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US20100228285A1 Active / In Force US ⏱️ 3.2 years remaining

Medical device for modification of left atrial appendage and related systems and methods

Assignee: Coherex Medical Inc
•
Filing: 2010-01-08
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Granted: —
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Expires: 2030-01-08
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Abstract

Abstract Medical devices, systems and methods for modifying a left atrial appendage (“LAA”). In one embodiment, a medical device system includes a jailing member or structure positioned over the ostium of an LAA and at least one tissue growth member positioned within the LAA and retained within the LAA by the jailing member. In another embodiment, a medical device includes an atrial stent coupled with a patch that is configured to cover the ostium of an LAA. The patch may have a tissue growth member associated therewith. In another embodiment, the patch may include an open-cell frame which may be used as a jailing member or structure.

Inventors

  • 👤 Scott D. Miles
  • 👤 Daryl R. Edmiston

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 15:30
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12131; A61B17/1214; A61B17/1215; A61B17/00234; A61B17/0057; A61B17/04; A61B17/0401; A61B17/06; A61B17/06166; A61B17/12027; A61B17/12031; A61B17/1204; A61B17/12099; A61B17/12122; A61B17/12159; A61B17/12168; A61B17/12172; A61B17/122; A61B17/0487; A61B2017/00238; A61B2017/00243; A61B2017/00526; A61B2017/00575; A61B2017/00579; A61B2017/00588; A61B2017/00592; A61B2017/00597; A61B2017/00601; A61B2017/0061; A61B2017/00632; A61B2017/00831; A61B2017/00867; A61B2017/00884; A61B2017/0409; A61B2017/0412; A61B2017/0414; A61B2017/0427; A61B2017/0437; A61B2017/0446; A61B2017/0448; A61B2017/0459; A61B2017/0464; A61B2017/1205; Y; Y10; Y10T; Y10T29/00; Y10T29/49; Y10T29/49826

