US20030023200A1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Partial aortic occlusion devices and methods for cerebral perfusion augmentation
Assignee: Zoll Circulation Inc
•
Filing: 2001-04-24
•
Granted: —
•
Expires: 2021-04-24
Abstract
Abstract Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.
Inventors
- 👤 Denise Barbut
- 👤 Peter Keith
- 👤 Steven Berhow
- 👤 Jon St. Germain
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:04
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12027; A61B17/1204; A61B17/12045; A61B17/12036; A61B17/12099; A61B17/12109; A61B17/12131; A61B17/12136; A61B17/1214; A61B17/12145; A61B17/12181; A61B17/1219; A61B5/00; A61B5/02; A61B5/021; A61B5/0215; A61B5/40; A61B5/4076; A61B6/00; A61B6/48; A61B6/481; A61F; A61F7/00; A61F7/12; A61M; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M25/003; A61M25/0067; A61M25/0068; A61M25/008; A61M25/0082; A61M25/01; A61M25/0105; A61M25/0133; A61M25/0147; A61M25/10; A61M25/1011; A61B17/22; A61B2017/22051; A61B2017/22054; A61B90/00; A61B90/39; A61B2090/3966; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2002/068; A61F2007/126; A61M2025/0001; A61M2025/0002; A61M2025/0034; A61M2025/0073; A61M2025/0081; A61M2025/1043; A61M2025/1052; A61M2210/00; A61M2210/12; A61M2210/127; A61M2230/00; A61M2230/005; A61M2230/30; A61M25/0032; A61M25/0069; A61M25/0074; A61M25/06; A61M25/0662
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
82 words
1 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member downstream from the takeoff of the brachiocephalic artery; expanding the expandable member to at least partially obstruct blood flow in the aorta; measuring cerebral blood flow; and adjusting the expansion of the expandable member based on measured cerebral blood flow.
Claim 2
Dependent Claim
82 words
1 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member downstream from the takeoff of the brachiocephalic artery; expanding the expandable member to at least partially obstruct blood flow in the aorta; measuring cerebral blood flow; and adjusting the expansion of the expandable member based on measured cerebral blood flow.
Claim 3
Dependent Claim
39 words
2 . The method of claim 1 , further comprising the step of advancing a medical instrument through a lumen of the catheter, beyond a distal port of the catheter, and into an artery that branches from the aorta.
Claim 4
Dependent Claim
24 words
3 . The method of claim 1 , further comprising the step of measuring blood pressure in the proximal aorta and/or the distal aorta.
Claim 5
Dependent Claim
24 words
4 . The method of claim 1 , wherein blood pressure in the proximal aorta increases and blood pressure in the distal aorta decreases.
Claim 6
Dependent Claim
15 words
5 . The method of claim 1 , wherein the expandable member comprises a balloon.
Claim 7
Dependent Claim
21 words
6 . The method of claim 1 , wherein the expanded member includes an aperture through which blood flows during use.
Claim 8
Dependent Claim
31 words
7 . The method of claim 1 , wherein the expanded member allows blood flow through an area between the lumen of the aorta and outer dimensions of the expandable member.
Claim 9
Dependent Claim
23 words
8 . The method of claim 1 , wherein the step of expanding the expandable member includes maintaining the expanded member during systole.
Claim 10
Dependent Claim
93 words
9 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, a first expandable member mounted on the distal region, and a second expandable member mounted on the distal region proximal the first expandable member; locating the first expandable member upstream from the takeoff of the renal arteries; locating the second expandable member downstream from the takeoff of the renal arteries; and expanding the second expandable member to partially occlude blood flow in the aorta.
Claim 11
Dependent Claim
93 words
9 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, a first expandable member mounted on the distal region, and a second expandable member mounted on the distal region proximal the first expandable member; locating the first expandable member upstream from the takeoff of the renal arteries; locating the second expandable member downstream from the takeoff of the renal arteries; and expanding the second expandable member to partially occlude blood flow in the aorta.
Claim 12
Dependent Claim
25 words
10 . The method of claim 9 , further comprising the step of expanding the first constrictor to partially occlude blood flow in the aorta.
Claim 13
Dependent Claim
21 words
11 . The method of claim 10 , further comprising the step of partially reducing the expansion of the second constrictor.
Claim 14
Dependent Claim
17 words
12 . The method of claim 9 , further comprising the step of measuring cerebral blood flow.
Claim 15
Dependent Claim
26 words
13 . The method of claim 10 , further comprising the step of adjusting the expansion of the second constrictor based on measured cerebral blood flow.
Claim 16
Dependent Claim
39 words
14 . The method of claim 9 , further comprising the step of advancing a medical instrument through a lumen of the catheter, beyond a distal port of the catheter, and into an artery that branches from the aorta.
Claim 17
Dependent Claim
35 words
15 . The method of claim 9 , further comprising the step of measuring blood pressure in at least one of the proximal aorta, the distal aorta, and between the first and second expandable members.
