US3598123A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bandage for administering drugs
Assignee: Alza Corp
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Filing: 1969-04-01
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Granted: 1971-08-10
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Expires: 1989-04-01
Abstract
Abstract Bandage for use in the continuous administration of drugs by absorption comprising a backing member bearing a pressuresensitive adhesive layer on one surface thereof. Distributed throughout the pressure-sensitive adhesive are microcapsules comprised of a systemically active drug encapsulated with a material permeable to passage of the drug. The drug is in a form acceptable for absorption through the skin or the mucosa of the mouth.
Inventors
- 👤 Alejandro Zaffaroni
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 16:29
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K9/7061; A61K9/7069; A61K9/7092; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
115 words
A medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active drugs over a prolonged period of time by absorption through the external body skin or mucosa, said bandage comprising (1) a backing member bearing (2) a pressure-sensitive adhesive on one surface thereof, said pressure-sensitive adhesive having distributed therethrough (3) a plurality of discrete microcapsules, each of which microcapsules comprising a systemically active drug formulation confined within a wall member, said wall member being formed from drug release rate controlling material to continuously meter the flow of drUg from the said microcapsules to the skin or mucosa at a controlled and predetermined rate over a prolonged period of time.
Claim 2
Dependent Claim
115 words
A medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active drugs over a prolonged period of time by absorption through the external body skin or mucosa, said bandage comprising (1) a backing member bearing (2) a pressure-sensitive adhesive on one surface thereof, said pressure-sensitive adhesive having distributed therethrough (3) a plurality of discrete microcapsules, each of which microcapsules comprising a systemically active drug formulation confined within a wall member, said wall member being formed from drug release rate controlling material to continuously meter the flow of drUg from the said microcapsules to the skin or mucosa at a controlled and predetermined rate over a prolonged period of time.
Claim 3
Dependent Claim
30 words
The bandage as defined by claim 1, wherein each of said microcapsules (3) is comprised of systemically active drug formulation microencapsulated with the said drug release rate controlling wall material.
Claim 4
Dependent Claim
36 words
The bandage as defined by claim 1, wherein each of said microcapsules (3) is comprised of a matrix of the drug release rate controlling wall material, said matrix having the systemically active drug formulation distributed therethrough.
Claim 5
Dependent Claim
22 words
The bandage as defined by claim 1, wherein the systemically active drug formulation is soluble in the drug release rate controlling material.
Claim 6
Dependent Claim
21 words
The bandage as defined by claim 1, wherein the pressure-sensitive adhesive is permeable to passage of the systemically active drug formulation.
Claim 7
Dependent Claim
16 words
The bandage as defined by claim 1, wherein the drug formulation comprises a pharmacologically acceptable solvent.
Claim 8
Dependent Claim
17 words
The bandage as defined by claim 1, wherein said drug release rate controlling material is silicone rubber.
Claim 9
Dependent Claim
25 words
The bandage as defined by claim 1, wherein said drug release rate controlling material is a hydrophilic polymer of an ester of an olefinic acid.
Claim 10
Dependent Claim
27 words
The bandage as defined by claim 1, wherein the pressure-sensitive adhesive is adapted to provide a liquidtight adhesive seal between the skin or mucosa and the bandage.
Claim 11
Dependent Claim
23 words
The bandage as defined by claim 1, wherein the surface of a pressure-sensitive adhesive (3) is covered with a protective release coating (4).
Claim 12
Dependent Claim
24 words
The bandage as defined by claim 1, wherein the outer surface of the backing member (1) is coated with a low adhesion backsize (5).
Claim 13
Dependent Claim
21 words
The bandage as defined by claim 1, wherein said microcapsules have an average particle size of from 1 to 1,000 microns.
Claim 14
Dependent Claim
23 words
The bandage as defined by claim 1, wherein the adhesive face of the bandage has an area of 0.5 to 400 square centimeters.
References Cited (Backward Citations)
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Cited
US3339546A
Cited
US3328259A
Cited
US3444858A
Cited
US3520949A
Cited
US3464413A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-08-09 | 1975-02-08 | 1975-08-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-08-09 | 1979-02-08 | 1979-08-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-08-09 | 1983-02-08 | 1983-08-10 | $7700.00 | Window Closed / Lapsed |