US3698560A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hollow fiber, artificial kidney with disposable dialyzing cartridge
Assignee: United States Department of Health and Human Services
•
Filing: 1970-12-28
•
Granted: 1972-10-17
•
Expires: 1990-12-28
Abstract
Abstract A hollow-fiber, artificial kidney with a disposable dialyzing cartridge comprising a cylindrical body, a disposable dialyzing cartridge positioned during use within the body and having hollow dialyzing fibers therein, and flanges and other means to hold the assembled parts of the kidney in place.
Inventors
- 👤 James S Tapp
- 👤 George L Beemsterboer
- 👤 Ival O Salyer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:56
CPC Classifications
B; B01; B01D; B01D63/00; B01D63/02; B01D63/034; B01D65/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
182 words
A hollow-fiber, artificial kidney with a disposable dialyzing cartridge comprising a first elongated hollow body open at both ends, having inlet and outlet ports near opposite ends of said body, and a gasket located in the inner wall of said body between the inlet and outlet ports to prevent dialyzing fluid from going directly from inlet to outlet; a disposable dialyzing cartridge comprising a second elongated hollow body, sized to be inserted and removed from inside said first body, having one or more openings on the side near each end positioned to communicate with inlet and outlet ports of said first body, and hollow dialyzing fibers running longitudinally inside said second body and potted with resin into a reduced internal opening at each end to prevent leakage of dialyzing fluid around the fibers and out of either end; a gasket at each end of said first and second bodies to prevent dialyzing fluid from leaking into blood, a flange at each end of said bodies, and means joining said flanges to hold said bodies and the gasket at each end in place.
Claim 2
Dependent Claim
182 words
A hollow-fiber, artificial kidney with a disposable dialyzing cartridge comprising a first elongated hollow body open at both ends, having inlet and outlet ports near opposite ends of said body, and a gasket located in the inner wall of said body between the inlet and outlet ports to prevent dialyzing fluid from going directly from inlet to outlet; a disposable dialyzing cartridge comprising a second elongated hollow body, sized to be inserted and removed from inside said first body, having one or more openings on the side near each end positioned to communicate with inlet and outlet ports of said first body, and hollow dialyzing fibers running longitudinally inside said second body and potted with resin into a reduced internal opening at each end to prevent leakage of dialyzing fluid around the fibers and out of either end; a gasket at each end of said first and second bodies to prevent dialyzing fluid from leaking into blood, a flange at each end of said bodies, and means joining said flanges to hold said bodies and the gasket at each end in place.
Claim 3
Dependent Claim
21 words
An artificial kidney of claim 1 having a necked-down longitudinal portion adjacent each end to facilitate connecting said kidney for use.
Claim 4
Dependent Claim
97 words
An artificial kidney of claim 1 wherein the hollow-fibers are quaternized heparinized hollow-fibers of a polymer made from monomeric substances of which at least a sufficient amount of a vinylpyridine is included to provide membranes which on heparinization are non-thrombo-genic and at least 50 percent is acrylonitrile, said hollow-fiber having a urea permeability in the range of 0.005 to 0.075 cm./min. and an ultrafiltration rate in the range of 3 to 300 ml./min./m.2 at 25 mm.Hg. transmembrane pressure, and all portions of said kidney which are in contact with blood are heparinized to prevent clotting of blood.
Claim 5
Independent Claim
152 words
A method for potting hollow dialyzing fiBers into an elongated hollow body comprising positioning said body having a reduced opening at each end and hollow dialyzing fibers running longitudinally through said body and out each end, in an upright hollow body closed at the bottom and having glycerine therein, adjusting the level of said elongated body and fibers in the glycerine until the dialyzing area of the fibers is covered by glycerine but the upper end of said elongated body with protruding fibers extends above the glycerine, adding a potting resin of lower density than glycerine around the fibers inside the upper end of said elongated body taking care to displace air bubbles to facilitate obtaining a non-leaking seal of the fibers to each other and to the elongated body, curing said resin to obtain the seal, and repeating the potting operation described hereinabove at the other end of said elongated body.
Claim 6
Independent Claim
152 words
A method for potting hollow dialyzing fiBers into an elongated hollow body comprising positioning said body having a reduced opening at each end and hollow dialyzing fibers running longitudinally through said body and out each end, in an upright hollow body closed at the bottom and having glycerine therein, adjusting the level of said elongated body and fibers in the glycerine until the dialyzing area of the fibers is covered by glycerine but the upper end of said elongated body with protruding fibers extends above the glycerine, adding a potting resin of lower density than glycerine around the fibers inside the upper end of said elongated body taking care to displace air bubbles to facilitate obtaining a non-leaking seal of the fibers to each other and to the elongated body, curing said resin to obtain the seal, and repeating the potting operation described hereinabove at the other end of said elongated body.
Claim 7
Dependent Claim
91 words
A disposable dialyzing cartridge usable in a hollow-fiber, artificial kidney comprising of an elongated hollow body beveled at both ends and adapted to be inserted and removed from said artificial kidney, having one or more openings on the side at each end positioned to communicate with inlet and outlet dialyzing fluid ports of an artificial kidney, and hollow dialyzing fibers running longitudinally inside said body and potted with resin into a reduced internal opening near each end to prevent leakage of dialyzing fluid around the fibers and out of either end.
Claim 8
Dependent Claim
91 words
A disposable dialyzing cartridge usable in a hollow-fiber, artificial kidney comprising of an elongated hollow body beveled at both ends and adapted to be inserted and removed from said artificial kidney, having one or more openings on the side at each end positioned to communicate with inlet and outlet dialyzing fluid ports of an artificial kidney, and hollow dialyzing fibers running longitudinally inside said body and potted with resin into a reduced internal opening near each end to prevent leakage of dialyzing fluid around the fibers and out of either end.
Claim 9
Dependent Claim
81 words
The disposable dialyzing cartridge of claim 5 wherein said hollow dialyzing fibers are quaternized heparinized hollow-fibers of a polymer made from monomeric substances of which at least a sufficient amount of a vinylpyridine is included to provide membranes which on heparinization are non-thrombogenic and at least 50 percent acrylonitrile, said hollow-fiber having a urea permeability in the range of 0.005 to 0.075 cm/min. and an ultrafiltration rate in the range of 3 to 300 ml/min./m2 at 25 mm. Hg. transmembrane pressure.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-10-17 | 1976-04-17 | 1976-10-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-10-17 | 1980-04-17 | 1980-10-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-10-17 | 1984-04-17 | 1984-10-17 | $7700.00 | Window Closed / Lapsed |