US20030018327A1
Expired / Lapsed
US
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Systems and techniques for lung volume reduction
Assignee: Individual
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Filing: 2002-07-18
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Granted: —
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Expires: 2022-07-18
Abstract
Abstract This invention provides least invasive instruments and methods for lung volume reduction. In one embodiment, a catheter has a collapsible working end electrode that can engage an artery wall in a plurality of locations in a patient's bronchial tree to deliver Rf energy to the vessel wall. The application of energy induces the vessel wall to shrink and occlude. The occlusion of the vessel will cause the tertiary bronchus to shrink and wither until cell death is caused wherein the tissue then will be resorbed by the patient's body.
Inventors
- 👤 Csaba Truckai
- 👤 John Shadduck
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 22:08
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B2018/00053; A61B2018/00107; A61B2018/00148; A61B2018/00214; A61B2018/0022; A61B2018/00315; A61B2018/00541; A61B2018/00636; A61B2018/00773; A61B2018/00845; A61B2018/00851; A61B18/1206; A61B2018/1246; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1407; A61B2018/141; A61B2018/1435; A61B2018/1465; A61B2218/00; A61B2218/001; A61B2218/002
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
114 words
1 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) applying energy to the artery wall at the targeted site by means of electrical current flow from at least one electrode carried at said working end to the artery wall, wherein the application of energy damages and occludes the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes subsequently causes resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 2
Dependent Claim
114 words
1 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) applying energy to the artery wall at the targeted site by means of electrical current flow from at least one electrode carried at said working end to the artery wall, wherein the application of energy damages and occludes the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes subsequently causes resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 3
Dependent Claim
26 words
2 . The method of claim 1 wherein current flow in step (b) is provided by said at least one electrode functioning with a single polarity.
Claim 4
Dependent Claim
26 words
3 . The method of claim 1 wherein current flow in step (b) is provided between first and second spaced apart electrodes functioning with opposing polarities.
Claim 5
Dependent Claim
40 words
4 . The method of claim 1 wherein said at least one electrode has a collapsed position and an expanded position and step (a) includes the step of moving the electrode to the expanded position to engage the arterial wall.
Claim 6
Dependent Claim
30 words
5 . The method of claim 1 wherein step (b) includes the step of moving said at least one electrode along the arterial wall while delivering electrical current flow thereto.
Claim 7
Dependent Claim
41 words
6 . The method of claim 1 wherein said at least one electrode is carried on an expandable balloon and step (a) includes the step of expanding the balloon to move said at least one electrode to engage the arterial wall.
Claim 8
Dependent Claim
71 words
7 . The method of claim 6 wherein spaced apart bi-polar electrodes are carried on an expandable balloon and step (a) includes the step of expanding the balloon to thereby engage the arterial wall wherein the degree of expansion of elastic portions of the balloon wall intermediate said bi-polar electrodes controls the center-to-center dimension between said bi-polar electrodes and thereby controls the depth of energy delivery in the engaged arterial wall.
Claim 9
Dependent Claim
91 words
8 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying an occlusive device from said working end into the lumen of the artery to occlude the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 10
Dependent Claim
91 words
8 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying an occlusive device from said working end into the lumen of the artery to occlude the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 11
Dependent Claim
19 words
9 . The method of claim 8 wherein step (b) deploys a self-expanding body of a shape memory material.
Claim 12
Dependent Claim
14 words
10 . The method of claim 9 wherein the self-expanding body is of nitinol.
Claim 13
Dependent Claim
91 words
11 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying a biocompatible glue from said working end into the lumen of the artery to occlude the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes later resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 14
Dependent Claim
91 words
11 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying a biocompatible glue from said working end into the lumen of the artery to occlude the artery at said targeted site; and (c) withdrawing the catheter working end from the patient's vasculature wherein the occluded artery causes later resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 15
Dependent Claim
13 words
12 . The method of claim 11 wherein the biocompatible glue is cyanoacrylate.
Claim 16
Dependent Claim
104 words
13 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying a volume of a desiccated hydrogel into the artery from the catheter working end; (c) wherein hydration and expansion of the hydrogel volume engages the artery walls to occlude the artery at said targeted site; and (d) withdrawing the catheter working end from the patient's vasculature wherein the occlusion causes subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 17
Dependent Claim
104 words
13 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing a catheter working end endovascularly to at least one targeted site in a bronchial artery; (b) deploying a volume of a desiccated hydrogel into the artery from the catheter working end; (c) wherein hydration and expansion of the hydrogel volume engages the artery walls to occlude the artery at said targeted site; and (d) withdrawing the catheter working end from the patient's vasculature wherein the occlusion causes subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 18
Dependent Claim
12 words
14 . The method of claim 13 wherein the hydrogel is bioabsorbable.
Claim 19
Dependent Claim
16 words
15 . The method of claim 13 wherein the hydrogel is a microporous or superporous gel.
Claim 20
Dependent Claim
108 words
16 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing an elongate member through airway in a patient's bronchus to at least one targeted site; (b) applying energy to said targeted site by delivering electrical current flow at a selected power level to at least one electrode carried at said working end, wherein the application of energy damages and occludes blood vessels in the bronchial wall at said targeted site; and (c) withdrawing the member wherein the occluded blood vessels cause subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 21
Dependent Claim
108 words
16 . A method for treating advanced chronic obstructive lung disease by reducing lung volume, comprising the steps of: (a) introducing an elongate member through airway in a patient's bronchus to at least one targeted site; (b) applying energy to said targeted site by delivering electrical current flow at a selected power level to at least one electrode carried at said working end, wherein the application of energy damages and occludes blood vessels in the bronchial wall at said targeted site; and (c) withdrawing the member wherein the occluded blood vessels cause subsequent resorption of portions of the bronchus distal to said targeted site thereby reducing lung volume.
Claim 22
Dependent Claim
121 words
17 . An endovascular catheter system for treating advanced chronic obstructive lung disease by reducing lung volume, comprising: an elongate flexible catheter sleeve extending along an axis from a proximal handle portion to a working end; an expandable balloon member carried at the working end; first and second spaced apart thin-film conductor portions carried on a surface of the expandable balloon; wherein said first and second conductor portions are operatively coupled to an electrical source defining opposing polarities therein for delivering energy to body structure engaged by said conductor portions; and wherein said first and second conductor portions are substantially non-elastic portions of the balloon wall with elastic portions of the balloon wall being intermediate said first and second conductor portions.
Claim 23
Dependent Claim
121 words
17 . An endovascular catheter system for treating advanced chronic obstructive lung disease by reducing lung volume, comprising: an elongate flexible catheter sleeve extending along an axis from a proximal handle portion to a working end; an expandable balloon member carried at the working end; first and second spaced apart thin-film conductor portions carried on a surface of the expandable balloon; wherein said first and second conductor portions are operatively coupled to an electrical source defining opposing polarities therein for delivering energy to body structure engaged by said conductor portions; and wherein said first and second conductor portions are substantially non-elastic portions of the balloon wall with elastic portions of the balloon wall being intermediate said first and second conductor portions.
Claim 24
Dependent Claim
22 words
18 . The endovascular catheter system of claim 17 wherein said first and second conductor portions comprise a plurality of axially-extending elements.
Claim 25
Dependent Claim
22 words
19 . The endovascular catheter system of claim 17 wherein said first and second conductor portions comprise a plurality of helically-extending elements.
Claim 26
Dependent Claim
22 words
20 . The endovascular catheter system of claim 17 wherein said first and second conductor portions comprise a plurality of circumferentially-extending elements.
References Cited (Backward Citations)
No citation records indexed.
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