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US3625745A Expired / Lapsed US ⏱️ 0.0 years remaining

Antithrombogenic article and process

Assignee: General Electric Co
•
Filing: 1970-03-18
•
Granted: 1971-12-07
•
Expires: 1990-03-18
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Abstract

Abstract A thin, continuous adherent coating is formed on a substrate by ultraviolet surface photopolymerization of a synthetic organic antithrombogenic compound in the gaseous phase. The resulting coated article exhibits antithrombogenic behavior and is suitable for prosthetic use.

Inventors

  • 👤 Archibald N Wright
  • 👤 Hans-Dieter Becker

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 23:56
CPC Classifications
B; B05; B05D; B05D1/00; B05D1/60; A; A61; A61L; A61L33/00; A61L33/0005; B05D3/00; B05D3/06; B05D3/061; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/3154; Y10T428/31678

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 26 words
A process according to claim 1 wherein said synthetic organic antithrombogenic compound is selected from the group consisting of an anticoagulant compound and a fibrinolytic compound.
Claim 2
Dependent Claim 15 words
A process according to claim 1 wherein said synthetic organic antithrombogenic compound is vinyl substituted.
Claim 3
Dependent Claim 27 words
A process according to claim 2 wherein said anticoagulant compound is selected from the group consisting of bishydroxycoumarin, ethyl biscoumacetate, 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin, 2-phenylindane-1,3-dione, 2(p-(phenylsulfonyl) phenyl)-1,3-indanedione, and 2-diphenylacetyl-1, 3-indanedione.
Claim 4
Dependent Claim 31 words
A process according to claim 2 wherein said fibrinolytic compound is sElected from the group consisting of epsilon -aminocaproic acid, p-aminobenzoic acid, salicylic acid, aspirin, phenylbutazone, urethane, dextran, chlorpheniramine, and dipyridamole.
Claim 5
Dependent Claim 12 words
A process according to claim 1 wherein said substrate is a metal.
Claim 6
Dependent Claim 12 words
A process according to claim 1 wherein said substrate is a nonmetal.
Claim 7
Dependent Claim 57 words
An antithrombogenic article comprised of a substrate the surface of which is coated with an adherent continuous thin coating of a surface photopolymerized vapor of a synthetic organic antithrombogenic compound, said synthetic organic antithrombogenic compound being vaporizable in a substantial vacuum by heat without being significantly degraded to produce a vapor pressure of less than 10 torr.
Claim 8
Dependent Claim 27 words
An antithrombogenic article according to claim 8 wherein said synthetic organic antithrombogenic compound is selected from the group consisting of an anticoagulant compound and a fibrinolytic compound.
Claim 9
Dependent Claim 28 words
An antithrombogenic article according to claim 9 wherein said anticoagulant compound is selected from the group consisting of bishydroxycoumarin, ethyl biscoumacetate, 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin, 2-phenylindane- 1,3-dione, 2(p-(phenylsulfonyl) phenyl)-1,3-indanedione, and 2-diphenylacetyl-1,3-indanedione.
Claim 10
Dependent Claim 32 words
An antithrombogenic article according to claim 9 wherein said fibrinolytic compound is selected from the group consisting of epsilon -aminocaproic acid, p-aminobenzoic acid, salicylic acid, aspirin, phenylbutazone, urethane, dextran, chlorpheniramine, and dipyridamole.
Claim 11
Dependent Claim 13 words
An antithrombogenic article according to claim 8 wherein said substrate is a metal.
Claim 12
Dependent Claim 13 words
An antithrombogenic article according to claim 8 wherein said substrate is a nonmetal.

References Cited (Backward Citations)

US3508959A Cited
US3453194A Cited
US3511684A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-12-06 1975-06-07 1975-12-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-12-06 1979-06-07 1979-12-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-12-06 1983-06-07 1983-12-07 $7700.00 Window Closed / Lapsed

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