US20020044907A1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Catheter systems and methods for their use in the treatment of calcified vascular occlusions
Assignee: Cordis US Corp
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Filing: 1999-08-27
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Granted: —
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Expires: 2019-08-27
Abstract
Abstract Catheter systems and methods for their use in enhancing fluid flow through a vascular site occupied by a vascular occlusion are provided. The subject catheter systems include at least an aspiration catheter and at least one of a total occlusion insert catheter and a partial occlusion insert catheter, where the insert catheters are capable of being slidably moved in the lumen of the aspiration catheter. In practicing the subject methods, a surface of the vascular occlusion is flushed with an acidic dissolution fluid using the subject catheter systems for a period of time sufficient for fluid flow through the vascular site to be enhanced, e.g. increased or established. The subject catheter systems and methods find use in the treatment of a variety of different vascular diseases characterized by the presence of calcified vascular occlusions, including peripheral and coronary vascular diseases.
Inventors
- 👤 Brent R. Constantz
- 👤 Peter K. Johansson
- 👤 Erin McGurk
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:17
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1011; A61M29/00; A61M29/02; A61M2025/0004; A61M2025/1043; A61M2025/1052; A61M2025/1095; A61M25/0021; A61M25/0023; A61M25/0026
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
123 words
1 . A catheter system comprising: (a) an aspiration catheter comprising an elongated tube having an aspiration lumen ending in an open distal end and an inflatable balloon at said distal end; and (b) at least one of: (i) a total occlusion catheter insert comprising an elongated tube having an open distal end; and (ii) a partial occlusion catheter insert comprising an elongated tube having a sealed distal end, an inflatable balloon at said distal end and at least one infusion port proximal to said inflatable balloon wherein said total and partial occlusion catheter inserts are capable of being slidably positioned within said aspiration catheter to produce an annular space at the distal end of said aspiration catheter through which fluid may flow.
Claim 2
Dependent Claim
123 words
1 . A catheter system comprising: (a) an aspiration catheter comprising an elongated tube having an aspiration lumen ending in an open distal end and an inflatable balloon at said distal end; and (b) at least one of: (i) a total occlusion catheter insert comprising an elongated tube having an open distal end; and (ii) a partial occlusion catheter insert comprising an elongated tube having a sealed distal end, an inflatable balloon at said distal end and at least one infusion port proximal to said inflatable balloon wherein said total and partial occlusion catheter inserts are capable of being slidably positioned within said aspiration catheter to produce an annular space at the distal end of said aspiration catheter through which fluid may flow.
Claim 3
Dependent Claim
22 words
2 . The catheter system according to claim 1 , wherein said system comprises both said partial and total occlusion catheter insert.
Claim 4
Dependent Claim
24 words
3 . The catheter system according to claim 1 , wherein said aspiration catheter further comprises a guidewire lumen separate from said aspiration lumen.
Claim 5
Dependent Claim
119 words
4 . A coaxial catheter assembly comprising: (a) an aspiration catheter comprising an elongated tube having an aspiration lumen ending in an open distal end and an inflatable balloon at said distal end; and (b) one of: (i) a total occlusion catheter insert comprising an elongated tube having an open distal end; or (ii) a partial occlusion catheter insert comprising an elongated tube having a sealed distal end, an inflatable balloon at said distal end and at least one infusion port proximal to said inflatable balloon slidably positioned within said aspiration lumen of said aspiration catheter in a manner such that an annular space through which fluid may flow is present at the distal end of said aspiration catheter.
Claim 6
Dependent Claim
119 words
4 . A coaxial catheter assembly comprising: (a) an aspiration catheter comprising an elongated tube having an aspiration lumen ending in an open distal end and an inflatable balloon at said distal end; and (b) one of: (i) a total occlusion catheter insert comprising an elongated tube having an open distal end; or (ii) a partial occlusion catheter insert comprising an elongated tube having a sealed distal end, an inflatable balloon at said distal end and at least one infusion port proximal to said inflatable balloon slidably positioned within said aspiration lumen of said aspiration catheter in a manner such that an annular space through which fluid may flow is present at the distal end of said aspiration catheter.
Claim 7
Dependent Claim
24 words
5 . The coaxial catheter assembly according to claim 4 , wherein said total occlusion catheter insert is slidably positioned within said aspiration lumen.
Claim 8
Dependent Claim
23 words
6 . The coaxial catheter assembly according to claim 4 , wherein said partial occlusion catheter is slidably positioned within said aspiration lumen.
Claim 9
Dependent Claim
57 words
7 . A method of enhancing fluid flow through a vascular site occupied by a vascular occlusion, said method comprising: flushing a surface of said vascular occlusion with an acidic dissolution fluid for a period of time sufficient for fluid flow to be enhanced through said vascular site; whereby fluid flow is established through said vascular site.
