US3099600A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Chromatographic purification of heparin
Assignee: Ormonoterapia Richter SpA
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Filing: 1961-04-17
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Granted: 1963-07-30
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Expires: 1981-04-17
Abstract
No abstract record available.
Inventors
- 👤 Toccaceli Nazzareno
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:56
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/006; C08B37/0063; C08B37/0075
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
90 words
A METHOD OF PURIFYING HEPARIN COMPRISING DISSOLVING HEPARIN IN A BUFFERED SOLUTION HAVING A PH OF ABOUT 5,5-8,5; ADSORBING SAID HAPARIN SOLUTION ON AN ANION EXCHANGE MATERIAL SELECTED FROM THE GROUP CONSISTING OF DIETHYLAMINOETHYL-CELLULOSE AND TRIETHYLAMINOETHYL-CELLULOSE; ELUTING SAID ANION EXCHANGE MATERIAL AND ADSORBED HEPARIN WITH A SALT SOLUTION OF RELATIVELY LOW IONIC STRENGTH TO SELECTIVELY REMOVE THE LESS ACTIVE FRACTIONS OF SAID HEPARIN AND ELUTING SAID ANION EXCHANGE MATERIAL AND ADSORBED HEPARIN WITH A SECOND SALT SOLUTION OF RELATIVELY HIGH IONIC STRENGTH TO REMOVE THE MORE ACTIVE FRACTIONSS OF HEPARIN.
Claim 2
Independent Claim
90 words
A METHOD OF PURIFYING HEPARIN COMPRISING DISSOLVING HEPARIN IN A BUFFERED SOLUTION HAVING A PH OF ABOUT 5,5-8,5; ADSORBING SAID HAPARIN SOLUTION ON AN ANION EXCHANGE MATERIAL SELECTED FROM THE GROUP CONSISTING OF DIETHYLAMINOETHYL-CELLULOSE AND TRIETHYLAMINOETHYL-CELLULOSE; ELUTING SAID ANION EXCHANGE MATERIAL AND ADSORBED HEPARIN WITH A SALT SOLUTION OF RELATIVELY LOW IONIC STRENGTH TO SELECTIVELY REMOVE THE LESS ACTIVE FRACTIONS OF SAID HEPARIN AND ELUTING SAID ANION EXCHANGE MATERIAL AND ADSORBED HEPARIN WITH A SECOND SALT SOLUTION OF RELATIVELY HIGH IONIC STRENGTH TO REMOVE THE MORE ACTIVE FRACTIONSS OF HEPARIN.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1966-07-29 | 1967-01-28 | 1967-07-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1970-07-29 | 1971-01-28 | 1971-07-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1974-07-29 | 1975-01-28 | 1975-07-30 | $7700.00 | Window Closed / Lapsed |