EP0754017B1
Expired / Lapsed
EP
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Stent with collagen
Assignee: Boston Scientific Scimed Inc
•
Filing: 1995-04-26
•
Granted: 2002-06-19
•
Expires: 2015-04-26
Abstract
Abstract Collagen applied to a vascular stent for increasing the biocompatibility of the stent on implantation and method of treatment
Inventors
- 👤 Andrew W. Buirge
- 👤 Paul J. Buscemi
- 👤 Paul H. Burmeister
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 13:31
CPC Classifications
A; A61; A61M; A61M29/00; A61M29/02; A61F; A61F2/00; A61F2/0004; A61F2/0022; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/915; A61F2/95; A61F2/958; A61L; A61L31/00; A61L31/08; A61L31/10; A61F2/88; A61F2/885; A61F2/89; A61F2002/072; A61F2002/075; A61F2002/828; A61F2002/91533; A61F2002/91541; A61F2002/9155; A61F2002/91558; A61F2002/9583; A61F2210/00; A61F2210/0076; A61F2220/00; A61F2220/0025; A61F2220/005; A61F2220/0058; A61F2220/0075; A61F2220/0091; A61F2250/00; A61F2250/0058; A61F2250/0067; A61M25/00; A61M25/0043; A61M25/0045; Y; Y10; Y10S; Y10S623/00; Y10S623/915; Y10S623/916; Y10S623/917
Claims Analysis
Total Claims: 37
Claim 1
Independent Claim
125 words
A vascular prosthesis comprised of a support framework (10,40,50,60,120,140) and a
collagen material (12,110) overlying at least a portion of a surface thereof, with the collagen material
being selected from supported and unsupported bovine or porcine collagen, laminin, keratin,
glycosaminoglycans, proteoglycans, pure carbohydrates, fibrin, fibronectin, albumin,
globulins, and other bloodborne proteins, hyaluronic acid or the like, combinations thereof
and any natural materials that form membranes with collagen, the support framework
comprising an expandable stent having a collapsed cylindrical position and an expanded
cylindrical position, wherein the collagen material is in sheet form and is oriented with
respect to the longitudinal dimension of the stent such that the stretch properties of the
collagen are at an angle with respect to the longitudinal dimension of the stent.
Claim 2
Dependent Claim
14 words
The prosthesis of claim 1 wherein the framework is a stent of variable
diameter.
Claim 3
Dependent Claim
18 words
The prosthesis according to any one of the previous claims wherein the stent
is of the self-expanding type.
Claim 4
Dependent Claim
19 words
The prosthesis according to any one of the previous claims wherein the stent
is coated with a collagen material.
Claim 5
Dependent Claim
19 words
The prosthesis according to any one of claims 1 to 3 wherein the stent
is embedded in collagen material.
Claim 6
Dependent Claim
27 words
The prosthesis according to any one of claims 1 to 3 wherein the stent
is comprised of an open framework including a collagen coating over the framework.
Claim 7
Dependent Claim
25 words
The prosthesis according to any one of claims 1 to 3 wherein the
framework is comprised of a network of interconnecting struts coated with collagen.
Claim 8
Dependent Claim
26 words
The prosthesis according to any one of claims 1 to 3 wherein the
framework is comprised of a wire network, the wire being coated with collagen.
Claim 9
Dependent Claim
40 words
The prosthesis according to any one of claims 1 to 3 wherein the stent
is comprised of a generally cylindrical body coated with a collagen material and the
collagen material is in the form of a sleeve overlying the stent.
Claim 10
Dependent Claim
24 words
The prosthesis of claim 9 wherein the collagen coating is Type IV and/or
Type I and the collagen sleeve is comprised of Type IV.
Claim 11
Dependent Claim
32 words
The prosthesis according to any one of the previous claims wherein the
collagen material forms a layer, the layer of collagen material being substantially the same
length and substantially overlapping the stent.
