EP0504881A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
Assignee: Individual
•
Filing: 1992-03-19
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Granted: —
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Expires: 2012-03-19
Abstract
Abstract A booster comprising a plenty of microbubbles of a gas in a liquid, e.g. about 4 x 10⁷ cells/ml of microbubbles of a gas having a diameter of 0.1 to 100 µm in a 3 to 5 % human serum albumin solution, and a pharmaceutical liquid composition comprising the booster as set forth above and a medicament, which are useful for the therapy of various diseases together with exposure of ultrasonic, where the therapeutic effects of the medicament is enhanced by the application of ultrasound in the presence of the booster.
Inventors
- 👤 Katsuro Tachibana
- 👤 Sunro Tachibana
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 07:44
CPC Classifications
A; A61; A61K; A61K41/00; A61K41/0028; A61K41/0004; A61K41/0047; A61K49/00; A61K49/22; A61K49/222; A61K49/223; A61K9/00; A61K9/0002; A61K9/0009; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5052
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
32 words
A booster for enhancing effects of ultrasound in the therapy of diseases, which comprises a plenty of microbubbles of a gas having a diameter of 0.1 to 100 µm in a liquid.
Claim 2
Dependent Claim
19 words
The booster according to claim 1, wherein the microbubbles are formed from air or oxygen gas in the liquid.
Claim 3
Dependent Claim
19 words
The booster according to claim 1, wherein the liquid is a 3 to 5 % human serum albumin solution.
Claim 4
Dependent Claim
36 words
A pharmaceutical liquid composition for the therapy of diseases with application of ultrasound, which comprises a plenty of microbubbles of a gas having a diameter of 0.1 to 100 µm and a medicament in a liquid.
Claim 5
Dependent Claim
19 words
The composition according to claim 4, wherein the microbubbles are formed from air or oxygen gas in the liquid.
Claim 6
Dependent Claim
19 words
The composition according to claim 4, wherein the liquid is a 3 to 5 % human serum albumin solution.
Claim 7
Dependent Claim
21 words
The composition according to claim 4, wherein the medicament is a member selected from thromobolytic agents, hormones, antibiotics, and antineoplastic agents.
Claim 8
Dependent Claim
30 words
Use of a pharmaceutical liquid composition as set forth in claim 4 for enhancing the therapeutic effect of a medicament when said pharmaceutical liquid composition is administered while applying ultrasound.
Claim 9
Dependent Claim
35 words
Use according to claim 8 , wherein the liquid composition comprises about 4 x 10⁷ cells/ml of microbubbles of a gas having a diameter of 0.1 to 100 µm and a medicament in the liquid.
Claim 10
Dependent Claim
18 words
Use according to claim 9, wherein the liquid is a 3 to 5 % human serum albumin solution.
Claim 11
Dependent Claim
36 words
Use of a pharmaceutical liquid composition comprising a plenty of microbubbles of a gas having a diameter of 0.1 to 100 µm and a medicament in a liquid in the therapy of diseases by applying ultrasound.
Claim 12
Dependent Claim
19 words
The use according to claim 11, wherein the microbubbles are formed from air or oxygen gas in the liquid.
Claim 13
Dependent Claim
19 words
The use according to claim 11, wherein the liquid is a 3 to 5 % human serum albumin solution.
References Cited (Backward Citations)
No citation records indexed.
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