EP0466505A2
Expired / Lapsed
EP
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Artificial antibody
Assignee: Takara Shuzo Co Ltd
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Filing: 1991-07-12
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Granted: —
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Expires: 2011-07-12
Abstract
Abstract An artificial antibody having antigen binding and artificial cell adhesive activity is described, comprising the amino acid sequence Arg-Gly-Asp-Ser introduced into a constant region of the H-chain of an artificial antibody. DNA coding for the artificial antibodies of the invention form another aspect of the invention.
Inventors
- 👤 Hashino Kimikazu
- 👤 Kimizuka Fusao
- 👤 Kato Ikunoshin
- 👤 Kurosawa Yoshikazu
- 👤 Titani Koiti
- 👤 Sekiguchi Kiyotoshi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 06:46
CPC Classifications
C; C07; C07K; C07K16/00; A; A61; A61P; A61P37/00; A61K; A61K38/00; C07K2317/00; C07K2317/70; C07K2317/77
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
14 words
An artificial antibody having an antigen binding activity and an artificial cell adhesive activity.
Claim 2
Dependent Claim
31 words
An artificial antibody according to claim 1 in which the artificial cell adhesive activity is caused by an amino acid sequence having a cell adhesive activity introduced into the antibody molecule.
Claim 3
Dependent Claim
28 words
An artificial antibody according to claim 1 or 2 in which the amino acid sequence is Arg-Gly-Asp-Ser (RGDS; sequence of SEQ ID No. 1 in the Sequence Listing).
Claim 4
Dependent Claim
21 words
An artificial antibody according to claim 2 or 3 in which the sequence is introduced into a constant region of H-chain.
Claim 5
Dependent Claim
30 words
A DNA which codes for a constant region of H-chain of an artificial antibody, the constant region having introduced therein an amino acid sequence having an artificial cell adhesive activity.
Claim 6
Dependent Claim
26 words
A DNA according to claim 5 in which the amino acid sequence is Arg-Gly-Asp-Ser sequence (RGDS; sequence of SEQ ID No. 1 in the Sequence Listing).
Claim 7
Dependent Claim
18 words
A DNA according to claim 5 having a sequence of SEQ ID No. 4 in the Sequence Listing.
References Cited (Backward Citations)
No citation records indexed.
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