Plaster for patch

Abstract

Abstract PURPOSE: To obtain the titled plaster having excellent hydrophilic nature, water retention, adhesivity to the skin and durability of cold feeling, exerting no bad influence on the skin, containing a reaction product of an amino group- containing polysaccharide and a hydrophilic polyfunctional crosslinking agent capable of reacting the amino group. CONSTITUTION: Plaster for patch containing a reaction product of an amino group-containing polysaccharide (especially preferably chitosan, deacetylated product of chitin) selected from deacetylated products of chitin, colominic acid, keratosulfate, chondroitin and hyaluronic acid and desulfated product of heparin acid and a hydrophilic polyfunctional crosslinking agent capable of reacting the amino group, such as an N-hydroxyimide ester compound shown by formula I (X is residue of 2W6C compound containing 2W5 hydroxyl groups; A is oxyethylene, oxypropylene or oxybutylene; Y is dibasic acid residue; Z is group shown by formula IIWformula IV, CH=CH or CH 2 -CH 2 ; m is 1W3,000; n is 2W6). COPYRIGHT: (C)1989,JPO&Japio

Inventors

• 👤 Masami Maekawa
• 👤 Hiroshi Doi

Bibliographic Details