US20030018344A1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical device and method of embolizing bronchus or bronchiole
Assignee: Olympus Corp
•
Filing: 2002-07-19
•
Granted: —
•
Expires: 2022-07-19
Abstract
Abstract To provide a medical device and a method both of which can suitably embolize a bronchus in a target part by embolizing the bronchus with (at least a part of) a living tissue during surgical treatment of lung emphysema. For example, an injection material is injected into a submucosa by the use of a syringe, and in the injected part, a swelling swollen into the internal cavity of the bronchus is formed to tightly seal the living tissue of the bronchus or a bronchiole, thereby embolizing a target bronchus.
Inventors
- 👤 Hinako Kaji
- 👤 Kunihide Kaji
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:52
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12104; A61B17/12009; A61B17/12013; A61B17/12131; A61B17/12136; A61B17/12181; A61B17/12186; A61B2017/1205; A61B17/22; A61B2017/22051; A61B2017/22065
Claims Analysis
Total Claims: 80
Claim 1
Independent Claim
42 words
1 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a shape change inducing portion for changing a shape of an internal cavity of the bronchus/bronchiole by causing a tissue of the bronchus/bronchiole to adhere closely to each other.
Claim 2
Dependent Claim
42 words
1 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a shape change inducing portion for changing a shape of an internal cavity of the bronchus/bronchiole by causing a tissue of the bronchus/bronchiole to adhere closely to each other.
Claim 3
Dependent Claim
38 words
2 . The medical device according to claim 1 , wherein the shape change inducing portion includes an injection portion for injecting an injection material which swells a mucosa of the bronchus/bronchiole into a submucosa of the bronchus/bronchiole.
Claim 4
Dependent Claim
28 words
3 . The medical device according to claim 2 , wherein the injection material is selected from a group consisting of a bioadhesive and a highly viscous material.
Claim 5
Dependent Claim
17 words
4 . The medical device according to claim 3 , wherein the bioadhesive contains a fibrin adhesive.
Claim 6
Dependent Claim
17 words
5 . The medical device according to claim 3 , wherein the highly viscous material contains collagen.
Claim 7
Dependent Claim
21 words
6 . The medical device according to claim 2 , wherein the injection material contains a solid component of high biocompatibility.
Claim 8
Dependent Claim
30 words
7 . The medical device according to claim 6 , wherein the solid component of high biocompatibility is selected from a group consisting of silicone, metal particles, apatite and β-TCP.
Claim 9
Dependent Claim
35 words
8 . The medical device according to claim 2 , wherein the injection material is a material which changes to at least a partial solid form by addition of a curing agent to the material.
Claim 10
Dependent Claim
24 words
9 . The medical device according to claim 8 , wherein the at least a partial solid form is a gel of high viscosity.
Claim 11
Dependent Claim
48 words
10 . The medical device according to claim 2 , wherein the shape change inducing portion further includes an inserting portion to be inserted into the bronchus/bronchiole, the inserting portion having a channel through which to insert the injection portion, between its proximal portion and its leading portion.
Claim 12
Dependent Claim
31 words
11 . The medical device according to claim 10 , further comprising a fixing portion for fixing the leading portion of the inserting portion in the internal cavity of the bronchus/bronchiole.
Claim 13
Dependent Claim
53 words
12 . The medical device according to claim 11 , wherein the fixing portion includes a hollow element having a shape to be attached to the leading portion of the inserting portion, and a pressure element fixed to the hollow element and constructed to expand and press the internal cavity of the bronchus/bronchiole.
Claim 14
Dependent Claim
41 words
13 . The medical device according to claim 11 , wherein the injection portion has a hollow needle for puncturing the submucosa, the fixing portion including a tube which constitutes a guide passage for guiding the hollow needle to the submucosa.
Claim 15
Dependent Claim
42 words
14 . The medical device according to claim 1 , further comprising an adhesion holding portion to be placed in an adhered portion in which the tissue adheres closely to adjacent tissue for holding a state of adhesion of the adhered portion.
Claim 16
Dependent Claim
26 words
15 . The medical device according to claim 14 , wherein the adhesion holding portion is a coil or a clip which sutures the adhered portion.