Claim 10
Dependent Claim
57 words
7 . A method of enhancing fluid flow through a vascular site occupied by a vascular occlusion, said method comprising: flushing a surface of said vascular occlusion with an acidic dissolution fluid for a period of time sufficient for fluid flow to be enhanced through said vascular site; whereby fluid flow is established through said vascular site.
Claim 11
Dependent Claim
15 words
8 . The method according to claim 7 , wherein said vascular occlusion comprises calcium.
Claim 12
Dependent Claim
16 words
9 . The method according to claim 7 , wherein said occlusion is a total occlusion.
Claim 13
Dependent Claim
16 words
10 . The method according to claim 7 , wherein said occlusion is a partial occlusion.
Claim 14
Dependent Claim
28 words
11 . The method according to claim 7 , wherein a coaxial catheter assembly according to claim 4 is used to flush said surface of said vascular occlusion.
Claim 15
Dependent Claim
22 words
12 . The method according to claim 11 , wherein said coaxial catheter assembly is the assembly according to claim 5 .
Claim 16
Dependent Claim
22 words
13 . The method according to claim 11 , wherein said coaxial catheter assembly is the assembly according to claim 6 .
Claim 17
Dependent Claim
34 words
14 . A method of flushing a vascular site with a solution, said method comprising: introducing and removing said solution from said vascular site with a coaxial catheter assembly according to claim 4 .
Claim 18
Dependent Claim
22 words
15 . The method according to claim 14 , wherein said coaxial catheter assembly is the assembly according to claim 5 .
Claim 19
Dependent Claim
22 words
16 . The method according to claim 14 , wherein said coaxial catheter assembly is the assembly according to claim 6 .
Claim 20
Dependent Claim
69 words
17 . A system for enhancing fluid flow through a vascular site occupied by a vascular occlusion, said system comprising: (a) a coaxial catheter assembly according to claim 4 ; (b) a manifold; (c) an acidic fluid dissolution reservoir in fluid communication the insert catheter of said coaxial catheter assembly; and (d) a source of negative pressure in fluid communication with said aspiration lumen of said coaxial catheter assembly.
Claim 21
Dependent Claim
18 words
18 . The system according to claim 17 , wherein said system further includes a balloon inflation means.
Claim 22
Dependent Claim
17 words
19 . The system according to claim 18 , wherein said balloon inflation means is a syringe.
Claim 23
Dependent Claim
16 words
20 . The system according to claim 17 , wherein said system further comprises a guidewire.
Claim 24
Dependent Claim
30 words
21 . A kit for use in enhancing fluid flow through a vascular site occupied by a vascular occlusion, said kit comprising: a catheter system according to claim 1 .
Claim 25
Dependent Claim
16 words
22 . The kit according to claim 21 , wherein said kit further comprises a guidewire.
Claim 26
Dependent Claim
17 words
23 . The kit according to claim 21 , wherein said kit further comprises an imaging agent.
Claim 27
Dependent Claim
18 words
24 . The kit according to claim 21 , wherein said kit further comprises an acidic dissolution solution.
Claim 28
Dependent Claim
39 words
25 . A kit for use in enhancing fluid flow through a vascular site occupied by a vascular occlusion, said kit comprising: (a) a catheter system according to claim 1; (b) an acidic dissolution solution; and (c) a guidewire.
Claim 29
Dependent Claim
17 words
26 . The kit according to claim 25 , wherein said kit further comprises a washing solution.
Claim 30
Dependent Claim
17 words
27 . The kit according to claim 25 , wherein said kit further comprises a surfactant solution.
Claim 31
Dependent Claim
17 words
28 . The kit according to claim 25 , wherein said kit further comprises an imaging agent.
Claim 32
Dependent Claim
23 words
29 . An acidic dissolution fluid consisting essentially of: hydrogen chloride in a concentration ranging from about 0.01 to 1.0 N; and water.
Claim 33
Dependent Claim
23 words
29 . An acidic dissolution fluid consisting essentially of: hydrogen chloride in a concentration ranging from about 0.01 to 1.0 N; and water.
Claim 34
Dependent Claim
17 words
30 . The solution according to claim 29 , wherein said solution further consists of a salt.
Claim 35
Dependent Claim
14 words
31 . The solution according to claim 30 , wherein said salt is NaCl.
Claim 36
Dependent Claim
24 words
32 . The solution according to claim 31 , wherein said NaCl is present in a concentration ranging from about 0.01 to 0.1 M.
References Cited (Backward Citations)
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