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EP0409810A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

A method of preparing an implant body for implantation

Assignee: Ellem Bioteknik AB
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Filing: 1990-07-18
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Granted: —
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Expires: 2010-07-18
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Abstract

Abstract A method of preparing an implant body in order to optimize the healing time of said implant, comprising bringing the implant body for a limited period of time into contact with a hydrogen peroxide solution at least on the surfaces intended to come into contact with surrounding tissue when implanted, the treated surfaces being cleaned by rinsing. The treatment of the implant surface with hydrogen peroxide can be supplemented with incorporation of biomolecules, such as peptides, proteins and steroids, and also other substances such as inorganic ions and crystals. The compounds to be coupled to the implant surface may promote the healing and/or binding of the surrounding tissue.

Inventors

  • 👤 Lars-Magnus Bjurstén
  • 👤 Pentti Tengvall
  • 👤 Ingemar LUNDSTRÖM

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 11:13
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/54; A61L27/02; A61L27/04; A61L27/06; A61L27/28; A61L27/30; A61L27/306; A61F; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61L2300/00; A61L2300/20; A61L2300/22; A61L2300/222; A61L2300/25; A61L2300/252

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 53 words
A method of preparing an implant body for implantation in order to optimize the healing time of said implant, comprising bringing the implant body into contact with a hydrogen peroxide solution at least at the surfaces intended to come into contact with surrounding tissue when implanted, and then cleaning said surfaces by rinsing.
Claim 2
Independent Claim 53 words
A method of preparing an implant body for implantation in order to optimize the healing time of said implant, comprising bringing the implant body into contact with a hydrogen peroxide solution at least at the surfaces intended to come into contact with surrounding tissue when implanted, and then cleaning said surfaces by rinsing.
Claim 3
Dependent Claim 18 words
A method as claimed in claim 1, wherein said implant surfaces are immersed in a hydrogen peroxide solution.
Claim 4
Dependent Claim 20 words
A method as claimed in claim 1, wherein said implant surfaces are painted or sprayed with a hydrogen peroxide solution.
Claim 5
Dependent Claim 27 words
A method as claimed in claim 1, wherein, after rinsing, the implant body is stored in an inert environment until it is to be used for implantation.
Claim 6
Dependent Claim 18 words
A method as claimed in claim 4, wherein water or a salt solution is used as rinsing liquid.
Claim 7
Dependent Claim 19 words
A method as claimed in claim 1, wherein the implant body consists of titanium or is coated with titanium.
Claim 8
Dependent Claim 19 words
A method as claimed in claim 1, wherein a 1-30% solution of hydrogen peroxide is used as treating liquid.
Claim 9
Dependent Claim 25 words
A method as claimed in claim 1, wherein the duration of contact for the implant body with the treating liquid is at least 1 minute.
Claim 10
Dependent Claim 15 words
A method as claimed in claim 8, wherein said duration of contact is 1-30 minutes.
Claim 11
Dependent Claim 23 words
A method as claimed in claim 1, wherein biomolecules are incorporated into the surface layer of said implant during the hydrogen peroxide treatment.
Claim 12
Dependent Claim 21 words
A method as claimed in claim 10, wherein said biomolecules are selected from the group consisting of peptides, proteins and steroids.
Claim 13
Dependent Claim 27 words
A method as claimed in claim 1, wherein biomolecules are added to the treated implant surface after the hydrogen peroxide treatment but before rinsing said implant surfaces.
Claim 14
Dependent Claim 21 words
A method as claimed in claim 12, wherein such biomolecules are selected from the group consisting of peptides, proteins and steroids.
Claim 15
Dependent Claim 28 words
A method as claimed in claim 1, wherein inorganic ions and/or crystals are introduced into said implant surface layer by adding these substances to the hydrogen peroxide solution.
Claim 16
Dependent Claim 20 words
A method as claimed in claim 12, wherein said added ions and crystals include Ca²⁺, Mg²⁺, Zn²⁺, PO⁴⁻ and hydroxylapatite.

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