EP0379156A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Improved hydrophilic lubricious coatings
Assignee: Union Carbide Chemicals and Plastics Technology LLC
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Filing: 1990-01-16
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Granted: —
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Expires: 2010-01-16
Abstract
Abstract A new method is provided to impart a hydrophilic lubricious coating onto articles such as medical devices. A device, for example a catheter, is first contacted with a polyisocyanate solution, to provide coupling, then contacted with a poly(carboxylic acid) solution to give a coating, and is then finally oven dried. These coatings have lubricity that only becomes manifest upon exposure to water or body fluids, and moreover, are also long lasting and have good abrasion resistance. This combination of properties is not available from other currently used or proposed coatings such as Teflon.
Inventors
- 👤 You-Ling Fan
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-22 23:25
CPC Classifications
B; B05; B05D; B05D5/00; B05D5/04; A; A61; A61L; A61L29/00; A61L29/08; A61L29/085; B05D3/00; B05D3/10; B05D3/101; C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/62; C08G18/6216; C08G18/625; C08G18/70; C08G18/703; C08G18/705; C08J; C08J7/00; C08J7/04; C08J7/042; C08J7/0427; C08J7/043; C08J7/046; C08J7/056; C08J7/06; C08J7/065; B05D2201/00; B05D5/08; C08J2375/00; C08J2375/04; C08J2375/12; C08J2433/00; C08J2433/04; C08J2433/06; C08J2433/08
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
97 words
A method of covering at least a portion of a substrate with a hydrophilic coating having good abrasion resistance and which exhibits an increased lubricity when contacted with an aqueous-containing fluid, said method comprising the steps of: (1) contacting said substrate with a polyisocyanate contained in at least one first inert solvent to provide at least a partially coated substrate; (2) contacting said coated substrate with a carboxylic acid-containing polymer contained in at least one second solvent to provide a multiple coated substrate; and (3) thereafter drying said multiple coated substrate to provide a hydrophilic, lubricious coating.
Claim 2
Independent Claim
97 words
A method of covering at least a portion of a substrate with a hydrophilic coating having good abrasion resistance and which exhibits an increased lubricity when contacted with an aqueous-containing fluid, said method comprising the steps of: (1) contacting said substrate with a polyisocyanate contained in at least one first inert solvent to provide at least a partially coated substrate; (2) contacting said coated substrate with a carboxylic acid-containing polymer contained in at least one second solvent to provide a multiple coated substrate; and (3) thereafter drying said multiple coated substrate to provide a hydrophilic, lubricious coating.
Claim 3
Dependent Claim
15 words
The method of claim 1 wherein said substrate is a medical device, e.g. a catheter.
Claim 4
Independent Claim
20 words
The method of at least one of the claims 1 to 2 wherein said mixture contains at least one surfactant.
Claim 5
Independent Claim
18 words
The method of at least one of the claims 1 to 3 wherein said polyisocyanate is a diisocyanate.
Claim 6
Independent Claim
21 words
The method of at least one of the claims 1 to 4 wherein said coated substrate is thermoformed to different shapes.
Claim 7
Independent Claim
28 words
The method of at least one of the claims 1 to 5 wherein said carboxylic acid-containing polymer has a molecular weight of from about 200,000 to about 5,000,000.
Claim 8
Independent Claim
25 words
The method of at least one of the claims 1 to 6 wherein said carboxylic acid-containing polymer is a poly(acrylic acid) or a poly(methacrylic acid).
Claim 9
Independent Claim
20 words
The method of at least one of the claims 1 to 7 wherein said isocyanate is applied as a dispersion.
Claim 10
Independent Claim
21 words
The method of at least one of the claims 1 to 7 wherein said poly(isocyanate) is applied as an oil-in-water emulsion.
Claim 11
Independent Claim
23 words
The method of at least one of the claims 1 to 9 wherein said carboxylic acid containing polymer is applied as an emulsion.
Claim 12
Independent Claim
116 words
A method of at least one of the claims 1 to 10 wherein the coated substrate is contacted with a poly(acrylic acid) polymer of the formula: where n = 0-0.95 mole fraction of neutralized acid moieties; m = 0.05-1.0 mole fraction of acid moieties with the proviso that n+m = 1; X₁, X₂, X₃ are each a hydrogen atom or a monovalent organic radical; Y is a single bond or a divalent organic radical; Z is a metallic ion or a tertiary ammonium ion; and p is a number such that the polymer has a molecular weight between about 200,000 and about 5,000,000; said carboxylic acid-containing polymer contained in at least one second inert organic solvent.
Claim 13
Independent Claim
23 words
The method of at least one of the claims 1 to 11 wherein at least one additive is incorporated into said coated substrate.
Claim 14
Dependent Claim
14 words
The method of claim 12 wherein said additive is an antithrombogenic agent, e.g. heparin.
References Cited (Backward Citations)
No citation records indexed.
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