Patent US2747021A successfully refreshed from Google Patents.
US2809917A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sustained release pharmaceutical tablets
Assignee: Individual
•
Filing: 1955-10-17
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Granted: 1957-10-15
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Expires: 1975-10-17
Abstract
No abstract record available.
Inventors
- 👤 Victor M Hermelin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:50
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/2086; A61K9/209; A61K9/2004; A61K9/2009; A61K9/2013
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
244 words
THE METHOD OF MAKING A LAMINATED TABLET HAVING A LAYER CONTAINING AN IMMEDIATE RELEASE MEDICATED PREPARATION AND A LAYER CONTAINING A DELAYED RELEASE MEDICATED PREPARATION HAVING A SLOW BUT CONTINUOUS AND ATTENUATED SOLUBALITY IN THE GASTRO-INTESTINAL TRACT, WHICH METHOD COMPRISES INTIMATELY MIXING A POWDERED DRUG AND AN ENTERIC WATER INSOLUBLE EXCIPIENT TO PRODUCE A PASTY MASS, DRYING THE MASS SLOWLY WITHOUT AGITATION IN SUCH A MANNER AS TO PRODUCE A ROUGH GRANULAR MATERIAL, BREAKING UP THE ROUGH GRANULAR MATERIAL BY LIGHT CRUSHING , WHEREBY TO REDUCE IT TO GRANULAR PARTICLES, SAID MIXING, DRYING AND CRUSHING OPERATIONS CONSTITUTING ONE CYCLE, AND REMIXING THE GRANULAR PARTICLES WITH AN ADDITIONAL QUANTITY OF THE EXCIPIENT TO PRODUCE A PASTY MASS, REDRYING SUCH PASTY MASS SLOWLY AND WITHOUT AGITATION IN SUCH A MANNER AS TO PRODUCE A GRANULAR MATERIAL, AGAIN BREAKING UP THE ROUGH GRANULAR MATERIAL BY LIGHT CRUSHING, WHEREBY TO REDUCE IT AGAIN TO GRANULAR PARTICLES, SAID SECOND MIXING, DRYING AND CRUSHING OPERATION CONSTITUTING A SECOND CYCLE, SAID PROCESS CONSISTING OF NOT LESS THAN THREE NOR MORE THAN FIFTEEN MIXING, CRUSHING AND DRYING CYCLES REPEATED IN SUCCESSIVE ORDER WHEREBY TO PRODUCE THE DELAYED RELEASE MEDICATED PREPARATION, INTRODUCING ONE OF SAID MEDICATED PREPARATIONS INTO A DIE CAVITY AND COMPRESSING SAME TO FORM A FIRST SOLID LAYER, INTRODUCING THE OTHER OF SAID PREPARATIONS INTO THE CAVITY ON TOP OF THE COMPRESSED FIRST PREP ARATION, AND THEREAFTER COMPRESSING SAID OTHER PREPARATION INTO A SECOND SOLID LAYER WHICH ADHERES FIRMLY TO SAID
Claim 2
Independent Claim
244 words
THE METHOD OF MAKING A LAMINATED TABLET HAVING A LAYER CONTAINING AN IMMEDIATE RELEASE MEDICATED PREPARATION AND A LAYER CONTAINING A DELAYED RELEASE MEDICATED PREPARATION HAVING A SLOW BUT CONTINUOUS AND ATTENUATED SOLUBALITY IN THE GASTRO-INTESTINAL TRACT, WHICH METHOD COMPRISES INTIMATELY MIXING A POWDERED DRUG AND AN ENTERIC WATER INSOLUBLE EXCIPIENT TO PRODUCE A PASTY MASS, DRYING THE MASS SLOWLY WITHOUT AGITATION IN SUCH A MANNER AS TO PRODUCE A ROUGH GRANULAR MATERIAL, BREAKING UP THE ROUGH GRANULAR MATERIAL BY LIGHT CRUSHING , WHEREBY TO REDUCE IT TO GRANULAR PARTICLES, SAID MIXING, DRYING AND CRUSHING OPERATIONS CONSTITUTING ONE CYCLE, AND REMIXING THE GRANULAR PARTICLES WITH AN ADDITIONAL QUANTITY OF THE EXCIPIENT TO PRODUCE A PASTY MASS, REDRYING SUCH PASTY MASS SLOWLY AND WITHOUT AGITATION IN SUCH A MANNER AS TO PRODUCE A GRANULAR MATERIAL, AGAIN BREAKING UP THE ROUGH GRANULAR MATERIAL BY LIGHT CRUSHING, WHEREBY TO REDUCE IT AGAIN TO GRANULAR PARTICLES, SAID SECOND MIXING, DRYING AND CRUSHING OPERATION CONSTITUTING A SECOND CYCLE, SAID PROCESS CONSISTING OF NOT LESS THAN THREE NOR MORE THAN FIFTEEN MIXING, CRUSHING AND DRYING CYCLES REPEATED IN SUCCESSIVE ORDER WHEREBY TO PRODUCE THE DELAYED RELEASE MEDICATED PREPARATION, INTRODUCING ONE OF SAID MEDICATED PREPARATIONS INTO A DIE CAVITY AND COMPRESSING SAME TO FORM A FIRST SOLID LAYER, INTRODUCING THE OTHER OF SAID PREPARATIONS INTO THE CAVITY ON TOP OF THE COMPRESSED FIRST PREP ARATION, AND THEREAFTER COMPRESSING SAID OTHER PREPARATION INTO A SECOND SOLID LAYER WHICH ADHERES FIRMLY TO SAID
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1960-10-14 | 1961-04-15 | 1961-10-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1964-10-14 | 1965-04-15 | 1965-10-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1968-10-14 | 1969-04-15 | 1969-10-15 | $7700.00 | Window Closed / Lapsed |