Claim 12
Dependent Claim
26 words
The prosthesis according to any one of claims 1 to 8 in which the
collagen material is in the form of a sleeve overlying the stent.
Claim 13
Dependent Claim
21 words
The prosthesis according to any one of claims 1 to 8 wherein the
collagen material covers the stent inside and out.
Claim 14
Dependent Claim
27 words
The prosthesis according to any one of claims 1 to 8 wherein the
collagen material is in the form of an outer sleeve and an inner sleeve.
Claim 15
Dependent Claim
20 words
The prosthesis according to any one of the previous claims wherein the
collagen material is comprised of collagen per se.
Claim 16
Dependent Claim
21 words
The prosthesis according to any one of the previous claims wherein the
collagen material is comprised of collagen on a support.
Claim 17
Dependent Claim
11 words
The prosthesis of claim 16 wherein the support is a fabric.
Claim 18
Dependent Claim
19 words
The prosthesis according to any one of claims 9, 10, 12 or 14, wherein the
sleeve has elastic properties.
Claim 19
Dependent Claim
29 words
The prosthesis according to any one of claims 9, 10, 12, 14 or 18, wherein
the sleeve is sized large with respect to the framework at least before implantation.
Claim 20
Dependent Claim
22 words
The prosthesis according to any one of claims 1-8, wherein the
collagen material is in the form of an inner luminal liner.
Claim 21
Dependent Claim
14 words
The prosthesis according to claim 20 wherein the collagen
material comprises a bilayer arrangement.
Claim 22
Dependent Claim
18 words
The prosthesis according to claim 21 wherein one of the layers in the bilayer
is a polymeric material.
Claim 23
Dependent Claim
26 words
The prosthesis according to any one of claims 20 to 22 wherein the liner has
cuffs at either end which overlap the ends of the stent.
Claim 24
Dependent Claim
22 words
The prosthesis according to any one of claims 20 to 23 wherein the stent has
wall openings and the liner is perforated.
Claim 25
Dependent Claim
14 words
The prosthesis of claim 24 wherein the perforations are about 10-60 microns
in diameter.
Claim 26
Dependent Claim
25 words
The prosthesis according to any one of claims 21 to 25 wherein the bilayer
liner is comprised of at least two types of collagen material.
Claim 27
Dependent Claim
22 words
The prosthesis according to any one of claims 21 to 26 wherein the collagen
material includes Type I and Type IV layers.
Claim 28
Dependent Claim
21 words
The prosthesis of claim 27, wherein the Type IV is the innermost layer and
the Type I layer includes a drug.
Claim 29
Dependent Claim
32 words
The prosthesis according to any one of claims 1 to 8 wherein the collagen material is a
multi-layer arrangement of Type I and Type IV collagen on the outside of the stent.
Claim 30
Dependent Claim
13 words
The prosthesis of claim 29 wherein the Type IV is the outermost layer.
Claim 31
Dependent Claim
17 words
The prosthesis according to any one of claims 10 and 27-30 wherein the Type
IV is SIS.
Claim 32
Dependent Claim
23 words
The prosthesis according to any one of claims 1 to 8 wherein the
collagen material includes SIS on the outside of the stent.
Claim 33
Dependent Claim
32 words
The prosthesis according to any one of claims 1 to 8 wherein the collagen material is in the form of an inner
and outer layer of SIS collagen positioned on the stent.
Claim 34
Dependent Claim
33 words
The prosthesis according to any one of claims 1 to 3 wherein the
support framework is coated with a collagen material and the collagen material is in the form of a sleeve
thereover.
Claim 35
Dependent Claim
19 words
The prosthesis of claim 34 wherein the sleeve is SIS and the coating is Type
I or Type IV.
Claim 36
Dependent Claim
16 words
The prosthesis according to any one of the previous claims wherein the
collagen includes added agent.
Claim 37
Dependent Claim
10 words
The prosthesis of claim 36 wherein the agent is heparin.
References Cited (Backward Citations)
EP0461791A1
Cited
US5147370A
Cited
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