Reactions system
Abstract
Abstract A CLOSED REACTION SYSTEM, PARTICULARLY ADAPTED TO THE SOLID-PHASE SYNTHESIS OF PEPTIDES, WHEREIN THE REAGENTS AND REACTANTS ARE TRANSFERRED FROM STORAGE VESSELS TO A METERING VESSEL, OR A REACTION VESSEL, WITHOUT CONTACTING PUMPS OR VALVES. THE STORAGE VESSELS ARE SELECTIVELY CONNECTED TO A PRESSURE SOURCE TO APPLY A PRESSURE HEAD TO THE REAGENT OR REAGENT THEREIN WHICH IS AT GREATER PRESSURE THAN THE PRESSURE HEAD PREVAILING IN THE METERING VESSEL OR REACTION VESSEL, CAUSING THE REAGENT OR REACTANT TO FLOW FROM THE STORAGE VESSEL TO THE METERING OR REACTION VESSEL. THE REAGENT OR REACTANT FLOW IS INTERRUPTED BY CONNECTING THE STORAGE VESSEL TO A PRESSURE SOURCE TO APPLY A PRESSURE HEAD TO THE REAGENT OR REACTANT THEREI OF LESS PRESSURE THAN THE PRESSURE HEAD PREVAILING IN THE METERING OR REACTION VESSEL. THE FLOW MAY BE INITIATED BY INTRODUCING A NON-REACTIVE OR INERT GAS INTO THE STORAGE VESSEL AND THE FLOW INTERRUPTED BY CONNECTING THE STORAGE VESSEL TO A SOURCE OF VACUUM OR BY INTRODUCING A NON-REACTIVE OR INERT GAS INTO THE METERING OR REACTION VESSEL OR PLACING THE METERING OR REACTION VESSEL ABOVE THE STORAGE VESSEL AND CONNECTING THE STORAGE VESSEL TO THE ATMOSPHERE.
Inventors
- 👤 Kay Brunfeldt
- 👤 Peter Roepstorff
- 👤 John Halstrom
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-01-18 | 1974-07-20 | 1975-01-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-01-18 | 1978-07-20 | 1979-01-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-01-18 | 1982-07-20 | 1983-01-19 | $7700.00 | Window Closed / Lapsed |