Claim 17
Dependent Claim
44 words
16 . The medical device according to claim 1 , wherein the shape change inducing portion includes a holding portion which holds a tissue proliferation material for proliferating a mucosa of the bronchus/bronchiole, in order to place the tissue proliferation material in the bronchus/bronchiole.
Claim 18
Dependent Claim
29 words
17 . The medical device according to claim 16 , wherein the tissue proliferation material has a property which proliferates a granulation tissue by means of a biological reaction.
Claim 19
Dependent Claim
19 words
18 . The medical device according to claim 17 , wherein the tissue proliferation material has an anchor-like shape.
Claim 20
Dependent Claim
48 words
19 . The medical device according to claim 16 , wherein the shape change inducing portion further includes an inserting portion to be inserted into the bronchus/bronchiole, the inserting portion having a channel through which to insert the injection portion, between its proximal portion and its leading portion.
Claim 21
Dependent Claim
39 words
20 . The medical device according to claim 1 , wherein the shape change inducing portion includes a portion which peels and dissects a mucosa of the bronchus/bronchiole, and a suturing portion which sutures the peeled and dissected mucosa.
Claim 22
Dependent Claim
45 words
21 . The medical device according to claim 20 , wherein the portion which peels and dissects is a medical treatment element selected from a group consisting of a needle, a knife, scissors, a knife having a high-frequency electricity, a spatula and a laser knife.
Claim 23
Dependent Claim
26 words
22 . The medical device according to claim 21 , wherein the sutured portion is selected from a group consisting of a coil and a clip.
Claim 24
Dependent Claim
34 words
23 . The medical device according to claim 1 , wherein the shape change inducing portion includes a portion which is disposed outside a wall of the bronchus/bronchiole and presses and embolizes the bronchus/bronchiole.
Claim 25
Dependent Claim
47 words
24 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a portion which embolizes and releases the bronchus/bronchiole; and a spraying portion for spraying in the bronchus/ bronchiole a spray material which causes inflammation in a tissue of the bronchus/bronchiole to embolize the same.
Claim 26
Dependent Claim
47 words
24 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a portion which embolizes and releases the bronchus/bronchiole; and a spraying portion for spraying in the bronchus/ bronchiole a spray material which causes inflammation in a tissue of the bronchus/bronchiole to embolize the same.
Claim 27
Dependent Claim
70 words
25 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a portion which artificially inflates and deflates a lung; a portion which embolizes and releases the bronchus/bronchiole; and an observing portion provided in a pleural cavity for observing a surface of the lung with the bronchus/ bronchiole embolized by the embolization and release portion and with the lung inflated or deflated by the inflating and deflating portion.
Claim 28
Dependent Claim
70 words
25 . A medical device which embolizes a bronchus/bronchiole of a subject, comprising: a portion which artificially inflates and deflates a lung; a portion which embolizes and releases the bronchus/bronchiole; and an observing portion provided in a pleural cavity for observing a surface of the lung with the bronchus/ bronchiole embolized by the embolization and release portion and with the lung inflated or deflated by the inflating and deflating portion.
Claim 29
Dependent Claim
37 words
26 . An embolization device for a bronchus/bronchiole of a subject, the embolization device comprising: means for embolizing an internal cavity of the bronchus/bronchiole by causing a tissue of the bronchus/bronchiole to adhere closely to each other.
Claim 30
Dependent Claim
37 words
26 . An embolization device for a bronchus/bronchiole of a subject, the embolization device comprising: means for embolizing an internal cavity of the bronchus/bronchiole by causing a tissue of the bronchus/bronchiole to adhere closely to each other.
Claim 31
Dependent Claim
34 words
27 . The embolization device according to claim 26 , wherein the means comprises: a liquid embolization material compatible to the tissue; and an injection device for injecting the embolization material into the tissue.
Claim 32
Dependent Claim
24 words
28 . The embolization device according to claim 27 , wherein the injection device is capable of passing through a channel of a bronchoscope.
Claim 33
Dependent Claim
22 words
29 . The embolization device according to claim 27 , wherein the injection device has a function to adjust an injection position.
Claim 34
Dependent Claim
42 words
30 . The embolization device according to claim 26 , wherein a placing object having a property to cause inflammation in a portion of the tissue is placed in a portion where the tissue is to be adhered closely to each other.
