaining means is a hydrophobic membrane filter.
Claim 6
Dependent Claim
22 words
The package as defined in claim 2 wherein said vent filter has a mean pore size of about 0.2 to 1.2 microns.
Claim 7
Dependent Claim
22 words
The package as defined in claim 4 wherein the pore size of said retaining membrane filter is about 3 to 10 microns.