Process for the Manufacture of Tubular and Flat Prostheses from Animal Tissue.

Abstract

Abstract 1,195,992. Surgical implants. B. BRAUN INTERNATIONAL G.m.b.H. 8 Aug., 1967 [22 Aug., 1966], No. 36378/67. Heading A5R. [Also in Divisions B5 and F2] A prosthetic implant, such as a tube or a patch of tissue, is sterile and comprises three or more layers of animal tissue (e.g. submucosa or serosa from animal intestines) united together, for example, by a collagen paste or by treatment with lactic acid. In particular, a tubular implant is formed 'by covering a tubular former with a tube of the animal tissue, coating the tissue with collagen paste, and then applying a second tube of the animal tissue. The tubular former is of a plastics or glaca material and is smooth surfaced or is formed with a screw-thread so that by temporarily winding a filament over each layer of tissue into the thread the implant is crimped. To facilitate removing the former from within the implant, the former may be heated and stretched so that it can be ramoved from the implant as a filament (Figure 2, not shown). Exemplified therapeutic substances may be added to the collagen paste and the tubular implant may be reinforced by synthetic material or by a metalic spiral and may vary in diameter conically along its length. The animal tissue may be bleached with hydrogen peroxide before being used to form the implant and the implant, or each of its layers in turn, may be hardened with an aldehyde.

Inventors

No inventors recorded.

Bibliographic Details