Claims Analysis

Total Claims: 34
Claim 1
Independent Claim 75 words
1 . A medical device system for modification of a left atrial appendage (LAA) comprising: a medical device having a framework including a jailing portion configured to be positioned against a sidewall of the left atrium of the heart and over an ostium of the LAA and a tissue growth member configured to be retained within the LAA, the tissue growth member configured to be separate and discreet from the framework of the medical device.
Claim 2
Dependent Claim 75 words
1 . A medical device system for modification of a left atrial appendage (LAA) comprising: a medical device having a framework including a jailing portion configured to be positioned against a sidewall of the left atrium of the heart and over an ostium of the LAA and a tissue growth member configured to be retained within the LAA, the tissue growth member configured to be separate and discreet from the framework of the medical device.
Claim 3
Dependent Claim 22 words
2 . The medical device system of claim 1 , wherein the tissue growth member comprises a plurality of tissue growth elements.
Claim 4
Dependent Claim 25 words
3 . The medical device system of claim 2 , wherein the plurality of tissue growth elements are coupled to one another via a tether.
Claim 5
Dependent Claim 20 words
4 . The medical device system of claim 1 , wherein the tissue growth member comprises a self expanding foam.
Claim 6
Dependent Claim 22 words
5 . The medical device system of claim 1 , wherein the framework is formed of a material comprising a nickel-titanium alloy.
Claim 7
Dependent Claim 52 words
6 . The medical device system of claim 1 , wherein the framework is formed as a stent structure sized and configured to be positioned within the left atrium of the heart and biased against the walls of the left atrium with the jailing portion positioned over an ostium of the LAA.
Claim 8
Dependent Claim 36 words
7 . The medical device system of claim 1 , wherein the medical device further includes an anchoring portion coupled with the framework, the anchoring portion being sized and configured to engage tissue within an LAA.
Claim 9
Dependent Claim 28 words
8 . The medical device system of claim 7 , wherein the medical device further includes a biasing member coupled between the anchoring portion and the jailing portion.
Claim 10
Dependent Claim 33 words
9 . The medical device system of claim 8 , wherein the anchoring portion further includes a plurality of anchor legs having a coiled portion configured to engage the tissue of an LAA.
Claim 11
Dependent Claim 21 words
10 . The medical device system of claim 9 , further comprising one or more nubs associated with each coiled portion.
Claim 12
Dependent Claim 26 words
11 . The medical device system of claim 1 , wherein the jailing portion is formed of a plurality of frame segments that are substantially coplanar.
Claim 13
Dependent Claim 37 words
12 . The medical device system of claim 1 , wherein the medical device is configured to exhibit a first, constrained configuration within a delivery mechanism and a second, deployed configuration when released from the delivery mechanism.
Claim 14
Dependent Claim 73 words
13 . A medical device configured to modify a left atrial appendage, comprising: a patch including a framework and a tissue growth member, the patch being sized and configured to extend against a sidewall of a left atrium to cover an ostium of the left atrial appendage; and at least one looped structure extending from the patch and configured to engage and bias against the sidewall of the left atrium of the heart.
Claim 15
Dependent Claim 73 words
13 . A medical device configured to modify a left atrial appendage, comprising: a patch including a framework and a tissue growth member, the patch being sized and configured to extend against a sidewall of a left atrium to cover an ostium of the left atrial appendage; and at least one looped structure extending from the patch and configured to engage and bias against the sidewall of the left atrium of the heart.
Claim 16
Dependent Claim 40 words
14 . The medical device of claim 13 , wherein the at least one looped structure includes a first loop extending from a first portion of the patch and a second loop extending from a second portion of the patch.
Claim 17
Dependent Claim 24 words
15 . The medical device of claim 13 , wherein the at least one looped structure includes a framework defining an open cell structure.
Claim 18
Dependent Claim 22 words
16 . The medical device of claim 13 , wherein the tissue growth member is formed of a porous foam or fabric.
Claim 19
Dependent Claim 16 words
17 . The medical device of claim 13 , wherein the framework comprises a nickel-titanium alloy.
Claim 20
Dependent Claim 19 words
18 . The medical device of claim 13 , further comprising a plurality of anchors associated with the patch.
Claim 21
Dependent Claim 69 words
19 . A medical device configured to modify a left atrial appendage comprising: a framework sized and configured to bias against the sidewall of the left atrium of the heart and over the ostium of a left atrial appendage; and a tissue growth member on at least a portion of the framework, the tissue growth member being sized and configured to cover the ostium of a left atrial appendage.
Claim 22
Dependent Claim 69 words
19 . A medical device configured to modify a left atrial appendage comprising: a framework sized and configured to bias against the sidewall of the left atrium of the heart and over the ostium of a left atrial appendage; and a tissue growth member on at least a portion of the framework, the tissue growth member being sized and configured to cover the ostium of a left atrial appendage.
Claim 23
Dependent Claim 48 words
20 . The medical device of claim 19 , wherein the framework includes a radial inner periphery and a radial outer periphery, and wherein the tissue growth member is disposed substantially over the entirety of at least one of the radial inner periphery and the radial outer periphery.
Claim 24
Dependent Claim 22 words
21 . The medical device of claim 19 , wherein the tissue growth member is formed of a porous foam or fabric.
Claim 25
Dependent Claim 16 words
22 . The medical device of claim 19 , wherein the framework comprises a nickel-titanium alloy.
Claim 26
Dependent Claim 19 words
23 . The medical device of claim 19 , further comprising a plurality of anchors associated with the framework.
Claim 27
Dependent Claim 65 words
24 . A method of modifying a left atrial appendage, the method comprising: positioning a jailing member over the ostium of a left atrial appendage; inserting a catheter through an opening within the jailing member; disposing at least one tissue growth member within the left atrial appendage; and retaining the at least one tissue growth member within the left atrial appendage with the jailing member.
Claim 28
Dependent Claim 65 words
24 . A method of modifying a left atrial appendage, the method comprising: positioning a jailing member over the ostium of a left atrial appendage; inserting a catheter through an opening within the jailing member; disposing at least one tissue growth member within the left atrial appendage; and retaining the at least one tissue growth member within the left atrial appendage with the jailing member.
Claim 29
Dependent Claim 39 words
25 . The method according to claim 24 , wherein positioning a jailing member over the ostium of a left atrial appendage includes engaging walls of the left atrial appendage with an anchoring member coupled with the jailing member.
Claim 30
Dependent Claim 23 words
26 . The method according to claim 25 , further comprising providing a tensile bias between the anchoring member and the jailing member.
Claim 31
Dependent Claim 86 words
27 . The method according to claim 24 , wherein positioning a jailing member over the ostium of a left atrial appendage includes delivering the jailing member to the left atrial appendage with a first catheter, and wherein inserting a catheter through an opening within the jailing member and disposing at least one tissue growth member within the left atrial appendage includes inserting a second catheter through an opening within the jailing member and delivering the at least one tissue growth member with the second catheter.
Claim 32
Dependent Claim 57 words
28 . The method according to claim 27 , further comprising advancing the first catheter through a primary catheter to access the left atrial appendage, withdrawing the first catheter from the primary catheter subsequent delivering the jailing member to the left atrial appendage, and advancing the second catheter through the primary catheter subsequent withdrawing the first catheter.
Claim 33
Dependent Claim 37 words
29 . The method according to claim 24 , wherein disposing at least one tissue growth member within the left atrial appendage further includes disposing a plurality of a tissue growth elements within the left atrial appendage.
Claim 34
Dependent Claim 21 words
30 . The method according to claim 29 , further comprising connecting the plurality of tissue growth members with a tether.

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