US3723244A
Expired / Lapsed
US
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Fibrous fibrin sheet and method for producing same
Assignee: United States Atomic Energy Commission
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Filing: 1971-01-18
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Granted: 1973-03-27
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Expires: 1991-01-18
Abstract
Abstract Fibrin in sheet form is prepared by centrifuging an aqueous dispersion of monomeric fibrin under fibrin-polymerizing conditions. The centrifugation is conducted in a vessel having a wall for intercepting centrifuged particles and at a speed pelletizing the resulting strands of polymerized fibrin thereon. The pelletized strands interlock to form a fibrous sheet, which is removed from the vessel.
Inventors
- 👤 J Breillatt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:49
CPC Classifications
D; D21; D21H; D21H13/00; D21H13/10; D21H13/28; D21H13/34; A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/225; D21H5/00; D21H5/12; D21H5/1209; A61F; A61F2310/00; A61F2310/00005; A61F2310/00365; A61F2310/00377; Y; Y10; Y10S; Y10S602/00; Y10S602/90
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
13 words
The method of claim 1 wherein said aqueous dispersion comprises whole blood plasma.
Claim 2
Dependent Claim
13 words
The method of claim 1 wherein said aqueous dispersion comprises a blood plasma.
Claim 3
Dependent Claim
39 words
The method of claim 1 wherein said aqueous dispersion is provided in the form of an aqueous solution of purified fibrinogen, a divalent alkaline earth cation, and a small but effective amount of a catalyst for the fibrinogen-to-monomeric-fibrin reaction.
Claim 4
Dependent Claim
20 words
The method of claim 1 wherein said aqueous dispersion is at a pH in the range of 5.5 to 10.5.
Claim 5
Dependent Claim
22 words
The method of claim 1 wherein said centrifuging step is conducted at a temperature in the range of 15* to 55* C.
Claim 6
Dependent Claim
23 words
The method of claim 1 wherein said centrifuging step is conducted at a speed generating a pelletizing force of at least 20,000 g.
Claim 7
Dependent Claim
11 words
A sheet of fibrin produced by the process of claim 1.
References Cited (Backward Citations)
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US2533004A
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US2992882A
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US3036341A
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US3014024A
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US3210241A
Cited
US3523807A
Cited
US3617443A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-03-26 | 1976-09-25 | 1977-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-03-26 | 1980-09-25 | 1981-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-03-26 | 1984-09-25 | 1985-03-27 | $7700.00 | Window Closed / Lapsed |