Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
202 words
A fluid, injectable, bioabsorbable microdispersion suitable for use as a soft tissue repair or augmentation material in animals comprising a fluid carrier that is a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and liquid polymers of a plurality of first lactone and second lactone repeating units; wherein the first lactone repeating units are selected from the group consisting of ε-caprolactone repeating units, trimethylene carbonate repeating units, ether lactone repeating units and combinations thereof and the second lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units, p-dioxanone repeating units and combinations thereof; and a particulate material that is selected from the group consisting of solid homopolymers of poly(ε-caprolactone), solid homopolymers of poly(p-dioxanone), solid homopolymers of poly(trimethylene carbonate), solid copolymers of a plurality of e-caprolactone repeating units and third lactone repeating units, solid copolymers of a plurality of trimethylene carbonate repeating units and second lactone repeating units; wherein the third lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units, trimethylene carbonate repeating units, p-dioxanone repeating units, 1,4-dioxepan-2-one repeating units, 1-5-dioxepan-2-one repeating units and combinations thereof.
Claim 2
Dependent Claim
122 words
The fluid, injectable, bioabsorbable microdispersion of claim 1 wherein the fluid carrier is a noncrystalline liquid polymer with an inherent viscosity of from 0.05 dL/g to 0.5 dL/g selected from the group consisting of polymers of from 65 mole percent to 35 mole percent of ε-caprolactone repeating units with the remainder being the third lactone repeating units, polymers of from 65 to 35 mole percent of ether lactone repeating units with the remainder being the second lactone repeating units, polymers of from 65 to 35 mole percent of trimethylene carbonate repeating units with the remainder being the second lactone repeating units and polymers of from 65 to 35 mole percent ether lactone repeating units with the remainder being trimethylene carbonate repeating units.
Claim 3
Dependent Claim
44 words
The fluid, injectable, bioabsorbable microdispesion of claim 1 or claim 2 wherein the particulate material is a solid polymer of ε-caprolactone repeating units and the third lactone repeating units and contains from 100 to 70, preferably 95 to 85, mole percent ε-caprolactone repeating units.
Claim 4
Dependent Claim
42 words
The fluid, injectable, bioabsorbable microdispersion of claim 1 or claim 2 wherein the particulate material is a solid polymer of trimethylene carbonate repeating units and the second lactone repeating units and contains from 1 to 20 mole percent trimethylene carbonate repeating units.
Claim 5
Dependent Claim
31 words
The fluid, injectable, bioabsorbable microdispersion of claim 1 or claim 2 wherein the particulate material is a solid polymer selected from the group consisting of poly(ε-caprolactone), poly(ε-caprolactone-co-trimethylene carbonate, poly(ε-caprolactone-co-lactide) and poly(ε-caprolactone-co-p-dioxanone).
Claim 6
Dependent Claim
42 words
The fluid, injectable, bioabsorbable microdispersion of any one of claims 1 to 5 wherein the weight percent of the fluid carrier in the microdispersion is in the range of from 20 to 99 weight percent with the remainder being the particulate material.
Claim 7
Dependent Claim
21 words
The fluid, injectable, bioabsorbable microdispersion of any one of claims 1 to 6 wherein additionally present is a pharmaceutically active compound.
Claim 8
Dependent Claim
61 words
A preloaded pharmaceutical container having a cylindrical storage area, an outlet and an end to said cylindrical storage area wherein: the outlet has a removable sterile seal; the end has a movable sterile seal which may be advanced into said cylindrical storage area; and the cylindrical storage area contains the fluid injectable, bioabsorbable microdispersion any one of claims 1 to 7.
Claim 9
Dependent Claim
57 words
A pharmaceutical kit comprising a device containing the fluid, injectable, bioabsorbable microdispersion of any one of claims 1 to 7, wherein the device has an outlet for said microdispersion, an ejector for expelling the microdispersion through the outlet and a hollow tubular member fitted to the outlet for administering the microdispersion into a site within a body.
Claim 10
Dependent Claim
27 words
The fluid, injectable, bioabsorbable microdispersion of any one of claims 1 to 7 for use in repairing or augmenting soft tissue, in particular sphincter muscle, in animals.