Claim 35
Dependent Claim
24 words
31 . The embolization device according to claim 30 , wherein the placing object has a shape capable of being attached to a mucosa.
Claim 36
Dependent Claim
17 words
32 . The embolization device according to claim 30 , wherein the placing object is a powder.
Claim 37
Dependent Claim
29 words
33 . The embolization device according to claim 26 , wherein the tissue is adhered closely to each other by changing a shape of a mucosa of the bronchus/bronchiole.
Claim 38
Dependent Claim
21 words
34 . The embolization device according to claim 33 , wherein an adhered portion can be fixed by a coil-like element.
Claim 39
Dependent Claim
21 words
35 . The embolization device according to claim 33 , wherein the mucosa of the bronchus/bronchiole can be cut and sutured.
Claim 40
Dependent Claim
84 words
36 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising: a catheter having, at its leading end, a puncture portion capable of puncturing a mucosa of the bronchus/bronchiole and, at its distal end, a connection portion to which to connect a syringe; and an injection material for inflating an internal cavity of the bronchus/bronchiole being capable of being injected into a submucosa of the bronchus/bronchiole via the puncture portion by the syringe connected to the connection portion.
Claim 41
Dependent Claim
84 words
36 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising: a catheter having, at its leading end, a puncture portion capable of puncturing a mucosa of the bronchus/bronchiole and, at its distal end, a connection portion to which to connect a syringe; and an injection material for inflating an internal cavity of the bronchus/bronchiole being capable of being injected into a submucosa of the bronchus/bronchiole via the puncture portion by the syringe connected to the connection portion.
Claim 42
Dependent Claim
59 words
37 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising a puncture portion capable of puncturing a mucosa of the bronchus/bronchiole at its leading end, the bronchus/bronchiole of the subject being embolized by a living tissue which proliferates about an exposed portion with the puncture portion puncturing the mucosa of the bronchus/bronchiole.
Claim 43
Dependent Claim
59 words
37 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising a puncture portion capable of puncturing a mucosa of the bronchus/bronchiole at its leading end, the bronchus/bronchiole of the subject being embolized by a living tissue which proliferates about an exposed portion with the puncture portion puncturing the mucosa of the bronchus/bronchiole.
Claim 44
Dependent Claim
66 words
38 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising a cap capable of being attached to a leading end of an endoscope having a channel through which to insert a catheter, a cap having a sheath which guides a puncture portion of the catheter from a leading opening of the channel to a through-hole opened in the cap.
Claim 45
Dependent Claim
66 words
38 . A medical device which is used for embolization of a bronchus/bronchiole of a subject, comprising a cap capable of being attached to a leading end of an endoscope having a channel through which to insert a catheter, a cap having a sheath which guides a puncture portion of the catheter from a leading opening of the channel to a through-hole opened in the cap.
Claim 46
Dependent Claim
21 words
39 . The medical device according to claim 38 , wherein the through-hole is opened in a side of the cap.
Claim 47
Dependent Claim
33 words
40 . The medical device according to claim 39 , wherein a balloon to be expanded during treatment is attached to the side opposite to the side in which the through-hole is opened.
Claim 48
Dependent Claim
71 words
41 . A method of embolizing a bronchus/bronchiole of a subject, comprising: guiding a puncture portion of an injection device to a part to be embolized in the bronchus/bronchiole of the subject; puncturing a mucosa of the bronchus/bronchiole in the part to be embolized with the puncture portion of the injection device; and injecting an injection material into a submucosa of the bronchus/bronchiole to swell an inside wall of the bronchus/bronchiole.
Claim 49
Dependent Claim
71 words
41 . A method of embolizing a bronchus/bronchiole of a subject, comprising: guiding a puncture portion of an injection device to a part to be embolized in the bronchus/bronchiole of the subject; puncturing a mucosa of the bronchus/bronchiole in the part to be embolized with the puncture portion of the injection device; and injecting an injection material into a submucosa of the bronchus/bronchiole to swell an inside wall of the bronchus/bronchiole.
