Patent US3417361A successfully refreshed from Google Patents.
US2979438A
Expired / Lapsed
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Extraction of collagen
Assignee: United Shoe Machinery Corp
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Filing: 1958-08-07
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Granted: 1961-04-11
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Expires: 1978-08-07
Abstract
No abstract record available.
Inventors
- 👤 John H Highberger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 18:46
CPC Classifications
C; C09; C09H; C09H3/00; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
158 words
A PROCESS FOR EXTRACTING COLLAGEN IN SOLUBLE, RECONSTITUTABLE FORM FROM SKIN MATERIAL WHICH COMPRISES IMMERSING THE SKIN MATERIAL IN AN AQUEOUS SOLUTION CONTAINING THE ENZYME FRACTION SALTED OUT FROM A PH 4 TO 5 AQUEOUS EXTRACT OF PANCREAS BY AMMONIUM SULFATE BY INCREASING THE CONCENTRATION OF AMMONIUM SULFATE FROM AN INITIAL VALUE OF 20% OF SATURATION TO A FINAL VALUE OF 40% OF SATURATION, INCUBATING THE SKIN MATERIAL IN SAID SOLUTION AT A PH IN THE RANGE OF 7 TO 9 FOR AT LEAST 1/4 OF AN HOUR AT APPROXIMATELY 37*C. TO BREAK THE LINKAGES HOLDING COLLAGEN AGAINST SOLLUTION, REMOVING SAID SKIN MATERIAL FROM SAID SOLUTION BEFORE SUBSTANTIAL DEGRADATION OF THE COLLAGEN AND SOAKING THE SKIN MATERIAL IN AN AQUEOUS EXTRACTION BATH HAVING A PH OF 3 TO 4.5 AND AN IONIC STRENGTH BELOW 0.5 TO DISSOLVE A HIGH PORTION OF THE COLLAGEN CONTENT OF SAID SKIN MATERIAL AND TO FORM A CONCENTRATED SOLUTION OF ACID SOLUBLE COLLAGEN.
Claim 2
Dependent Claim
158 words
A PROCESS FOR EXTRACTING COLLAGEN IN SOLUBLE, RECONSTITUTABLE FORM FROM SKIN MATERIAL WHICH COMPRISES IMMERSING THE SKIN MATERIAL IN AN AQUEOUS SOLUTION CONTAINING THE ENZYME FRACTION SALTED OUT FROM A PH 4 TO 5 AQUEOUS EXTRACT OF PANCREAS BY AMMONIUM SULFATE BY INCREASING THE CONCENTRATION OF AMMONIUM SULFATE FROM AN INITIAL VALUE OF 20% OF SATURATION TO A FINAL VALUE OF 40% OF SATURATION, INCUBATING THE SKIN MATERIAL IN SAID SOLUTION AT A PH IN THE RANGE OF 7 TO 9 FOR AT LEAST 1/4 OF AN HOUR AT APPROXIMATELY 37*C. TO BREAK THE LINKAGES HOLDING COLLAGEN AGAINST SOLLUTION, REMOVING SAID SKIN MATERIAL FROM SAID SOLUTION BEFORE SUBSTANTIAL DEGRADATION OF THE COLLAGEN AND SOAKING THE SKIN MATERIAL IN AN AQUEOUS EXTRACTION BATH HAVING A PH OF 3 TO 4.5 AND AN IONIC STRENGTH BELOW 0.5 TO DISSOLVE A HIGH PORTION OF THE COLLAGEN CONTENT OF SAID SKIN MATERIAL AND TO FORM A CONCENTRATED SOLUTION OF ACID SOLUBLE COLLAGEN.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1964-04-10 | 1964-10-10 | 1965-04-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1968-04-10 | 1968-10-10 | 1969-04-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1972-04-10 | 1972-10-10 | 1973-04-11 | $7700.00 | Window Closed / Lapsed |