Claim 18
Dependent Claim
24 words
16 . The method of claim 9 , wherein blood pressure in the proximal aorta increases and blood pressure in the distal aorta decreases.
Claim 19
Dependent Claim
16 words
17 . The method of claim 9 , wherein the first and second constrictors are balloons.
Claim 20
Dependent Claim
34 words
18 . The method of claim 9 , wherein the first and second constrictors, when expanded, allow blood flow through an area between the lumen of the aorta and outer dimensions of the constrictors.
Claim 21
Dependent Claim
24 words
19 . The method of claim 9 , wherein the first expandable member is located upstream from the takeoff of the superior mesenteric artery.
Claim 22
Dependent Claim
42 words
20 . The method of claim 9 , wherein the catheter includes pressure measuring capabilities disposed between the first and second expandable members, and wherein the method further comprises the step of measuring blood pressure between the first and second expandable members.
Claim 23
Dependent Claim
35 words
21 . The method of claim 9 , wherein the catheter further comprises a stiffening element, and wherein the method further comprises the step of inserting the stiffening element into a lumen of the catheter.
Claim 24
Dependent Claim
93 words
22 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal end, a distal end, a first expandable member mounted on the distal end, and a second expandable member mounted on the distal end proximal the first expandable member; locating the first expandable member upstream from the takeoff of the renal arteries; locating the second expandable member downstream from the takeoff of the renal arteries; and expanding the first expandable member to partially occlude blood flow in the aorta.
Claim 25
Dependent Claim
93 words
22 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal end, a distal end, a first expandable member mounted on the distal end, and a second expandable member mounted on the distal end proximal the first expandable member; locating the first expandable member upstream from the takeoff of the renal arteries; locating the second expandable member downstream from the takeoff of the renal arteries; and expanding the first expandable member to partially occlude blood flow in the aorta.
Claim 26
Dependent Claim
24 words
23 . The method of claim 22 , wherein the first expandable member is located upstream from the takeoff of the superior mesenteric artery.
Claim 27
Dependent Claim
42 words
24 . The method of claim 22 , wherein the catheter includes pressure measuring capabilities disposed between the first and second expandable members, and wherein the method further comprises the step of measuring blood pressure between the first and second expandable members.
Claim 28
Dependent Claim
35 words
25 . The method of claim 22 , wherein the catheter further comprises a stiffening element, and wherein the method further comprises the step of inserting the stiffening element into a lumen of the catheter.
Claim 29
Dependent Claim
25 words
26 . The method of claim 22 , further comprising the step of expanding the second constrictor to partially occlude blood flow in the aorta.
Claim 30
Dependent Claim
21 words
27 . The method of claim 26 , further comprising the step of partially reducing the expansion of the first constrictor.
Claim 31
Dependent Claim
17 words
28 . The method of claim 22 , further comprising the step of measuring cerebral blood flow.
Claim 32
Dependent Claim
71 words
29 . A medical device for partial aortic occlusion for cerebral perfusion augmentation, comprising: an elongate member having proximal and distal ends; a first expandable member mounted at the distal end of the elongate member a second expandable member mounted at the distal end of the elongate member proximal the first expandable member; and a pressure measuring device operable to measure blood pressure in the aorta upstream the second expandable member.
Claim 33
Dependent Claim
71 words
29 . A medical device for partial aortic occlusion for cerebral perfusion augmentation, comprising: an elongate member having proximal and distal ends; a first expandable member mounted at the distal end of the elongate member a second expandable member mounted at the distal end of the elongate member proximal the first expandable member; and a pressure measuring device operable to measure blood pressure in the aorta upstream the second expandable member.
Claim 34
Dependent Claim
31 words
30 . The device of claim 29 , further comprising a first centering mechanism disposed about the first expandable member for centering the first expandable member within the aorta when deployed.
Claim 35
Dependent Claim
31 words
31 . The device of claim 29 , further comprising a second centering mechanism disposed about the second expandable member for centering the second expandable member within the aorta when deployed.
Claim 36
Dependent Claim
28 words
32 . The device of claim 29 , wherein the pressure measuring device is a pressure tube carried by the catheter and proximally connected to a pressure monitor.
Claim 37
Dependent Claim
24 words
33 . The device of claim 29 , wherein the pressure measuring device is a manometer mounted at the distal end of the catheter.
Claim 38
Dependent Claim
17 words
34 . The device of claim 29 , wherein the first and second expandable members are balloons.
Claim 39
Dependent Claim
30 words
35 . The device of claim 29 , wherein the first and second expandable members are cylindrical expandable balloons, each having an outer surface, a lumen, and an enclosed chamber.
Claim 40
Dependent Claim
22 words
36 . The device of claim 29 , wherein the pressure measuring device is disposed between the first and second expandable members.
Claim 41
Dependent Claim
23 words
37 . The device of claim 29 , further comprising a stiffening element that is insertable into a lumen of the elongate member.
Claim 42
Dependent Claim
27 words
38 . The method of claim 1 , wherein the first expandable member is located upstream from the takeoff of the renal arteries and superior mesenteric artery.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.