Claim 50
Dependent Claim
58 words
42 . The method of embolizing a bronchus/bronchiole according to claim 41 , wherein the injection device includes a catheter having, at its leading end, a puncture portion capable of puncturing a mucosa of the bronchus/bronchiole and, at its distal end, a connection portion to which to connect a syringe, the injection material being injected by the syringe.
Claim 51
Dependent Claim
23 words
43 . The method of embolizing a bronchus/bronchiole according to claim 41 , wherein the injection material contains a fibrin adhesive or collagen.
Claim 52
Dependent Claim
37 words
44 . The method of embolizing a bronchus/bronchiole according to claim 41 , wherein the injection material is a material in which a particulate substance which is a solid component is suspended in a liquid base material.
Claim 53
Dependent Claim
30 words
45 . The method of embolizing a bronchus/bronchiole according to claim 44 , wherein the particulate substance is selected from a group consisting of silicone, metal particles, apatite and β-TCP.
Claim 54
Dependent Claim
37 words
46 . The method of embolizing a bronchus/bronchiole according to claim 41 , further comprising adding a curing agent to the injected injection material after the injecting of the injection material into the submucosa of the bronchus/bronchiole.
Claim 55
Dependent Claim
29 words
47 . The method of embolizing a bronchus/bronchiole according to claim 41 , wherein the injection material has a property to expand by absorbing water in a living body.
Claim 56
Dependent Claim
88 words
48 . The method of embolizing a bronchus/bronchiole according to claim 42 , wherein: the injection device further includes an endoscope having a channel through which to insert the catheter, and a cap capable of being attached to a leading end of the endoscope, a cap having a sheath which guides a puncture portion of the catheter from a leading opening of the channel to a through-hole opened in the cap, the method further comprising guiding the puncture portion from the opening of the channel to the through-hole.
Claim 57
Dependent Claim
53 words
49 . The method of embolizing a bronchus/bronchiole according to claim 48 , wherein: a balloon is attached to the side opposite to the side in which the through-hole is opened, the method further comprising expanding the balloon after guiding the puncture portion of the injection device to the part to be embolized.
Claim 58
Dependent Claim
61 words
50 . A method of embolizing a bronchus/bronchiole of a subject, comprising: guiding a placing object to a part to be embolized in the bronchus/bronchiole of the subject; puncturing a mucosa of the bronchus/bronchiole in the part to be embolized with the puncture portion of the placing object; and proliferating a living tissue about an exposed portion of the placing object.
Claim 59
Dependent Claim
61 words
50 . A method of embolizing a bronchus/bronchiole of a subject, comprising: guiding a placing object to a part to be embolized in the bronchus/bronchiole of the subject; puncturing a mucosa of the bronchus/bronchiole in the part to be embolized with the puncture portion of the placing object; and proliferating a living tissue about an exposed portion of the placing object.
Claim 60
Dependent Claim
40 words
51 . The method of embolizing a bronchus/bronchiole according to claim 50 , wherein the puncture portion of the placing object has a sharp leading end having a shape of a claw for preventing the placing object from coming off.
Claim 61
Dependent Claim
46 words
52 . A method of embolizing a bronchus/bronchiole of a subject, comprising: causing tissue of the bronchus/bronchiole to adhere closely to each other by changing the shape of the tissue by at least any of local injection, dissection and suturing, adhesion and formation of granulation tissue.
Claim 62
Dependent Claim
46 words
52 . A method of embolizing a bronchus/bronchiole of a subject, comprising: causing tissue of the bronchus/bronchiole to adhere closely to each other by changing the shape of the tissue by at least any of local injection, dissection and suturing, adhesion and formation of granulation tissue.
Claim 63
Dependent Claim
36 words
53 . A method of giving treatment to lung emphysema, comprising: inserting an embolization device into a pleural cavity; and embolizing the bronchus without cutting a substantial portion of a lung under a pleural cavity scope.
Claim 64
Dependent Claim
36 words
53 . A method of giving treatment to lung emphysema, comprising: inserting an embolization device into a pleural cavity; and embolizing the bronchus without cutting a substantial portion of a lung under a pleural cavity scope.
Claim 65
Dependent Claim
24 words
54 . The method of giving treatment to lung emphysema according to claim 53 , wherein a placing object is placed outside the bronchus.
Claim 66
Dependent Claim
28 words
55 . The method of giving treatment to lung emphysema according to claim 53 , wherein a placing object is placed in an internal cavity of the bronchus.
Claim 67
Dependent Claim
27 words
56 . The method of giving treatment to lung emphysema according to claim 53 , wherein a placing object is placed in a wall of the bronchus.
Claim 68
Dependent Claim
36 words
57 . A method of guiding an embolization device via a bronchus, the method comprising: confirming a part to be embolized, through a pleural cavity scope; and giving treatment to lung emphysema by embolizing the bronchus.
Claim 69
Dependent Claim
36 words
57 . A method of guiding an embolization device via a bronchus, the method comprising: confirming a part to be embolized, through a pleural cavity scope; and giving treatment to lung emphysema by embolizing the bronchus.
Claim 70
Dependent Claim
61 words
58 . A method of embolizing a bronchus/bronchiole of a subject, comprising: carrying a knife-shaped treatment element to a part to be embolized in the bronchus/bronchiole of the subject; dissecting and peeling a mucosa of the bronchus/bronchiole in the part to be embolized, by means of the treatment element; and suturing the peeled mucosa of the bronchus/bronchiole to embolize the bronchus/bronchiole.
Claim 71
Dependent Claim
61 words
58 . A method of embolizing a bronchus/bronchiole of a subject, comprising: carrying a knife-shaped treatment element to a part to be embolized in the bronchus/bronchiole of the subject; dissecting and peeling a mucosa of the bronchus/bronchiole in the part to be embolized, by means of the treatment element; and suturing the peeled mucosa of the bronchus/bronchiole to embolize the bronchus/bronchiole.
Claim 72
Dependent Claim
53 words
59 . A method of embolizing a bronchus/bronchiole of a subject, comprising: carrying a spraying device to a part to be embolized in the bronchus/bronchiole of the subject; and spraying a spray material having a property to cause inflammation in tissue in the part to be embolized, by means of the spraying device.
Claim 73
Dependent Claim
53 words
59 . A method of embolizing a bronchus/bronchiole of a subject, comprising: carrying a spraying device to a part to be embolized in the bronchus/bronchiole of the subject; and spraying a spray material having a property to cause inflammation in tissue in the part to be embolized, by means of the spraying device.
Claim 74
Dependent Claim
44 words
60 . The method of embolizing a bronchus/bronchiole of a subject according to claim 59 , further comprising expanding a balloon provided behind an ejection port of the spraying device, after the step of guiding the spraying device to the part to be embolized.
Claim 75
Dependent Claim
47 words
61 . The method of embolizing a bronchus/bronchiole of a subject according to claim 59 , further comprising, after spraying the spray material, placing an embolization element on a central side of a part sprayed with the spray material, and preventing the spray material from flowing backward.
Claim 76
Dependent Claim
30 words
62 . The method of embolizing a bronchus/bronchiole of a subject according to claim 61 , further comprising the step of retrieving the embolization element after placing the placing object.
Claim 77
Dependent Claim
45 words
63 . A method of embolizing a bronchus/bronchiole of a subject, comprising: inserting a trocar into a chest of the subject; inserting a treatment element through the trocar; selecting the bronchus/bronchiole by means of the inserted treatment element; and binding the selected bronchus/bronchiole from outside.
Claim 78
Dependent Claim
45 words
63 . A method of embolizing a bronchus/bronchiole of a subject, comprising: inserting a trocar into a chest of the subject; inserting a treatment element through the trocar; selecting the bronchus/bronchiole by means of the inserted treatment element; and binding the selected bronchus/bronchiole from outside.
Claim 79
Dependent Claim
49 words
64 . A method of embolizing a bronchus/bronchiole of a subject, comprising: inserting a trocar into a chest of the subject; inserting a treatment element through the trocar; selecting the bronchus/bronchiole by means of the inserted treatment element; and injecting an embolization material into the selected bronchus/bronchiole from outside.
Claim 80
Dependent Claim
49 words
64 . A method of embolizing a bronchus/bronchiole of a subject, comprising: inserting a trocar into a chest of the subject; inserting a treatment element through the trocar; selecting the bronchus/bronchiole by means of the inserted treatment element; and injecting an embolization material into the selected bronchus/bronchiole from outside.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.